So, are you saying that, if I buy kuinone with the olive oil option, the absorption is just .2 mg per drop on the skin?
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Kuinone - Liquid Vitamin K2 (MK-4)
- Thread starter haidut
- Start date
learnedhelpless
Member
Haidut said this
I can believe that the ethanol/sfa solvent would have 70% absorption rate, but I don't get how the mixed tocopherols, oleic acid solvent would have the same absorption? @haidut could you explain on how the oil has an equal absorption rate? Is it the vitamin E, or oleic acid acting as a strong penetration agent through the skin?
Brandin
Member
- Joined
- Dec 1, 2020
- Messages
- 486
When will this be restocked??
Because I have read that quinones interact with Vitamin E (apparently for the worse), should our rat should not take Kuinone/Lapodin with - any - product that has tocopherols in it, including Pansterone, 6 keto, Cortinon, and Allop?
Feel free to search the forum to confirm my answer. I have seen it posted multiple times that E and K compete for the same transport chemicals in our system. Therefore, you should separate their consumption by about 4 hours to minimize this competition.
I take kuinone in the morning. I take tocovit and other E-based supplements after lunch through bedtime.
Thanks.
I should have added:
Since oxidal contains methylene blue, and I think that is another electron transport chain chemical, like quinones, should oxidal also not be taken near anything with tocopherol?
OP
Yes, anything capable of withdrawing electrons should not be taken at the same time as vitamin E. So, methylene blue, CoQ10, emodin, tetracycline antibiotics, etc.
Haidut,
Thanks.
Would it make any difference if the oxidal (for example) and the product with Vit E (Pansterone, 6 Keto P4, etc) are taken topically?
I read somewhere that in topical use the protein binding may not even matter as both can enter the cell passively through diffusion.
OP
The passive diffusion is for local tissues, but eventually the compounds make it into the systemic circulation and may interact. It comes down to doses really. If you eat liver, you are also consuming vitamin K and E together since both are present in the liver. However, the amounts are such that the interaction would not generate sufficient amounts of the reactive chemicals that can cause issues. Those chemicals are basically (semi)oxidized derivatives of vitamin E and the oxidation is done by the quinone, converting irreversibly vitamin E into something called a semi-quinone radical. The latter is reactive, especially the gamma-tocopherol derived one, can actually increase PUFA peroxidation rather than inhibit it, and is cytotoxic.
The Semiquinone Radical of Tocopherol - PubMed
Tocopherylquinone and tocopherylhydroquinone - PubMed
In doses of say less than 5mg of a quinone taken with vitamin E, the amount of generated reactive semi-quinones/radicals is probably too small to matter, hence why there is no issue when eating liver.
This is so helpful.
I only take a couple drops of Lapodin at a time, or one drop of Kuinone, or one drop of Oxidal, so I think those are fine to take with your tocopherol products.
I think I just need to be careful with Ubiquinol, as that is 100 mg.
Thank you again for your excellent products and contributions here.
I turned 24 recently, and I've been using Kuinone every day for one month (3x 3 drops).
My wisdom tooth is starting to erupt on the left side. It's 5% erupted; a hole has formed, revealing a bit of my wisdom tooth. It's painless for now. My wisdom tooth on the right side is 90% erupted, but it took maybe two years to erupt, and I remembered that the "hole" in the gum process took a much longer time to form than it does now on my left side.
One year ago, I had an x-ray and saw that my left wisdom tooth (right in the photo) was almost lying down, so we'll see how it comes out, knowing that vitamin K2 is excellent for teeth according to the testimonials I've read here, the work of Weston Price, and the book Vitamin K2 and The Calcium Paradox which was recommended here by @Healthia and which I've read (very interesting).
Also, almost two years ago, I stayed in Thailand for one month, and following this trip, I started taking Kuinone for one month. I had seen right away effects like an increase in libido and calm + serenity. Unfortunately, I haven't felt these effects at the moment. It could be because my vitamin D levels were at max before, as I spent one month outside in sunny Thailand before taking K2, and now my D3 levels are currently only 34 ng/mL, so relatively low.
My wisdom tooth is starting to erupt on the left side. It's 5% erupted; a hole has formed, revealing a bit of my wisdom tooth. It's painless for now. My wisdom tooth on the right side is 90% erupted, but it took maybe two years to erupt, and I remembered that the "hole" in the gum process took a much longer time to form than it does now on my left side.
One year ago, I had an x-ray and saw that my left wisdom tooth (right in the photo) was almost lying down, so we'll see how it comes out, knowing that vitamin K2 is excellent for teeth according to the testimonials I've read here, the work of Weston Price, and the book Vitamin K2 and The Calcium Paradox which was recommended here by @Healthia and which I've read (very interesting).
Also, almost two years ago, I stayed in Thailand for one month, and following this trip, I started taking Kuinone for one month. I had seen right away effects like an increase in libido and calm + serenity. Unfortunately, I haven't felt these effects at the moment. It could be because my vitamin D levels were at max before, as I spent one month outside in sunny Thailand before taking K2, and now my D3 levels are currently only 34 ng/mL, so relatively low.
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youngsinatra
Member
@haidut
I really like your K2 in ethanol/SFA. I previously tried Thorne‘s K2 on the scrotum but it did not really absorb well and it just caused oily balls and also caused some testicular pain after a while. Maybe it caused a unfavorable change in testicular fatty acid composition?
Your product rapidly dries and absorbs when used topically on the scrotum. Have noticed a boost in libido and muscle strength in the gym. Also no testicular pain or discomfort anymore.
I use 5 drops. (10mg)
I really like your K2 in ethanol/SFA. I previously tried Thorne‘s K2 on the scrotum but it did not really absorb well and it just caused oily balls and also caused some testicular pain after a while. Maybe it caused a unfavorable change in testicular fatty acid composition?
Your product rapidly dries and absorbs when used topically on the scrotum. Have noticed a boost in libido and muscle strength in the gym. Also no testicular pain or discomfort anymore.
I use 5 drops. (10mg)
I want to try this for insomnia. Has anyone tried it for that and if so, how much?
It’s just a good idea to take them together but you don’t have to of course
Post in thread 'Androgens (DHT, T) Treat Prostate Cancer, Especially When Combined With Vitamin D'
Androgens (DHT, T) Treat Prostate Cancer, Especially When Combined With Vitamin D
«You can take K2 on its own, there is no need to take with D3. It's just that if you take with D3, it will help put the absorbed calcium into the bones and not the soft tissues»
Kuinone is the brand name of Haidut’s (vitamin) K2 and Calcirol is what his (vitamin) D3 is called
Post in thread 'Androgens (DHT, T) Treat Prostate Cancer, Especially When Combined With Vitamin D'
Androgens (DHT, T) Treat Prostate Cancer, Especially When Combined With Vitamin D
«You can take K2 on its own, there is no need to take with D3. It's just that if you take with D3, it will help put the absorbed calcium into the bones and not the soft tissues»
Kuinone is the brand name of Haidut’s (vitamin) K2 and Calcirol is what his (vitamin) D3 is called
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