Help searching for medical journals on Mrna vaccine

happycell

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Jun 25, 2014
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I’m finding that searching for specific peer reviewed medical journals is not so easy. Not everything is a simple google search.
I’m trying to cite journals that conclude various side effects from MRNA are significant enough to warrant a ‘precaution’.
While there are plenty of lectures and vids from credible sources, they won’t hold up under scrutiny as a published medical journal would.

Common side effects might include:
  • That spike protein production is unpredictable in time and quantity between individuals.
  • That spike protein can concentrate in different organs
  • Significant Blood clot risk with Pfizer
  • That mrna can exacerbate existing auto-immune conditions.
  • ADE !
Here’s what I’ve stumbled across so far, and correct me if I’m wrong about the conclusions…
 

BTCMom

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Oct 6, 2021
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Most medical journals will be behind a paywall. Libraries pay 10s of thousands of $ to have access to professional journals. Most medical libraries will require you to be a student or faculty member at the school to use them, because this is part of their contract with the database vendors who sell bundled subscriptions.

If you have the citation, you can ask your local public library to use interlibrary loan to get the article. As public library though the chance of getting the request filled is not great. If one of your local university libraries allows local to pay a fee for library use, it might be worth it. Sometimes they will allow you to use interlibrary loan services (but not likely they will give you full access to the research databases). Some states have state medical libraries that may be able to help.

The only other way is if you have a friend willing to use their university library privilege, but they will be breaking university rules and if caught may be expelled - likelihood very low.

All of this may be different in countries outside the U.S.
 

Mauritio

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Feb 26, 2018
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Bump

Especially interested in the often mentioned animal studies with long term side-effects using the MRNA technology.
 

Mauritio

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Here is something :

"While preclinical studies have generated great optimism about the prospects and advantages of mRNA-based vaccines, two recent clinical reports have led to more tempered expectations22,91. In both trials, immunogenicity was more modest in humans than was expected based on animal models, a phenomenon also observed with DNA-based vaccines171, and the side effects were not trivial. We caution that these trials represent only two variations of mRNA vaccine platforms, and there may be substantial differences when the expression and immunostimulatory profiles of the vaccine are changed. Further research is needed to determine how different animal species respond to mRNA vaccine components and inflammatory signals and which pathways of immune signalling are most effective in humans."

(mRNA vaccines — a new era in vaccinology)
 

Mauritio

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Here is an interesting human study on the mRNA technology pre-covid19.
It all reads relatively harmless until you get to the unsolicited adverse events that are "deemed unrelated to the vaccine ". How did they conclude it was unrelated. I'm not saying it is related ,but how would they know?
Btw the study was carried out mostly by moderna employees.

"Three severe unsolicited AEs (back pain, tonsillitis, ruptured ovarian cyst) and 2 SAEs (cholecystitis, ruptured ovarian cyst) were reported and deemed unrelated to vaccination. No AESIs or cases of new onset of chronic illness were reported.

ID vaccination was associated with high rates of solicited AEs (eTable 2, supplemental materials), and the sponsor elected to discontinue enrollment of these cohorts."

"Five reported SAEs were deemed unrelated to vaccination: unintentional firearm-related death, testicular cancer, pancreatitis, facial cellulitis, and exacerbated hypertension. No AESIs or cases of new onset of chronic illness were reported."
 

Mauritio

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"Male CD-1 mice received 6 μg formulated H10 mRNA either IM or ID. Following IM administration, the maximum concentration (Cmax) of the injection site muscle was 5,680 ng/mL, and the level declined with an estimated t1/2 of 18.8 hr (Table 1). Proximal lymph nodes had the second highest concentration at 2,120 ng/mL (tmax of 8 hr with a relatively long t1/2 of 25.4 hr), suggesting that H10 mRNA distributes from the injection site to systemic circulation through the lymphatic system. The spleen and liver had a mean Cmax of 86.9 ng/mL (area under the curve [AUC]0–264 of 2,270 ng.hr/mL) and 47.2 ng/mL (AUC0–264 of 276 ng.hr/mL), respectively. In the remaining tissues and plasma, H10 mRNA was found at 100- to 1,000-fold lower levels."

Screenshot_20211121-183653_Chrome.jpg

 

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