Hello guys!
So I suffer from severe scalp inflammation after stopping finasteride and losing hair fast. I think it is relates to my gut and have started to use charcoal and keeping the gut clean. Eating low FODMAP easily digestible carbs while being nutrient replete with chicken liver/heart. Also using the carrot salad. But I am not able to stop the dry scalp and itching.. only with long scalp massages and cortizone (betnovate) it goes away temporarily. (Tried ZIX and essential oils aswell). But it always comes back!
DHT arrives when there is inflammation so I am sure limiting DHT would be beneficial to my problems. I am not willing to risk systemic absorbtion, or atleast keep it to a minimum. There is a new trend of topical dutasteride and several people have posted blood tests before and after of serum DHT decreasing max 10% after application of this powerful 5ar inhibitor topically. Dose 0.02%-0.05% preferably in a liposomal vehicle seems to keep the DHT nuked only in the galea. Some people have already seen results in a discord group. (Cant link since I am a new member)
Search for More plates more dates on youtube: topical dutasteride)
Anyone with an opinion on this?
"The idea behind topical dutasteride has to do with the chemical properties compared to finasteride. At the molecular level, dutasteride is more difficult to deliver as a topical agent to be absorbed through the skin due to the size of dutasteride molecules. They are larger than those of finasteride. This difficulty however becomes an advantage as the difficulty to get past the subcutaneous layer may prevent systemic absorption. The molecular size prevents deep penetration. In addition, dutasteride has a high lipophilicity of 4.94, compared to 3.03 of finasteride, which means it is less water soluble than finasteride or more “greasy”. This higher lipophilicity can in theory help dutasteride to remain in the skin longer as these properties tend to preclude the paracellular and follicular routes of ingress into the skin."
So I suffer from severe scalp inflammation after stopping finasteride and losing hair fast. I think it is relates to my gut and have started to use charcoal and keeping the gut clean. Eating low FODMAP easily digestible carbs while being nutrient replete with chicken liver/heart. Also using the carrot salad. But I am not able to stop the dry scalp and itching.. only with long scalp massages and cortizone (betnovate) it goes away temporarily. (Tried ZIX and essential oils aswell). But it always comes back!
DHT arrives when there is inflammation so I am sure limiting DHT would be beneficial to my problems. I am not willing to risk systemic absorbtion, or atleast keep it to a minimum. There is a new trend of topical dutasteride and several people have posted blood tests before and after of serum DHT decreasing max 10% after application of this powerful 5ar inhibitor topically. Dose 0.02%-0.05% preferably in a liposomal vehicle seems to keep the DHT nuked only in the galea. Some people have already seen results in a discord group. (Cant link since I am a new member)
Search for More plates more dates on youtube: topical dutasteride)
Anyone with an opinion on this?
"The idea behind topical dutasteride has to do with the chemical properties compared to finasteride. At the molecular level, dutasteride is more difficult to deliver as a topical agent to be absorbed through the skin due to the size of dutasteride molecules. They are larger than those of finasteride. This difficulty however becomes an advantage as the difficulty to get past the subcutaneous layer may prevent systemic absorption. The molecular size prevents deep penetration. In addition, dutasteride has a high lipophilicity of 4.94, compared to 3.03 of finasteride, which means it is less water soluble than finasteride or more “greasy”. This higher lipophilicity can in theory help dutasteride to remain in the skin longer as these properties tend to preclude the paracellular and follicular routes of ingress into the skin."