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  1. K

    Kill Toxoplasmosis for good

    Identification of compounds that suppress Toxoplasma gondii tachyzoites and bradyzoites https://pubmed.ncbi.nlm.nih.gov/28609444/ Drug treatment for toxoplasmosis is problematic, because current drugs cannot eradicate latent infection with Toxoplasma gondii and can cause bone marrow toxicity...
  2. haidut

    Fasting causes aging by energy depletion, vitamin B2 can stop it

    Well, if this title does not rile up the fasting crowd, I don't know what will:-) Aside from that controversy, it is actually a great study that not only suggests a dirt cheap and widely available option for retarding aging, but once again demonstrates that stress (e.g. fasting) directly causes...
  3. Hans

    How to protect yourself against exercise-induced endotoxin absorption

    Endotoxin can significantly negatively affect your health, from chronic low-grade inflammation, joint degeneration, organ inflammation and dysfunction, brain degeneration, insulin resistance, etc. Most people know that gut dysbiosis can increase endotoxin production and absorption into the body...
  4. B

    Can Riboflavin Increase Cholesterol? Experiences With Riboflavin Please?

    I have always had very low cholesterol, and the necessity of taking thyroid meds has lowered it further. Various ways have been reported to increase cholesterol. The typically suggested methods to increase cholesterol include consuming extra cholesterol and consuming extra sugar. I found only...
  5. Recoen

    Elliot Overton- TTFD And GSH

    “Why are some people unable to tolerate the TTFD form of thiamine? Did you know that TTFD temporarily depletes glutathione? In this short series, we will be examining some of the potential reasons why certain individuals experience negative reactions and side effects from TTFD supplementation...
  6. haidut

    Some ALS Cases May Be Cured By Vitamin B2 (riboflavin)

    A rather fascinating case study/report, which, despite its misleading and convoluted description, suggests yet again that motor neuron diseases such as Amyotropic Lateral Sclerosis (ALS) are nothing but severe mitochondrial/energetic dysfunction that can often be remediated quite easily. This is...
  7. postman

    Supplemental Riboflavin (B2) And Insomnia

    I recently began experimenting with vitamin b2 supplementation and I've had some great results concerning cognitive function, memory and learning, sexual function etc. But it also seems to make it very hard to fall asleep. Why is this and how could I fix it? Someone else posted this Ray Peat...
  8. haidut

    Riboflavin, Oxygen And UV Light As A Treatment For Myopia

    I posted about riboflavin a few months go in regards to treating another eye condition. This new study found that riboflavin may also be effective as a combination treatment of myopia. Novel cross-linking application for low myopia shows promise "...This new application of corneal...
  9. haidut

    Vitamin B2 (riboflavin) Reduces Lipofuscin, May Extend Lifespan

    There are few reliable treatments of the so-called "age spots" officially known as lipofuscin. Ray has written about the role of iron, PUFA and estrogen in the formation of this skin pigment and has suggested that vitamin E may be one possible treatment. Now we can add vitamin B2 to the list of...
  10. haidut

    Vitamin B2 (FAD) (not Light) May Control The Circadian Clock

    Hopefully this won't spur another war on words as the previous discussion on the circadian clock. This study found that the coenzyme FAD (a derivative of riboflavin) control the circadian clock in a light-independent manner. To make the matters even more "metabolic" so to speak, the levels of...
  11. Amazoniac

    Interactions Of Thiamine, Riboflavin, And Other B-vitamins

    INTERACTIONS OF THIAMIN, RIBOFLAVIN, AND OTHER B‐VITAMINS "[W]hile lack of nicotinic acid dominates the picture, pellagra is in truth a disease of multiple deficiencies-nicotinic acid, protein, riboflavin, and perhaps haemopoietic factors." "Excess leucine in the diet may antagonize the...
  12. haidut

    Riboflavin Therapy Can Reverse Myopia

    As the article says the therapy is not yet approved by the FDA in the US but if it works as well as it is being described then it is only a matter of time to get it available here. I am not sure I am thrilled about the UVA light used as part of the procedure, but still it is an impressive...
  13. haidut

    Vitamin B2 (riboflavin) Positively Modulates The Microbiome

    I posted a few studies recently showing that riboflavin has an anti-endotoxin effect and protects from colonic inflammation. Apparently, in addition to its direct effects on the TLR4 receptor, riboflavin is capable of actually changing the microbiome composition when used as a supplement. It...
  14. haidut

    Vitamin B2 (riboflavin) Is Endotoxin (LPS / TLR4) Antagonist

    This is just a follow up on the recent post on both riboflavin and vitamin D. Vitamin B2 Remarkably Effective Against Endotoxin, Sepsis, And Other Bacterial Infections https://raypeatforum.com/community/threads/vitamin-d-is-endotoxin-lps-tlr4-antagonist-may-treat-lps-linked-conditions.12060/...
  15. haidut

    Harvard Creates Batteries Using Quinones And Riboflavin

    I am posting this simply because I thought it is a cool study that illustrates the electrical versatility of electron withdrawing agents like the quinones, riboflavin, and even NAD. Harvard's battery tech takes cues from vitamin B2 "...A team of Harvard scientists on a quest to find an organic...
  16. haidut

    Riboflavin As The Next Generation Prebiotic Supplement

    This is a very good study IMO because it highlight that, as Ray has said many times, the microbial balance in the colon depends on the redox state of the organism. So, the solution to microbiome imbalance is probably not to ingest cupsfuls of bacteria but to improve the oxidative state of the...
  17. Drareg

    Riboflavin, A Testosterone 5 Alpha-reductase Inhibitor

    Can anyone access the full study? Sounds Interesting.I didn't have a great experience of Riboflavin when I took it a while back. Riboflavin, a testosterone 5 alpha-reductase inhibitor. - PubMed - NCBI
  18. haidut

    Vitamin B2 (R5P) Approved As A Drug For Treating Keratoconus

    Continuing a long and distinguished tradition of simultaneous disdain for OTC vitamins and approval for "drugs" using vitamins, the FDA has approved the topical use of vitamin B2 in the form of riboflavin '5 phosphate (R5P) as a treatment for progressive keratoconus. FDA approves Avedro’s...
  19. haidut

    Vitamin B2 May Be Effective Against (osteo) Arthritis

    I think the mechanisms of action of vitamin B2 (riboflavin) are likely to make is a possible candidate for treating several inflammatory conditions, and I posted some studies about that already. This study shows that a low dose vitamin B2 course for 4 months may be able to help conditions with...
  20. haidut

    Vitamin B2 Remarkably Effective Against Endotoxin, Sepsis, And Other Bacterial Infections

    Peat said in one of his interviews that vitamin B2, together with vitamin B1, selenium, vitamin K and CoQ10 are the most important substances for optimal mitochondrial function. I have been researching vitamin B2 and continue to be amazed at how underestimated this nutrient is both in...