facesavant
Member
Is the energin only topical? What will happen if taken internally?EDIT (10/21/22): We changed the vitamin B1 in Energin from the thiamine Hcl to the lipophilic analog known as prosultiamine. The latter is an analog of allithiamine, and allithiamine is well-known to forum users for its high bioavailability and ability to raise levels of thiamine pyrophosphate (TPP) in muscles, brains, and other organs while the same has not been shown to occur with intake of thiamin Hcl. TPP is also a required co-factor of the enzyme pyruvate dehydrogenase (PDH), which is the rate-limiting step in the oxidative metabolism of glucose. PDH downregulation has been observed in many diseases including diabetes, obesity, cancer, dementia, MELAS, ALS, myopathies, mental disorders, infectious diseases, sepsis, etc.
Prosultiamine - Wikipedia
en.wikipedia.org
As such, the presence of porsultiamine in Energin should increase the effects associated with usage of vitamin B1. Both prosultiamine and allithiamine are naturally occurring analogs of vitamin B1, and present in high concentrations in garlic and are probably responsible for the unique smell of garlic, with Energin now smelling somewhat similar to garlic as well.
Allithiamine - Wikipedia
PSA: Change in Energin formulation (thiamine replaced by prosultiamine)
Just a quick heads up. We changed the vitamin B1 in Energin from the thiamine Hcl to the lipophilic analog known as prosultiamine. The latter is an analog of allithiamine, and allithiamine is well-known to forum users for its high bioavailability and ability to raise levels of thiamine...raypeatforum.com
EDIT (12/15/18): We changed the Energin bottle from 2 ounce to the 1 ounce size. The amount of vitamins per dose and the servings per bottle (30) stay the same. So, basically, the same product but more concentrated and thus with less liquid. Many people have asked for smaller bottles as measuring 40 drops from the 2oz bottle is tedious and with the new bottle a single serving will be only 20 drops. Also, the smaller bottle is obviously lighter and this will lower shipping costs, especially for international orders.
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Hi all,
After several weeks of experimentation, we are finally ready to start offering the B complex supplement I mentioned in my previous threads. We are calling it Energin. It is designed for topical administration. For the topical method I used a slightly modified ethanol solution, so basically the supplement is a mix of high purity B vitamins in 20% ethanol. Other than the B vitamins (all of them with greater than 98% purity) and the diluted ethanol, there is nothing else in the bottle. Here are some basic facts about the supplement.
Note: This product contains raw material(s) meant for external use only, in cosmetic or other formulations designed for such external use.
Serving size - 25 drops
Servings per container - 30
Each serving contains:
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Vitamin B1 (Prosultiamine): 25mg
Vitamin B2 (Riboflavin-5-Phosphate): 15mg
Vitamin B3 (Niacinamide): 100mg
Vitamin B5 (D-Panthenol): 50mg
Vitamin B6 (Pyridoxal-5-Phosphate): 6mg
Vitamin B7 (Biotin): 1mg
Other ingredients: add product to shopping cart to see info
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Based on a study "j." posted about a month ago, the topical absorption is over 90% for the vitamins above. The vitamins above were chosen since he has written about them in many of his articles. For the people wondering why Energin does not contain folic acid, or B12, please see this discussion:
DNA Methylation, Aging, And Cancer
If you have any questions, feel free to ask me here or send me a PM.
Thanks again for your patience.
. I take 10 drops in the morning with and extra 300 mg bentothiamine (B1), and Biotin. On days when I have a big breakfast of beef liver/kidneys I don't take Energin... B vitamins can increase adrenaline and digestion though, especially for methylators. 
