Toxic DHT: can DHT ever be too high from scrotal T?

[Miggie]

Androgens upregulate receptor's sensitivity, we are not talking about opioid receptors here.

Yes that's according to studies. So if that was real life we would expect people to run 250 mg of test and gain indefinitely. However there doesn't really seem to be an improvement in that regard, if any it slows down.

 

[Hans]

Got it thank you. If estrogen is always low on bloods, and then on a Dutch it shows low estrogen and metabolites also is that a clear cut sign you’re actually low estrogen. You can’t really dispute that and try to still say somehow one is still low tissue estrogen can you?

I'd say so yes. Most people that have low E also have low T, so I rather see it as a symptom than something to address directly. Upping DHEA and T will automatically increase E1 and E2. A very small percentage of people have very low aromatase activity.

 

[Santosh]

if any it slows down.

X amount of androgens is going to sustain Y amount of muscles consistantly, no more, no less.

You see people shrink after being on the same dose for a few months or a few years ?
How many have you seen ?
What's your sample size ?

Could it be because their natural T finally shuts down and now they need more exogenous T to make up for this decline ?
Could it be because they eat like crap and are full of endotoxins and lactic acid which are wearing down their muscle mass over time ?

 

[Miggie]

X amount of androgens is going to sustain Y amount of muscles consistantly, no more, no less.

You see people shrink after being on the same dose for a few months or a few years ?
How many have you seen ?
What's your sample size ?

Could it be because their natural T finally shuts down and now they need more exogenous T to make up for this decline ?
Could it be because they eat like crap and are full of endotoxins and lactic acid which are wearing down their muscle mass over time ?

I was referring to the gaining and this is only keeping in mind mild androgen use. If it comes to higher doses and harsher androgens it could have a negative feedback on other parts in the body. now imagine someone on harsh orals for a few months. After those few months his digestion goes to ***t so cant digest food. In that case he would shrink indeed.

Lets say person weights X and he gains 1 lb per month on 250 mgs of test. If it would up-regulate over time he would gain faster up till the point where he becomes capped out at his dose.

Shrinking will definitely occur but only on very high levels. Think pro bodybuilders where its more than just the androgen receptor thats at play. to which the 2 scenarios you wrote out could possibly play a factor in.

 

[maxpower]

Yes, I did. It took about 18 days to be delivered to eastern Europe.

What did you order DHT powder? What was your results with it ?