I’m having really good results with Lapodin. I’m 55 and going through menopause. I’ve been taking Lapodin for over a month now.
The first thing I noticed was a reduction in hot flashes – after taking only 5 drops a day. I still ‘flush’ sometimes – but it’s seems to be linked to emotions or low blood sugar. I also felt hot all the time – in an uncomfortable way, which has completely gone away.
I’ve had problems with a high heart rate for years – my resting rate is usually 100. Using 12 drops at one time, I’ve experienced my heart rate going from 104 to 92 within 20 minutes. My resting rate now is typically 88 to 92.
If I take the full dose (24 drops – I spread it out over the day) I sleep better.
But in conjunction to Lapodin I have to take extra magnesium (I use Epsom salts dissolved in water on my skin – it’s very unscientific – I have no idea how much I’m getting). I also have to keep up with enough calories.
If I drink too much caffeine my heart rate will go back to 100, or if I'm nervous my heart rate will go up.
Thanks so much for making this Haidut – it’s been really really helpful.
I noticed in your pubmed listings that the emodins can inhibit fibrosis and inflammation, specifically in the heart and lungs. Could Lapodin help with cystic fibrosis since that is mainly lung inflammation and fibrosis in other organs? Seems like it would be beneficial.
....There is a study on using 5-HT2B antagonists like cypro and lisuride for fibrotic conditions....
Here are links to studies about serotonin (5-HT2B) antagonists reducing fibrosis in heart, liver, and lung respectively:
5-HT2B receptor antagonists inhibit fibrosis and protect from RV heart failure. - PubMed - NCBI
5-HT2B receptor antagonists inhibit fibrosis and protect from RV heart failure.
Ketanserin, a serotonin 2A receptor antagonist, alleviates ischemia-related biliary fibrosis following donation after cardiac death liver transplan... - PubMed - NCBI
Ketanserin, a serotonin 2A receptor antagonist, alleviates ischemia-related biliary fibrosis following donation after cardiac death liver transplantation in rats.
Modulation of bleomycin-induced lung fibrosis by serotonin receptor antagonists in mice. - PubMed - NCBI
Modulation of bleomycin-induced lung fibrosis by serotonin receptor antagonists in mice.
I feel that this is an underrated product. I mean, look at that research! Incredible stuff, here, and with what we know about quinones, it's probably doing so much more.
@ejalrp maybe try using a smaller dose?
I rubbed 2 drops in my scalp. I felt really good for a few seconds like I just took an aspirin. 15 minutes later, I had a bowel movement. This is typical in my experience with this supplement, but I have inflammatory bowel disease, so it might come with the territory. It was kind of loose but not watery. And all of my bowel movements have been very well-formed, tending slightly towards constipation for the past month at least. I'm not sure I'm a big fan of this effect, lol, but if I plan things right, it can be a good thing. I sure could use a decrease on my endotoxin burden. Maybe I will become tolerant. I'm willing to do more testing with this.
30 minutes later, I'm getting sleepy, which is always what happens to me with a reduction in stress hormones especially cortisol.
Thanks for that feedback! I concur that Lapodin is probably the most underrated supplement we sell. If I had to take 3 supplements only, Lapodin would be one of them, and if I had to take 2 only Lapodin would also be one of them. In fact, I think Oxidal and Lapodin may be the most viable supplements for long term use that do not really need any breaks. Don't get me wrong, the other supplements are also great but the steroid ones probably need a break every few months, the thyroid can be hit/miss for many people, and things like MitoLipin seem a bit specific in their effects. The Oxidal, Kuinone, and Lapodin are the most broadly acting and benign for every day use even very long term.
Please continue to keep us posted on effects from Lapodin. With the recent clinical trials using beta-lapachone I suspect those quinones are just starting to get famous :)
I totally agree about Lapodin, I would describe it as Aspirin++, as it comes to effects. It always raises my temperature and mood. If I could take only two supplement, it would probably be lapodin and taurine. I don't experience any side effects of lapodin.
Not sure about Oxidal, I think many people experience serotonin effects after long term use. No?
So you take it orally? How much? Did you you try taking it topically and the oral path gives you better results in terms of sleep quality?lapodin is one of the best things ive ever taken for having a good nights sleep
ive also been combining it with tianeptine and as soon as my head hits the pillow im gone and wake up feeling well rested.