stoic
Member
- Joined
- Aug 21, 2020
- Messages
- 271
This is extremely interesting, clearly it deserves a dedicated thread.Well, serotonin syndrome cases are on the rise, especially the undiagnosed chronic versions of it.
Why Is Serotonin Syndrome on the Rise? - Page 2
www.medscape.comMany people may suffer from chronic serotonin syndrome
A very interesting article, which calls out the widespread usage of serotonergic drugs (usually SSRI), and argues that their widespread use may have created an "epidemic" of a chronic, milder version of the (in)famous serotonin syndrome (SS). Currently, mainstream medicine does not recognize...raypeatforum.com
Most vaccines trigger the immune response through activation of the TLR4 (endotoxin) receptor.
The science of vaccine adjuvants: advances in TLR4 ligand adjuvants - PubMed
TLR ligands are used in modern vaccine adjuvants, TLR4 ligand-based adjuvants are the most advanced in commercial vaccines. Increased understanding of TLR4 receptor-ligand interactions enables chemical synthesis and modification of new leads and our understanding of the biological/immunological...pubmed.ncbi.nlm.nih.gov
Activation of TLR4 triggers serotonin synthesis and release into the blood, amplifies serotonin effects at the cellular/receptor level, and decreases serotonin deactivation by SERT.
Toll-like receptors 2 and 4 modulate the contractile response induced by serotonin in mouse ileum: analysis of the serotonin receptors involved - PubMed
TLR2 and TLR4 signaling may modulate the spontaneous contractions and the serotonin contractile response by acting on 5-HT2, 5-HT3, 5-HT4, and 5-HT7 receptors.pubmed.ncbi.nlm.nih.govSAGE Journals: Your gateway to world-class research journals
Subscription and open access journals from SAGE Publishing, the world's leading independent academic publisher.journals.sagepub.com
This has been kind of known for years, but nobody dares to point the finger at serotonin as it is multibillion dollar industry (e.g. SSRI drugs).