metabolism

A remarkable study, that for some reason is not being covered by mainstream media. Considering 99% of the clinical trials for AD since 2000 have completely failed, this study should be front-page news for most mainstream outlets. I suspect mainstream media, being literally owned by the same...

A great study, which once again puts metabolism in the spotlight. Many studies have tried to discover the main biological differences between children and adults and so far none of them have discovered a "smoking gun". At the same time, multiple studies have demonstrated that children are much...

Another nail in CICO coffin: https://www.sciencedaily.com/releases/2021/07/210729143412.htm Treating obese mice with the cytokine known as TSLP led to significant abdominal fat and weight loss compared to controls, according to new research published Thursday in Science from researchers in the...

Through a ton of self experimentation I've found out that in order to increase metabolism on a high calorie diet all TLR4(endotoxin) inhibitors should be greatly reduced. And it does not really matter which ones exactly are currently saturating endotoxin receptors as antagonists, whether its...

3 1/2 minutes. A little Peaty! :thumbsup:

More evidence that yet another "incurable" condition is little more than energy deficit (due to mitochondrial dysfunction) in disguise. In this case the mitochondrial dysfunction was caused by accumulation of mitochondrial debris inside the cell, which has been repeatedly shown by other studies...

Yet another study demonstrating that "aging" is nothing but a phenotype characterizing an organism with declining energy production. Since most of the cellular energy is produced in the mitochondria, another way of stating the same is that aging (and any specific disease for that matter) is a...

The study only focuses on the lymphatic system and its cells, but the principle is general and has been observed in other organ/tissue cells. The most obvious example is cancer - no matter which organ it occurs in, the tumor is composed of de-differentiated cells not unlike the stem cells from...

A study that once again illustrates the central principle of bioenergetics - structure and function cannot be separated. They are interdependent at every level. In this specific case, the "structural" pathology is muscle weakness and wasting (sarcopenia, cachexia, etc). Most doctors, when...

Another study corroborating the role of DHEA as one of the "youth" hormones. A recent study already demonstrated that DHEA can reverse aging of the human immune system, which usually goes hand in hand with lower cortisol and improved metabolism. The proven anti-cortisol effects of DHEA are...

A seemingly contradictory title, but only to people who are not aware of the so-called "obesity paradox". As I have mentioned in the past, usage of the word "paradox" usually implies a very inconvenient truth that threatens the profits of one or more branches of mainstream medicine. In this case...

Hi everyone, im quite new to this forum, but already found a some great knowledge here. Althought im not convinced to go full peaty-style, i think i can use some of this wisdom to better my life. To the point. I recently did a hormone blood tests and found out that i have high prolactin (could...

The dogma that PD is just a simple dopamine deficiency manifesting in genetically vulnerable individuals is quickly becoming untenable. It is well-known among clinicians that administering dopamine precursors such as L-Dopa, or selective dopamine agonists such as pramipexole has limited...

Just a quick post on a study, which claims to have established a reliable method for inducing bipolar disorder in an animal model. This reliable method consists simply of administering a low-dose of a mitochondrial inhibitor. More specifically, an inhibitor of complex I of the electron transport...

A very interesting study, which demonstrates the unique synergy between glucose and vitamin B3 in treating deficiencies of function in Complex I & II of the electron transport chain (ETC). Deficiencies on those metabolic steps are the most common causes for the wide varieties of debilitating...

I'm eating 400-500g of sugar and 200-250g of protein every day. Around 3000 kcal daily. All good quality, Peaty foods. Oranges, raisins, milk, cheese, organ meats. I'm eating every hour or so. Yet I can't handle even the slightest metabolic boost. 100mg of caffeine, 50mg of niacinamide, 150mg...

Not many studies on this topic, but here is one that will hopefully satisfy my critics who keep complaining that there is no evidence for the anti-metabolic, pro-hibernation effects of PUFA. Apparently, PUFA is sought after by hibernating animals (but even they consume it within very tightly...

The bad news for PUFA has been accumulating for decades, yet public health authorities continue to claim that type of fat is "essential". Whatever indirect admissions of the pathological role of PUFA in both chronic and acute/infectious diseases is given to the public, is usually confined to the...

I have noticed some people just always have friends, and they don't do anything special or specific to make or keep them. Sometimes it's just neighborhood kids, workplace, schools, etc. -- and often it just naturally happens. I find it disheartening that some say that "making" or "finding"...

Hello friends of metabolic health Georgi @haidut mentions a study in a danny roddy podcast (iirc) that rats with beanies or a sweater are more intelligent/ solve a rat labyrinth faster. I am now searching this for like a week, and i can not find it. IF PLEASE SOMEONE CAN TELL ME WHERE I CAN...