Jiaogulan Protects and Strengthens the Nervous System
Jiaogulan protects and enhances the function of the central and peripheral nervous systems, mainly through its antioxidant properties and its ability to regulate Nitric Oxide production.
Nitric Oxide plays an important role in learning and memory by helping nerve cells in the brain to communicate with each other.197, 198 It is involved in neurotransmitter release, neural development and regeneration, synaptic plasticity and regulation of gene expression.199
At normal concentrations, Nitric Oxide protects the nerve cells from damage and cell death. However, at high concentrations it becomes toxic to the nerve cells and can cause cell injury and cell death.200
Overproduction of Nitric Oxide in the nervous system has been linked to Alzheimer’s disease, Parkinson’s disease, multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), Huntington’s disease, and depression.201
In addition, free radical damage has been shown to play a major role in the development of neurodegenerative diseases such as Alzheimer’s and Parkinson’s.202, 203
In light of this, it’s not surprising that Jiaogulan has been shown to help prevent both Alzheimer’s 204, 205, 206, 207 and Parkinson’s 37, 208, 209, 210, 211, 212, which are the 6th and 14th leading causes of death in the United States respectively. It may also be effective against optic neuritis, although further studies are needed.213
In both human and animal studies, Gynostemma was shown to improve brain functions like memory, concentration, and learning, especially with the elderly.156, 214, 215, 216
The herb also helps protect against and recover from brain and memory damage induced by alcohol217, 218 and free radicals31, 34, 35, 36, 37, 38, 49, as well as damage and cognitive impairment from ischemia-reperfusion and hypoxia due to stroke and other causes.34, 218, 219, 220, 221, 222, 223, 224, 225, 226, 227
A study with elderly cerebral infarction patients (a type of ischemic stroke) showed that administering Jiaogulan for a 12-week period improved their cognitive functions to a level close to that of normal elderly subjects who had not suffered a stroke. In addition, the improvements were better than that of a control group that was given Piracetam, a popular nootropic and brain-enhancing drug.228
A second clinical study using different evaluation methods showed identical results, and further improvement when treatment was continued for 12 more weeks (24 weeks in total).229
Jiaogulan can also prevent brain and nervous system damage caused by consumption of the popular flavor enhancing food additive Monosodium Glutamate (MSG).230, 231, 232, 233
Lastly, the herb was found to increase the excitability and stability of the brain during athletic competition. A Guiyang Medical College research group carried out testing on more than 300 professional athletes, including athletes of the China National Skating Team. All of the tested athletes reported that a Jiaogulan/Danshen recipe taken before the competition made them vigorous and alert, with quick reflexes and less nervousness. A control group taking Danshen alone did not feel increased stability and excitability of the nervous system during competition, although they also felt increased energy and endurance.234, 235
These effects have been demonstrated in several types of cancer, including:
Many top athletes and bodybuilders use Jiaogulan because it enhances their performance by energising the body and increasing physical strength, stamina, endurance and muscle tone.
This is also why Jiaogulan is given to race-horses.
If you’re involved in sports or workout at the gym, you will find that you can go through your usual training routine with less effort, or that you can endure a harder workout by only expending the same amount of effort as you did before.
Jiaogulan is able to increase athletic performance in several ways:
Nitric Oxide also stimulates growth hormone production236, which encourages fat reduction and muscle building.
Jiaogulan also improves the efficiency of the pumping action of the heart, so that it doesn’t work as hard to produce the same amount of blood flow. Again, more oxygen and nutrients reach the muscles and performance is improved.
A clinical study at the Guiyang Medical College with 30 normal healthy persons and 220 athletes showed that within 30 minutes after oral administration of a single dose of Jiaogulan combined with other Chinese medicinal herbs, all subjects responded with increased cardiac output and stroke volume, while heart rate and blood pressure did not change.237
Animal studies have confirmed this positive effect on heart function and have concluded that Jiaogulan’s effect is more potent than that of ginseng 103, 238
A number of studies involving forced swimming tests with animals have proven that Jiaogulan has a significant anti-fatigue effect and increases the endurance capacity in animals, enabling them to swim significantly longer before they get exhausted. In addition, these effects become stronger as the dose is increased.239, 240, 241, 242, 243, 244, 245, 246
Jiaogulan significantly increases glucose levels in the blood, liver and muscles, which is the fuel the muscles use and is therefore very important for the prolongation of endurance exercise.
Furthermore, Gynostemma decreases the amount of lactic acid (the build-up of which causes sore muscles the day after rigorous exercise) in the blood significantly and this is an important indicator for judging the degree of fatigue and means that Jiaogulan is able to postpone the appearance of fatigue and accelerate the recovery from fatigue.239, 240, 241, 242, 243, 244
Jiaogulan Slows Down Aging and Increases Longevity
Longevity isn’t just about reaching a ripe old age – it’s also about feeling and looking good as you get there!
While most people today choose anti-aging creams, surgery, and Botox, we believe in a more holistic approach to health and aging because youth, like beauty, is more than skin deep.
Jiaogulan was first discovered in China because of the unusually long life spans and good health of so many of its users in the mountainous regions where it grows.
When you drink Jiaogulan tea daily you will not only look younger, you will be younger and healthier.
The herb slows down aging from the inside out. It has a rejuvenating and healing effect on all organs and major systems due to its unrivaled ability to neutralize the free-radicals that damage and age your body by boosting production of the two most important endogenous antioxidants – superoxide dismutase (SOD) and glutathione.
These two antioxidants are crucial in preventing aging and promoting longevity. Please see the section on the Antioxidant properties of Jiaogulan for details and more scientific evidence.
In human clinical studies, administration of Jiaogulan three times daily for two months was beneficial for all 106 patients (in the study) in reducing general signs and symptoms of aging, such as fatigue, lack of energy, aversion to cold, diarrhoea, poor memory, decreased balance, insomnia, and excessive dreams.155
Studies with aging animals have shown that Jiaogulan improves their memory and learning ability 156, and rejuvenates their skin47, 48, 157. It was also found that the herb increases the thickness of the skin, boosts synthesis of collagen, and protects elasticity158. For extra skin benefit, you can also apply Jiaogulan tea topically, for example as a face rinse.
In addition, there have now been several studies that support claims the herb increases longevity.
In one study, a group of old mice were divided into two groups. After four months, all mice in the control group died, while only 50% of the mice in the Jiaogulan group died.159
In another study, the lifespan of fruit flies was increased by as much as 50% when given Jiaogulan.160 Other animal studies have also demonstrated increase in lifespan.161, 162
References
Jiaogulan protects and enhances the function of the central and peripheral nervous systems, mainly through its antioxidant properties and its ability to regulate Nitric Oxide production.
Nitric Oxide plays an important role in learning and memory by helping nerve cells in the brain to communicate with each other.197, 198 It is involved in neurotransmitter release, neural development and regeneration, synaptic plasticity and regulation of gene expression.199
At normal concentrations, Nitric Oxide protects the nerve cells from damage and cell death. However, at high concentrations it becomes toxic to the nerve cells and can cause cell injury and cell death.200
Overproduction of Nitric Oxide in the nervous system has been linked to Alzheimer’s disease, Parkinson’s disease, multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), Huntington’s disease, and depression.201
In addition, free radical damage has been shown to play a major role in the development of neurodegenerative diseases such as Alzheimer’s and Parkinson’s.202, 203
In light of this, it’s not surprising that Jiaogulan has been shown to help prevent both Alzheimer’s 204, 205, 206, 207 and Parkinson’s 37, 208, 209, 210, 211, 212, which are the 6th and 14th leading causes of death in the United States respectively. It may also be effective against optic neuritis, although further studies are needed.213
In both human and animal studies, Gynostemma was shown to improve brain functions like memory, concentration, and learning, especially with the elderly.156, 214, 215, 216
The herb also helps protect against and recover from brain and memory damage induced by alcohol217, 218 and free radicals31, 34, 35, 36, 37, 38, 49, as well as damage and cognitive impairment from ischemia-reperfusion and hypoxia due to stroke and other causes.34, 218, 219, 220, 221, 222, 223, 224, 225, 226, 227
A study with elderly cerebral infarction patients (a type of ischemic stroke) showed that administering Jiaogulan for a 12-week period improved their cognitive functions to a level close to that of normal elderly subjects who had not suffered a stroke. In addition, the improvements were better than that of a control group that was given Piracetam, a popular nootropic and brain-enhancing drug.228
A second clinical study using different evaluation methods showed identical results, and further improvement when treatment was continued for 12 more weeks (24 weeks in total).229
Jiaogulan can also prevent brain and nervous system damage caused by consumption of the popular flavor enhancing food additive Monosodium Glutamate (MSG).230, 231, 232, 233
Lastly, the herb was found to increase the excitability and stability of the brain during athletic competition. A Guiyang Medical College research group carried out testing on more than 300 professional athletes, including athletes of the China National Skating Team. All of the tested athletes reported that a Jiaogulan/Danshen recipe taken before the competition made them vigorous and alert, with quick reflexes and less nervousness. A control group taking Danshen alone did not feel increased stability and excitability of the nervous system during competition, although they also felt increased energy and endurance.234, 235
These effects have been demonstrated in several types of cancer, including:
- Liver (hepatoma)104, 105, 106, 107, 108, 109, 110, 111, 112, 113
- Lung114, 115, 116, 117, 118, 119, 120
- Prostate121
- Colorectal122, 123, 124, 125
- Esophageal 122, 126
- Oral127, 128, 129, 130, 131, 132, 133, 134, 135
- Brain136
- Stomach 137, 138
- Skin (melanoma)139, 140
- Uterus/cervix141, 142, 143
- Leukaemia 144, 145, 146, 147
- Sarcoma 147, 148
Many top athletes and bodybuilders use Jiaogulan because it enhances their performance by energising the body and increasing physical strength, stamina, endurance and muscle tone.
This is also why Jiaogulan is given to race-horses.
If you’re involved in sports or workout at the gym, you will find that you can go through your usual training routine with less effort, or that you can endure a harder workout by only expending the same amount of effort as you did before.
Jiaogulan is able to increase athletic performance in several ways:
- By regulating the production of Nitric Oxide.
- By improving heart function efficiency.
- By stimulating the production of the endogenous antioxidants glutathione and superoxide dismutase.
Nitric Oxide also stimulates growth hormone production236, which encourages fat reduction and muscle building.
Jiaogulan also improves the efficiency of the pumping action of the heart, so that it doesn’t work as hard to produce the same amount of blood flow. Again, more oxygen and nutrients reach the muscles and performance is improved.
A clinical study at the Guiyang Medical College with 30 normal healthy persons and 220 athletes showed that within 30 minutes after oral administration of a single dose of Jiaogulan combined with other Chinese medicinal herbs, all subjects responded with increased cardiac output and stroke volume, while heart rate and blood pressure did not change.237
Animal studies have confirmed this positive effect on heart function and have concluded that Jiaogulan’s effect is more potent than that of ginseng 103, 238
A number of studies involving forced swimming tests with animals have proven that Jiaogulan has a significant anti-fatigue effect and increases the endurance capacity in animals, enabling them to swim significantly longer before they get exhausted. In addition, these effects become stronger as the dose is increased.239, 240, 241, 242, 243, 244, 245, 246
Jiaogulan significantly increases glucose levels in the blood, liver and muscles, which is the fuel the muscles use and is therefore very important for the prolongation of endurance exercise.
Furthermore, Gynostemma decreases the amount of lactic acid (the build-up of which causes sore muscles the day after rigorous exercise) in the blood significantly and this is an important indicator for judging the degree of fatigue and means that Jiaogulan is able to postpone the appearance of fatigue and accelerate the recovery from fatigue.239, 240, 241, 242, 243, 244
Jiaogulan Slows Down Aging and Increases Longevity
Longevity isn’t just about reaching a ripe old age – it’s also about feeling and looking good as you get there!
While most people today choose anti-aging creams, surgery, and Botox, we believe in a more holistic approach to health and aging because youth, like beauty, is more than skin deep.
Jiaogulan was first discovered in China because of the unusually long life spans and good health of so many of its users in the mountainous regions where it grows.
When you drink Jiaogulan tea daily you will not only look younger, you will be younger and healthier.
The herb slows down aging from the inside out. It has a rejuvenating and healing effect on all organs and major systems due to its unrivaled ability to neutralize the free-radicals that damage and age your body by boosting production of the two most important endogenous antioxidants – superoxide dismutase (SOD) and glutathione.
These two antioxidants are crucial in preventing aging and promoting longevity. Please see the section on the Antioxidant properties of Jiaogulan for details and more scientific evidence.
In human clinical studies, administration of Jiaogulan three times daily for two months was beneficial for all 106 patients (in the study) in reducing general signs and symptoms of aging, such as fatigue, lack of energy, aversion to cold, diarrhoea, poor memory, decreased balance, insomnia, and excessive dreams.155
Studies with aging animals have shown that Jiaogulan improves their memory and learning ability 156, and rejuvenates their skin47, 48, 157. It was also found that the herb increases the thickness of the skin, boosts synthesis of collagen, and protects elasticity158. For extra skin benefit, you can also apply Jiaogulan tea topically, for example as a face rinse.
In addition, there have now been several studies that support claims the herb increases longevity.
In one study, a group of old mice were divided into two groups. After four months, all mice in the control group died, while only 50% of the mice in the Jiaogulan group died.159
In another study, the lifespan of fruit flies was increased by as much as 50% when given Jiaogulan.160 Other animal studies have also demonstrated increase in lifespan.161, 162
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