Supplemental Riboflavin (B2) And Insomnia

Discussion in 'B2' started by postman, Aug 31, 2019.

  1. postman

    postman Member

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    I recently began experimenting with vitamin b2 supplementation and I've had some great results concerning cognitive function, memory and learning, sexual function etc.

    But it also seems to make it very hard to fall asleep. Why is this and how could I fix it?

    Someone else posted this Ray Peat quote on the forum:
    So maybe this is why. Does anyone know of any riboflavin supplement/powder that is not produced via this method or is not sourced from corn starch?
     
  2. charlie

    charlie The Law & Order Admin

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    Have you tried a smaller amount in the morning only? I think sometimes some B-vitamins can cause sleeping issues when taken in the afternoon.
     
  3. Cirion

    Cirion Member

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    So.... maple syrup? =D
     
  4. Frankdee20

    Frankdee20 Member

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    Regular B2 or the 5P ?
     
  5. ecstatichamster

    ecstatichamster Member

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    Others have reported the same issue with larger doses of B2. I haven’t found it to be a problem myself but others have.
     
  6. somuch4food

    somuch4food Member

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    Which form? Which brand? I tried a prenatal with higher dosage and mostly not activated and it gave me more energy, but I had a hard time sleeping which is not great (it had 25 mg of riboflavin per capsule and I was taking one in the morning only).

    Then, I switched to an activated prenatal with lower dosage and I feel like it calms me down instead (to the point that I'm sleepy, a good thing if you ask me since I haven't slept well in the last few years). It's got 1.67mg of 5P.

    I don't know whether my adverse reaction is due to contamination, the vitamin forms or simply too much Bs. Just chiming in to share my personal experience.
     
  7. Tarmander

    Tarmander Member

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    Riboflavin causes a building of glycogen in the muscles, niacinamide causes a release of the glycogen so you could try combining the two.

    I have found when I start using high doses of B2 I get better sleep at first and then as time goes on worse sleep and mounting anxiety. You have to use small amounts timed around meals.
     
  8. OP
    postman

    postman Member

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    interesting, what brand are you taking?
     
  9. jb116

    jb116 Member

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    B2 plays a big role in supporting methylation, specifically taking electrons from B3 to create methylfolate. It's important but obviously can be disruptive to times of rest and sleep.
     
  10. somuch4food

    somuch4food Member

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    Thorne basic prenatal.

    Do you mean that too much methylation disrupt sleep?
     
  11. jb116

    jb116 Member

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    Exactly
     
  12. charlie

    charlie The Law & Order Admin

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    What is the best way to approach that?
     
  13. jb116

    jb116 Member

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    First, make an effort to take all B's if there is the decision to supplement, unless there is clinical evidence of one of them specifically being actually deficient.
    Also use physiological doses unless you are specifically trying to fix a specific health issue. The final thing that can help is using supplement B's starting earlier in the day.
    This will ensure that closer to bed time the numerous metabolic activities associated with all B's are less active at that time and you can wind down.
     
  14. charlie

    charlie The Law & Order Admin

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    Thank you sir, much appreciated. :hattip
     
  15. OP
    postman

    postman Member

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    I contacted a manufacturer and asked them if it was sourced from corn, this was their reply

     
  16. somuch4food

    somuch4food Member

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    Maybe, you should ask them what feeds the fungus that produces it.
     
  17. OP
    postman

    postman Member

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    Well I don't have an allergy to corn or anything like that, I was concerned about if the riboflavin was made by oxidizing corn starch with sulfuric acid or whatever it was Ray Peat said. But maybe that quote is from 40 years ago, who knows.
     
  18. accelerator

    accelerator Member

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    How much B2 were you taking and in what form?
     
  19. ecstatichamster

    ecstatichamster Member

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    Dr Peat has repeatedly warned of possible allergy to riboflavin and this fungal or bacterial production process explains that I think.
     
  20. Tarmander

    Tarmander Member

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    riboflavin. Not sure exactly, but I can handle 100-200mg pretty easily now...but as you get up to 1grm per day it gets rough.
     
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