alcoholism

  1. haidut

    Alcohol Brain Damage Due To Iron Accumulation; Vitamin B1 To The Rescue

    Chronic alcohol abuse is highly detrimental to health and especially to the brain. Alcohol puts the body in a reductive state and depletes vitamin B1 (thiamine) stores. If the B1 deficiency becomes severe enough it manifests through what is clinically known as Wernicke-Korsakoff syndrome (WKS)...
  2. haidut

    Pregnenolone Is A Potent (functional) Endotoxin (TLR4) Antagonist

    It seems that pregnenolone is finally starting to look exciting to the medical industry. In addition for its intensive studies for a variety of mental issues, now studies are coming out demonstrating its endotoxin (LPS) antagonism effects. As most forum users know, endotoxin exerts its effects...
  3. haidut

    Niacinamide Can Treat Alcoholic Liver Disease

    As many forum users have probably heard on the news, alcohol abuse is now a leading cause of death in young people under 35. It is projected to soon surpass drug overdose as a cause of death in this demographic. Millennials are dying of alcohol-related liver disease at increasing rates The...
  4. haidut

    Alcohol "addiction" Driven By Endotoxin (TLR4)

    I posted a few threads in the past about addiction, and especially alcohol addiction being driven by high cortisol and low dopamine. This new study adds more pieces to the puzzle by implicating endotoxin in that process as well. Just as importantly, the study found that the desire to drink...
  5. haidut

    Stress Leads To Lower Dopamine And More Drinking

    The study was really on alcohol consumption what affects it. It has been known since the 1960s that people drink more when under stress but to this day mainstream medicine denies that there is a causative link between stress and substance abuse. I posted a few studies showing that "addicts" have...
  6. haidut

    Low-dose Glycine May Treat Alcoholic Delirium / Hallucinosis In Humans

    The symptoms of alcohol withdrawal and its associated delirium are due mostly to serotonin overload and functional GABA deficiency. As such, anti-serotonin drugs can be very beneficial but they often have side effects and cannot be freely obtained. This human study showed that a single...
  7. haidut

    Dopaminergic Drugs Like Bromocriptine May Treat Alcoholilsm

    This study is interesting for several reasons. On one hand, it combines well with previous studies on addiction I posted about - i.e. that "addiction" is a physiological state in which a person attempts to mitigate the effects of "inescapable stress" as animal studies commonly call the issue...
  8. haidut

    Cyproheptadine - A Wonder Drug?

    Hi all, As you many of you know, Ray Peat has mentioned cyproheptadine as a possible option for correcting certain physiological processes that have been derailed after years of eating PUFA, being exposed to chronic stress, toxins, endotoxin, battling chronic diseases, etc. As I mentioned in...
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