1. youngsinatra

    Human study — Betaine (TMG) nearly doubles total testosterone & lowers cortisol by 30%

    Would like to hear your thoughts on this one: The total testosterone in the betaine group is around 1500ng/dL. :o
  2. haidut

    PARADOX: Cortisol promotes inflammation, drives Alzheimer's Disease (AD)

    It looks like serotonin (5-HT), commonly known as the "happy hormone" has a serious competitor for the title of the most grossly mischaracterized substance in medicine. That serious competitor is cortisol, in both its synthetic and bioidentical forms, commonly known as the "master of...
  3. haidut

    Most cancers overproduce cortisol, and it accelerates their growth

    This post is right on the heels of the one I just did on cortisol stimulating its own production and driving cardiovascular disease, obesity, diabetes, etc. The study below demonstrates that most tumor types known to medicine overexpress the rate-limiting enzyme for cortisol synthesis known as...
  4. haidut

    Cortisol stimulates its own synthesis (peripherally), drives obesity/diabetes/CVD

    Synthetic/bioidentical glucocorticoids (GC) are perhaps the most widely used steroids clinically. In addition, the HPA axis, culminating in cortisol production, is one of the most widely studied mechanisms in regards to many chronic diseases including obesity, diabetes, CVD, mental conditions...
  5. J

    Relora estrogenic??

    I have had success using Relora in the past to lower cortisol. I decided to give it another try and have been taking for several nights before bed. Yesterday morning I woke up from my sleep with a thumping heart and sweating hot flash. I'm so tired of certain supplements giving me this effect...
  6. J

    Severely dry skin from Vitex/Calcium D glucarate

    Ok in a desperate attempt to lower my prolactin and estrogen, I ended up with dry skin and hair. I notice with Vitex it caused either dopamine or adrenaline surges at high dose. Along with the Calcium D glucarate I noticed my hair was starting to sound like straw when I tried to tie it up. My...
  7. haidut

    Another "paradox" - elevated cortisol, from high-fat diet, increases inflammation

    Over the last year or so I posted about several studies demonstrating that even short-term usage of glucocorticoids may be a double-edged sword. Namely, while it is beyond doubt that, acutely, glucocorticoids suppress inflammation, those studies demonstrated that the glucocorticoids upregulated...
  8. haidut

    Androgens, glucocorticoids are antagonistic - former inhibit, latter promote fat gain

    As most of my readers know, androgenic steroids are considered extremely dangerous by medicine and are in fact outlawed in most "developed" countries. Aside from the (in)famous "roid rage", medicine claims that a large number of chronic conditions (spanning the spectrum from cosmetic to...
  9. youngsinatra

    Anti-Peat Cortisone Therapy Puts Hypothyroidism Into Remission In Adrenal Insufficiency? „It is well known that untreated or suboptimal treatment of AAD leads to an increase in thyrotropin (TSH) levels, which can potentially lead to overdiagnosis of hypothyroidism...
  10. TruffleGnocchi

    DHEA levels in young children? And how to prevent it's conversion?

    There are papers talking about DHEA decline and supplementation could resolve a lot of problems related to aging. I see some sources say DHEA levels are low or significantly lower in childhood than in teens or young adults. Is this really the hormone of such importance if this is true? When I...
  11. haidut

    Hormonal birth control puts women in chronic stress, by blocking progesterone synthesis

    A truly remarkable study as it exposes so many lies that Big Pharma and its medical accomplices would rather not become public knowledge. Since most hormonal birth control (pills, patches, IUD, injections, etc) contain a combination of an estrogen and a synthetic progestin, it implicates both...
  12. M

    Best Ways To Start Thyroid

    Hey All, I know there has been good & bad experiences while taking thyroid hormone. Myself being one of them.. I was always good but once i stopped I seemed to never tolerate it again. I believe I wasn’t able to tolerate NDT because of how much stress i was under during that time. (Ths...
  13. haidut

    Chronic stress doubles the weight gain from high-fat diets

    I am only posting this to demonstrate that the (in)famous claim so many doctors and dietitians and public health figures like to quote (calories in = calories out) does not hold and in fact body weight is heavily influenced by environmental conditions as well, such as chronic stress. As the...
  14. cs3000

    SIPPING sugar / sweetened water every 5 minutes for stress relief

    Sugars acute anti-stress property isnt just sugar itself, it's the sweetness signalling that creates rapid adjustment to CRH stress neurons (at first i thought that was due to the dopamine release , but that doesn't look likely actually) Corticotropin Releasing Hormone releases ACTH which...
  15. Mauritio

    Rheumatoid Arthritis patients have higher serotonin and cortisol levels

    In this study they looke at some blood markers in patients with RA. As it turns out they have slighlty higher cortisol and way higher serotonin: their serotonin level was 3 times higher! Their melatonin level was a lot lower than that of the control group, which indicates less downstream...
  16. Mauritio

    Pregnenolone reduces alcohol cravings in humans

    This study showed that giving people 300 or 500mg of Pregnenolone reduced cravings in alcoholics and also normalized their stress parameters like cortisol and ACTH. I cant get the full text, but the abstract only mentions the 300mg dose as effective, so I'm not sure about the 500mg dose. But...
  17. M

    Can thyroid be used short term to balance hormones?

    is it possible to use thyroid for a couple of months to rebalance your body back..TSH.. cortisol.. Dhea..test.. etc. and drop it once it did what it was supposed to do? Thyroid rddit pages are brutal and say “NO YOU MUST BE ON FOREVER YOU WILL F YOURSELF” So im lost here lol
  18. haidut

    STUDY: Glycine may treat depression; MEDIA: Glycine may cause depression

    The level of misreporting in mainstream media is reaching criminal levels. For example, there have been many studies discovering that an increase in the activity of the serotonin transporter (SERT), which results in lower levels of extracellular serotonin, results in alleviation of depression or...
  19. haidut

    Hair glucocorticoid levels predict future cardiovascular disease (CVD)

    Ever since we launched our hair/nail steroid analysis service couple of years ago, I have been seeing a steadily increasing number of studies on using hair/nail steroid analysis to predict future risk and also assess severity of (already existing) many chronic conditions. While most of the...
  20. M

    Urgent Help To balance Cortisol Levels Repair Adrenals

    Can anyone recommend the best steps to help balance out cortisol & aid my adrenals? I wake up fine & feel great all morning which allows me to work hard, commit to my tasks, my patience is better, motivation, etc until about an hour or two after lunch & the rest of the day feels very low...