Well I have to defer to you on that one as I am not a scientist. Also thought it worth mentioning I am not a Bill Sardi proponent, and I know he has a heavily vested interest in resveratrol. That said, his info at the link above seemed interesting...Also, if I may, what is your opinion of this...
Comparative autoradiographic investigations on the tissue distribution of benfotiamine versus thiamine in mice. - PubMed - NCBI
Like I said, not a fan of benfothiamine or resveratrol. I have tried both with bad results. Regular thiamine or at best allithiamine is where it's at for me. And niacinamide of course, as it is an antagonist to resveratrol. Resveratrol is just plain evil. It is a very similar molecule to the drug Vioxx, which killed so many people and was withdrawn/banned by the FDA.