1. NewACC

    Aspirin Cause Antiserotonine Effect Only At Low Doses (My Vision of the Non-Linear Dose-Dependent Antiserotonin Effect of Aspirin)

    Dear peats! As you all know, serotonin has a direct aggregative coagulant effect through the 5-ht2 family of receptors. And so, aspirin has the strongest antiplatelet effect at doses below 325 mg. We also know that aspirin has the most potent beneficial effect on tyrosine hydroxylase at a...
  2. haidut

    Metergoline - Liquid Serotonin Antagonist For Lab/R&D

    This chemical metergoline is a very interesting substance and is a continuation of my search for chemicals that combine several beneficial characteristics into a single molecule/entity. Metergoline belongs to the same class of drugs as bromocriptine, lisuride, cabergoline, terguride, etc...
  3. Drareg

    Neonatal Maternal Separation Alters, In A Sex-Specific Manner, The Expression Of TRH, Of TRH-Degradi

    Hypothalamic-pituitary-thyroid (HPT) axis activity is important for energy homeostasis, and is modified by stress. Maternal separation (MS) alters the stress response and predisposes to metabolic disturbances in the adult. We therefore studied the effect of MS on adult HPT axis activity. Wistar...
  4. haidut

    Glycine Lowers Tsh

    This study adds to the evidence that glycine is pro-thyroid and thus anti-stress. A single relatively low (human equivalent) dose of 600mg - 1,500mg blunted the increase of TSH due to stress. Notably, the low HED dose of ~7mg/kg was the most effective, which means 500mg - 700mg is all that is...
  5. burtlancast

    Energy Production, Diabetes, Saturated Fats, KMUD, 2011

    Download link for the audio file:
  6. Blinkyrocket

    TRH- How To Lower It, What It Is

    Ray peat briefly mentioned TRH being a reason you can have high heart rate without good thyroid function and I'm kinda surprised no ones talked about it, unless it's really rare that it's ever actually a problem, so is there anywhere that explains TRH in depth.
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