vitamin b2

A rather fascinating case study/report, which, despite its misleading and convoluted description, suggests yet again that motor neuron diseases such as Amyotropic Lateral Sclerosis (ALS) are nothing but severe mitochondrial/energetic dysfunction that can often be remediated quite easily. This is...

I recently began experimenting with vitamin b2 supplementation and I've had some great results concerning cognitive function, memory and learning, sexual function etc. But it also seems to make it very hard to fall asleep. Why is this and how could I fix it? Someone else posted this Ray Peat...

Cholesterogenesis to Steroidogenesis: Role of B2 in the Biosynthesis of D From Cholesterogenesis to Steroidogenesis: Role of Riboflavin and Flavoenzymes in the Biosynthesis of Vitamin D From Cholesterogenesis to Steroidogenesis: Role of Riboflavin and Flavoenzymes in the Biosynthesis of...

There are few reliable treatments of the so-called "age spots" officially known as lipofuscin. Ray has written about the role of iron, PUFA and estrogen in the formation of this skin pigment and has suggested that vitamin E may be one possible treatment. Now we can add vitamin B2 to the list of...

Hopefully this won't spur another war on words as the previous discussion on the circadian clock. This study found that the coenzyme FAD (a derivative of riboflavin) control the circadian clock in a light-independent manner. To make the matters even more "metabolic" so to speak, the levels of...

..and can exacerbate a deficiency, especially in large amounts. Toxicity of Glycine for Vitamin B12-Deficient Chicks.† <- Crosses like this are scary. "Twenty-eight day-old White Leghorn chicks which had been fed the vito B12-deficient diet shown in Table I from the day of hatching were used...

As the article says the therapy is not yet approved by the FDA in the US but if it works as well as it is being described then it is only a matter of time to get it available here. I am not sure I am thrilled about the UVA light used as part of the procedure, but still it is an impressive...

I posted a few studies recently showing that riboflavin has an anti-endotoxin effect and protects from colonic inflammation. Apparently, in addition to its direct effects on the TLR4 receptor, riboflavin is capable of actually changing the microbiome composition when used as a supplement. It...

Even though this is officially considered an epidemiological study, it was a lot more controlled than that. The patients were given vitamin supplementation and compliance was enforced as much as possible. So, you can call this an open label trial. And given that the population studied was one...

I am posting this simply because I thought it is a cool study that illustrates the electrical versatility of electron withdrawing agents like the quinones, riboflavin, and even NAD. Harvard's battery tech takes cues from vitamin B2 "...A team of Harvard scientists on a quest to find an organic...

This is a very good study IMO because it highlight that, as Ray has said many times, the microbial balance in the colon depends on the redox state of the organism. So, the solution to microbiome imbalance is probably not to ingest cupsfuls of bacteria but to improve the oxidative state of the...

Has anyone had good or bad results with supplemental vitamin B2? Like to share your experiences? @haidut, do you know how R5P compares to regular riboflavin as to dosage?

Continuing a long and distinguished tradition of simultaneous disdain for OTC vitamins and approval for "drugs" using vitamins, the FDA has approved the topical use of vitamin B2 in the form of riboflavin '5 phosphate (R5P) as a treatment for progressive keratoconus. FDA approves Avedro’s...

I think the mechanisms of action of vitamin B2 (riboflavin) are likely to make is a possible candidate for treating several inflammatory conditions, and I posted some studies about that already. This study shows that a low dose vitamin B2 course for 4 months may be able to help conditions with...

Peat said in one of his interviews that vitamin B2, together with vitamin B1, selenium, vitamin K and CoQ10 are the most important substances for optimal mitochondrial function. I have been researching vitamin B2 and continue to be amazed at how underestimated this nutrient is both in...

Mitochondrial nutrients stimulate performance and mitochondrial biogenesis in exhaustively exercised rats. - PubMed - NCBI Abstract The aim of this study was to investigate the effects of a combination of nutrients on physical performance, oxidative stress and mitochondrial biogenesis in...

@haidut has mentioned PDH many times and it is a very important enzyme, which leads me to believe it's cofactors are very important too. Personally, if I go without lipoic acid I get excessive urination and my neuropathy flairs a bit. We all know how important Magnesium and niacinamide are. I...

There have been several request to remove vitamin from the Energin formulation and also not much focus on its effects by us forum members. However, this older study, which also cites other studies, reminds us that thiamine (B1) and riboflavin (B2) are ESSENTIAL / MANDATORY for the liver to be...

I was wondering what might be good dosages of thiamine, riboflavin, niacinamide, pyridoxine, and biotin. I currently take the following and was wondering if the doses are OK: (I recently stopped for a few days then restarted as I find I feel better when I take them) thiamine 100mg riboflavin...

I'm starting some high-dose vitamin B2 because there are studies showing a significant proportion of migraineurs getting significant improvements from high dose B2 (eg 400mg/day), with some improvement after one month and more after 3 months. I have not read any such recommendation from Peat. I...