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You're likely metabolizing it very quickly either to estradiol and DHT or via the liver or both. Perhaps you'd be a better candidate for a patch? Slower release during the day.
Hans, I know everyone is different and there’s a whole ton of important variables here, but with regards to the twice a day application (one morning and one evening)…what would you recommend a good place to start for an average 30 year old hypogonadal male. 50mg x twice a day transcrotally seems quite low compared to the 150mg once a day that many people claim to be a good starting place? I prefer your logic which considers the half life. Thanks mate.
My estradiol was pretty low and estrone sulfate. ES1 was actually below the range low. DHT clearly too high especially for where my test is at. I’ll have to look into the patch. Maybe first I’ll just try non scrotal application and see what happens.
Ok, keep us updated.
I have bad vitamin a toxicity and iron overload from a previous steroid cycle that killed my adrenals , and allowed me to become vulnerable to the A overload despite not even really overdoing it. No supps. I wonder if my liver can’t handle exegenous T because it’s already messed up? And I need to handle those issues first? Could it be exegenous T wasn’t working because of existing liver issues? I understand Testosterone is generally protective for liver, but I’m sure there are some caveats in which exegenous T could worsen homeostasis and harm liver as just another additional stressor?
As per one of the studies I linked in the article, 50mg scrotal T increases T to 670ng/dl on average. Some people had a bigger increase and some a smaller one.
Have you ever done a DUTCH test to look at urinary excretions of your hormones?
I have not. Can I order it myself to do from home?
Yes, that can be done. It can be ordered from Directlabs. DUTCH complete is a good one.
Gotcha. It seems that Dutch complete has an organic acid test within it as well? On top of the typical hormones and all?
Yes, but not nearly as many markers as the complete oat test.
I see.. random but real quick question here regarding oats.. can you have low levels of sulfur in the body, but still be sulfur intolerant? How does that work? It’s the fact that you’re so low in sulfur that if you try to supplement it the detox can overwhelm ?
Maybe it's related to the excess conversation to sulfite by bacteria, which causes problems. Do you have gut issues? It could also be related to a mineral deficiency.
Bad gut issues, can hardly drink water. Liquids are really problematic. Im just trying to understand if im sulfur excess or sulfur intolerant due to a molybdenum defeciency or b vitamins.
An OAT test can help to show overgrowth of certain bacteria as well as fungus.
I haven’t, but I have some. Dutch complete is urinary? Is that fine? I’m about to order it.. I thought saliva was ideal?
Yes urine and that's what you want to see the metabolism of your hormones. It test salivary cortisol and DHEA as well.
Got it thank you. If estrogen is always low on bloods, and then on a Dutch it shows low estrogen and metabolites also is that a clear cut sign you’re actually low estrogen. You can’t really dispute that and try to still say somehow one is still low tissue estrogen can you?
