Anti-cholinergic drugs are good for the brain, even if they seem to impair short term memory. Choline, cocaine, and estrogen "improve" memory through the same mechanism - i.e. excitotoxicity. Anything that excites the brain cells will probably improve memory in the short run but in the long run will kill brain cells and cause some type of neurodegenerative condition. Just look at all the trials for Alzheimers using cholinergic drugs - i.e. they all failed.
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Choline does not cause Excitoxicity @haidut
CDP-choline prevents glutamate-mediated cell death in cerebellar granule neurons. - PubMed - NCBI