Arrade
Member
- Joined
- Apr 29, 2018
- Messages
- 1,496
Are you ignorant of the fact that skin application often leads to absorption into the blood stream fairly often?@Arrade LOL Are you freakin trolling? You are refering to oral administration of Ket, topically it does not have those effects bro. Were's your head at?
"... ketoconazole is an androgen receptor antagonist, competing with androgens such as testosterone and dihydrotestosterone (DHT) for binding to the androgen receptor. This effect is thought to be quite weak however, even with high oral doses of ketoconazole.[34]"
[34] https://www.ncbi.nlm.nih.gov/pubmed/1526623
"It should be noted, however, that the dose of ketoconazole required for 50% occupancy of the androgen receptor is not likely to be achieved in vivo, at least in plasma."
Did you see my studies showed it had effects in lowering testosterone in men? It also raised estrogen?
I myself said it was weak but it has shown to have a statistically significant effect and is probably the reason it works for hairloss