Mauritio
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- Joined
- Feb 26, 2018
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In this study they looke at some blood markers in patients with RA.
As it turns out they have slighlty higher cortisol and way higher serotonin: their serotonin level was 3 times higher!
Their melatonin level was a lot lower than that of the control group, which indicates less downstream conversion of serotonin--> melatonin.
This gives even more evidenve to the idea that RA starts in the gut and is strongly connected with serotonin and endotoxin.
"Patients with RA had higher plasma cortisol (324.6 ng/ml vs. 292.9 ng/ml) and serotonin concentrations (67.9 ng/ml vs. 22.1 ng/ml) and lower plasma melatonin (116.8 pg/ml vs. 330.2 pg/ml) compared to controls."
- Association between levels of serotonin, melatonin, cortisol and the clinical condition of patients with rheumatoid arthritis - PubMed
As it turns out they have slighlty higher cortisol and way higher serotonin: their serotonin level was 3 times higher!
Their melatonin level was a lot lower than that of the control group, which indicates less downstream conversion of serotonin--> melatonin.
This gives even more evidenve to the idea that RA starts in the gut and is strongly connected with serotonin and endotoxin.
"Patients with RA had higher plasma cortisol (324.6 ng/ml vs. 292.9 ng/ml) and serotonin concentrations (67.9 ng/ml vs. 22.1 ng/ml) and lower plasma melatonin (116.8 pg/ml vs. 330.2 pg/ml) compared to controls."
- Association between levels of serotonin, melatonin, cortisol and the clinical condition of patients with rheumatoid arthritis - PubMed