cortisol

I've noticed since focusing on maximizing a high dopamine, low serotonin, low cortisol state that I've become much more passive regarding topics that I was much more fired up about a few years ago. I've spoken of having much more (far) right leaning views during the most stressful periods of my...

What are your guys's thoughts about this? I can't use metergoline as an anti-serotonin supp because when I stop I get horrific symptroms of DAWS. Cypro is okay, but I don't like the dopamine receptor antagonizing effects and I am also finding it very hard to stop. Any time I stop the cypro, I...

What was your experience with CT3M?

2 Years ago Symptoms : All day Anxiety, Depression Emergency state. Any bad thought would cause belly contraction and a cycle of stress diffucult to calm. Sleepness, GERD intense headaches when doing mental effort. I am understanding now that all of these could be symptoms of very low metabolism...

As above

Hey, I am a final year medical student. For years I had incredibly fatigue and other low-cortisol issues. After doing a LOT of research, I collected a list of methods we can try to raise our cortisol naturally and therefore to help get rid of HPA-dysfunction. I share this here because I am sure...

Hi all, Wanted to share post i found that might be interesting for peoples who do not tolerate thyroid due to low cortisol, as below: """Hello, everyone. Thought I'd drop back in with a final update as I've managed to fix all of my problems. It turned that whilst my cortisol was high-normal...

I’m a young female and I have sex once or twice a week, but I stopped masturbation and sometimes even withhold my orgasms. I am aware that the negative hormonal effects of masturbation is worse in men, but I am curious the effect it has on women. I have noticed that my body hair grows slower...

A very interesting study that highlights yet again the connection between chronic stress and ill systemic health, especially cardiovascular disease (CVD). The study demonstrates that people who had experienced a heart attack have dramatically higher higher cortisol and adrenaline/noradrenaline...

A really interesting study, which will likely generate more than a few hateful emails for my Inbox :): Anyways, as the study demonstrates, fasting achieves these negative effects due to the elevated fatty acids working through PPAR activator PGC-1α, to activate both the estrogen receptor (ER)...

Many of my readers already know about the unreliability of using steroid blood tests as diagnostic methods, except in cases where the values are so extreme that are unlikely to be temporary fluctuations. Saliva tests for steroids are even less reliable, even though combining both saliva and...

A great study for a number of reasons. First, it discussed openly that in animal research circles cortisol administration is considered an official and reliable method of causing major depression. As the article states, for some reason human medical circles have been unwilling to accept the...

In a recent post of mine I discussed the effects of cortisol on various aminotransferases (especially TAT), their role as biomarkers of catabolism, and how inhibitors of said aminotransferases have a potent anti-catabolic / anabolic effects. In that same post, I also described how cortisol (a...

During the early days of anabolic-androgenic steroid (AAS) science, it quickly became apparent that the ability of AAS to preserve and/or increase muscle mass was related to their ability to reduce/block the expression of amino acid catabolic enzymes such as tyrosine aminotransferase (TAT). TAT...

Did anyone successfully increase cortisol to actually successfully supplement the thyroid? I was on adrenal cortex but i seem to build a tolerance. I will be trying tomorrow pregnenolone but im sure i cant tolerate much as i don't sleep 3 days after 100mg. Few weeks back i was taking around...

Hello, I am a medical student in my last year. For a few years I have been replacing all of my major hormones (see here) and I have been both high and low in many different constellations. From all this I learned 2 things. Each hormone deficiency can cause chronic fatigue. Each hormone...

I'm looking for advice to help both my sister and mother with their longstanding health issues. My mother is in her mid-50s and has been suffering from severe Rheumatoid Arthritis for as long as I can remember. She told me she has been on Prednisone for the majority of my life (I'm 31). She was...

I want to share my journey with hormone replacement because I believe it might be useful to others. Beacuse hormones are extensively talked about here on RPF, I do think that others might benefit from some of the stuff I learned along my way. I am a medical student in my last year. I replace...

The metabolic causes of cancer are slowly starting to be recognized, and especially the role of cortisol. I recently did a post on the role of cortisol in triple-negative breast cancer and the protective effects of androgens such as DHT. Now, mainstream medicine does not deny that androgens have...

Fueling your workouts properly is key to performing optimally. Sometimes is difficult to get it right. Either the amount is not enough, or we get gastric upset, or worse, hypoglycemia during the workout. With the right carb source, we can prevent that from happening. A few benefits of...