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endotoxin

  1. haidut

    Cancer cells deprive immune cells of energy by devouring their mitochondria

    In a description that could be a good plot for a horror-movie, the study below demonstrates that the immune failure often seen in cancer is, again, bioenergetic in origin. More specifically, the immune system cells are getting literally the energy (i.e. mitochondria) sucked out of them by cancer...
  2. Kvothe

    Anti-Peat Compared to soybean oil and olive oil coconut oil results in endotoxemia and fatty liver

    Consumption of soybean or olive oil at recommended concentrations increased the intestinal microbiota diversity and insulin sensitivity and prevented fatty liver compared to the effects of coconut oil Author links open overlay panelValeriaLópez-Salazarab1 Mónica...
  3. aliml

    The homeoviscous adaptation to dietary lipids (HADL) model explains controversies over saturated fat, cholesterol, and cardiovascular disease risk

    SFAs play the leading role in 1 of the greatest controversies in nutrition science. Relative to PUFAs, SFAs generally increase circulating concentrations of LDL cholesterol, a risk factor for atherosclerotic cardiovascular disease (ASCVD). However, the purpose of regulatory mechanisms that...
  4. haidut

    Endotoxin (LPS) may directly cause cancerization of normal cells

    A very interesting new study, which confirms the direct causal role LPS has in chronic inflammatory diseases, and especially in cancer. In addition, the study may answer one of the long-standing critiques the medical establishment has always had against the hypothesis that LPS causes cancer (and...
  5. Mauritio

    1 dose of endotoxin causes endothelial dysfunction for up to 1 week

    In this study they injected endotoxin into the hand of healthy volunteers. As it turned out, one dose of endotoxin lead to persistent constriction of the blood vessel that took up to 1 week to recover! There's molecules like nitric oxide, serotonin , bradikinin ,arachidonic acid or CO2 that...
  6. haidut

    PUFA required for periodontal disease, aspirin may help

    It is common knowledge even among mainstream dentists that periodontal disease is caused by bacteria accumulating under the gums, which over time leads to chronic inflammation and thus destruction of both gum tissue and the alveolar/jaw bone underneath the gums. Another "new" discover is that...
  7. haidut

    Endotoxin (LPS) causes rheumatoid arthritis...and COVID-19

    A great new study, which is perhaps the first to directly point the finger at endotoxin as perhaps the main cause of rheumatoid arthritis (RA). RA is an "autoimmune" condition and not only shares symptoms with other similar conditions such as Lupus, psoriasis, MS, etc, but now all of them are...
  8. RenaissanceMan

    Oral spore-based probiotic supplementation was associated with 42% reduction of post-meal dietary endotoxin

    https://pubmed.ncbi.nlm.nih.gov/28868181/ AIM To determine if 30-d of oral spore-based probiotic supplementation could reduce dietary endotoxemia. METHODS Apparently healthy men and women (n = 75) were screened for post-prandial dietary endotoxemia. Subjects whose serum endotoxin concentration...
  9. 'peataphysique

    Childhood dementia claiming young lives | A Current Affair

  10. RenaissanceMan

    Theanine Ameliorates Neuroinflammation And Protects Against Endotoxin-Induced Inflammation and Acute Liver Injury

    https://pubmed.ncbi.nlm.nih.gov/29969892/ Theanine, a unique bioactive constituent from tea ( Camellia sinensis) leaves, is widely used as a functional ingredient and dietary supplement. To evaluate the anti-inflammatory and hepatoprotective effects of theanine and its molecular mechanism, the...
  11. RenaissanceMan

    Vitamin K alleviates the reduction in testosterone production induced by Endotoxin (lipopolysaccharide) administration in rat testis

    https://pubmed.ncbi.nlm.nih.gov/21894328/ PMID: 21894328 DOI: 10.1039/c1fo10058k Abstract Vitamin K is essential for the posttranslational modifications of blood coagulation factors and proteins present in the bone matrix. Vitamin K is distributed not only in the liver and bones but is also...
  12. Soren

    Pregnenolone vs Progesterone for Back Pain, Endotoxin, Parkinsons Disease

    As some on this forum might know my mother suffers from Parkinson's disease which I have been attempting to treat with a number of serotonin blocking substances. Circumstances of the Pandemic and her own disposition have made it very difficult to get her into consistently good habits and...
  13. haidut

    Endotoxin (LPS) as a cause of liver disease, obesity and diabetes

    The first article below is actually about praising fermented foods, which I don't really agree with. So, I am posting it mostly because of the quote on endotoxin/LPS, which is a very rare finding in published medical literature since medicine does not recognize chronic, low-grade endotoxemia as...
  14. haidut

    Blocking the endotoxin receptor (TLR4) may prevent / treat hearing loss

    I did a post a few months ago on the connection between tinnitus and serotonin - i.e. using anti-serotonin drugs may treat tinnitus. Since tinnitus is almost always a precursor state to hearing loss (and eventually deafness), the two conditions obviously go hand-in-hand and are likely caused by...
  15. haidut

    Endotoxin (LPS) may be the cause of fatal lung damage in COVID-19

    Yet another study, which demonstrates that there is virtually no disease (acute of chronic, infections or not) where the infamous LPS does not play a causative role. As it turns out, the often fatal inflammatory reaction (cytokine storm) that usually kills patients with COVID-19 in ICU, is...
  16. haidut

    Silica, present in most supplements/food, activates the endotoxin receptor (TLR4)

    Many of my readers know about the health risks of silica - a substance doctors and pundits call completely "benign, present in virtually all commercially sold dietary supplements and also in most commercially sold food (even organic ones!). The most commonly used form commercially is silicon...
  17. Hans

    How to protect yourself against exercise-induced endotoxin absorption

    Endotoxin can significantly negatively affect your health, from chronic low-grade inflammation, joint degeneration, organ inflammation and dysfunction, brain degeneration, insulin resistance, etc. Most people know that gut dysbiosis can increase endotoxin production and absorption into the body...
  18. P

    Cool coffee video

    View: https://youtu.be/rNbWDnUMaEk This video talks a lot about the key reasons Peat and others in the bioenergetic community think coffee is so valuable. Well done.
  19. shine

    L. plantarum protects testicles & lowers inflammation/endotoxin

    It is well known that phtalates used in plastics are endocrine disruptors and damage testicular tissue. This study is showing that Lactobacillus plantarum (LP) alleviates testicular damage, increases testosterone back to normal levels, lowers inflammatory mediators like TNF-a, IL-1b and IL-6 and...
  20. Ismail

    Endotoxin (LPS) drives CD38 expression and therefore seems to effect NAD levels

    How To Inhibit CD38 As We Age | LPS Drives CD38 Expression | Prof Covarrubias Interview Series Ep5
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