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I don't believe this has been addressed in this thread. Does metergoline have the downstream effects on adrenaline as most dopamine agonists, such as caffeine, or is it absent from the ergoline class (specifically metergoline)?
Thanks for the reply, haidut. I will place an order for some next month; do you think it's safe to take long-term with cyproheptadine? I know they should synergize, but is there anything to be aware of (say blood thinning or similar?)
Thanks for the reply, haidut. I will place an order for some next month; do you think it's safe to take long-term with cyproheptadine? I know they should synergize, but is there anything to be aware of (say blood thinning or similar?)
I would use metergoline on its own. They are both non-specific serotonin antagonists and metergoline also has some antihistamine effects.
Can't comment on safety, so please ask a doctor before using.
Okay, so maybe platelets could be an issue with this + emodin + aspirin. I'd think there would be obvious physical signs before anything too detrimental, particularly with a very low dosage of metergoline. Thanks for the info.
@haidut would it be possible to make a transdermal 6-methycabergoline as described in the below pubmed article. The methycab would be both 5HT2a and 5HT2b antagonism.
@haidut would it be possible to make a transdermal 6-methycabergoline as described in the below pubmed article. The methycab would be both 5HT2a and 5HT2b antagonism.
Where would one go about disposing of Metergoline? I find it a bit sketch that so many people are obtaining who most likely aren't trained scientists using it in a laboratory.
Where would one go about disposing of Metergoline? I find it a bit sketch that so many people are obtaining who most likely aren't trained scientists using it in a laboratory.
Are you sure? That sounds a bit sketch as well, all the safety data sheets on Metergoline, as well as most lab chemicals advise highly not to put it down sink or toilets. Not really sure what to do with it so I guess i"ll just keep it for now.
Are you sure? That sounds a bit sketch as well, all the safety data sheets on Metergoline, as well as most lab chemicals advise highly not to put it down sink or toilets. Not really sure what to do with it so I guess i"ll just keep it for now.
Are you sure? That sounds a bit sketch as well, all the safety data sheets on Metergoline, as well as most lab chemicals advise highly not to put it down sink or toilets. Not really sure what to do with it so I guess i"ll just keep it for now.
That's just what the vendor has to say to cover themselves. If you notice, they have warning on ingestion or exposure to skin even though this chemical is meant to be ingested or applied to skin if used for experiments. The same MSDS is given for pretty much everything else, including things like aspirin and caffeine. Given how low the concentration is, if you dump it in the toilet or sink, by the time it reaches the water treatment plant it would be so diluted as to be undetectable. You don't think people dump their pills or creams or whatnot in the sewage system? What does your note from the pharmacy say on drugs you take, if any? Does it say not to dump in the toilet?
@haidut Just received my order of metergoline. I take cyproheptadine and I plan to start mirtazapine again. Is there a risk with serotonin syndrome with metergoline and mirtazapine or any other interactions? I would theoretically only try a very low-dose of metergoline, but there shouldn't be any worry of serotonergic effects for metergoline, correct?
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