metabolism

Hello! Im interested in the evolution of metabolic processes. I have found academic books which are focused on the very minute, but nothing that would be useful to me. Does anyone have any recommendations? I was looking at Nick Lane's vital question. Mae-Won Ho? Gerald Pollack? Ling? I am...

I just did a post on the role of reduced glucose metabolism, lower pyruvate/NAM/NAD and elevated lactate in the pathogenesis of glaucoma. Just minutes later, another study popped up in my newsfeed. Namely, a study that demonstrates the exact same metabolic disturbances as the main drivers of...

As many of my readers know, aging men can also experience the equivalent of menopause and doctors informally call that state "andropause". Its official name is age-related hypogonadism and most of that hypogonadism is of the "secondary" type - i.e. the gonads appears to be in fine shape but for...

Almost 25 years ago, Dr. Peat himself wrote a 2-article series in which he outlined arguments in favor of the hypothesis that aging and Alzheimer Disease (AD) are just examples of a more and less systemic sign respectively of declining energy production, and that curing one would lead to a cure...

A hugely popular tenet of the "rate of living" theory is that the higher the metabolic rate the more reactive oxygen species (ROS) an organism produces. ROS elevation has already been implicated in a host of chronic disease including diabetes, CVD, cancer, neurological conditions and even mental...

A few weeks ago, I posted about a human study demonstrating reversal of age-related vision decline by staring at a red light for just a few minutes a day. The mechanism of action proposed in that study had to do with improved mitochondrial function and energy production. Now, it seems another...

On a low A diet I have less energy, can't sleep, have oily and worse skin, but my temps are higher between meals. I found I have to eat liver daily. I get great energy from it, sleep perfectly and have much better skin. But I always find it makes my temps drop faster between meals. Is this...

An older study, but some great information in there. Not only does it call attention to the fallacy of progesterone being nothing more than a "sex" hormone, but it also warns about the fallacy of equating the synthetic progestins with bioidentical progesterone. At least, when it comes to...

Hi all, I recently posted a thread here: (Feeling Terrible at 22) where I basically listed all my symptoms and recieved some amazing advice for my metabolism, overall dietary health etc. I suggest reading this post first to get an insight into my lifestyle and health. (TL-DR; I basically...

Anybody have a good source for a personal Ultrasound Therapy Device? I have a minor bone bruise that I want to give one a shot on.

So dear all - questions questions questions....theories theories theories....don't we all just love em!!! Would really appreciate any help and input here from any and all who find the topics around Peat, Fat gain, and metabolism interesting. A bit of background. I come from a varied past of...

Yet another study demonstrating the crucial role of oxidative metabolism (OXPHOS) in a chronic degenerative condition considered largely genetic in origin. Just as importantly, the study corroborates findings from other recent reports/experiments demonstrating that the presence of cellular...

Live high:train low increases muscle buffer capacity and submaximal cycling efficiency - PubMed Showing intermittent time in altitude around 3000m having benefits ,e.g. less oxygen consumption . So even just a few hours every day at high altitude can have a good effect. Metabolic and work...

I had had health issues before and I found Ray Peat's works. And ever since I started implementing anything that is pro metabolic, my physiology and mental state have been improving. Beside that, I noticed my test in music changed drastically. Before, I was more into modern musics that are...

One of the key features of aging is the decline in mitochondrial function (metabolism), and that fact is widely recognized even by mainstream medicine. However, doctors still claim that the relationship between metabolic decline and aging has not be elucidated and a causative link cannot be...

The title of the popular press article is kind of the reverse of mine - i.e. cancer cells evade treatment by blocking energy production in immune cells (T-cells). However, my title still holds since the actual study did show that restoring energy production in T-cells restores the effectiveness...

I wanted to share this amazing gut protocol that I have been on for the last few months (results below) I am in a unique position as a type 1 diabetic in that my pancreas produces little to no insulin on its own. This gives me an insight into what supplements and herbs do to insulin needs in...

This study was sent to me by one of my Twitter followers. In some of my past interviews/podcasts, I did mention isolated published case studies, as well as anecdotal medical reports of even advanced cases of AD getting rapidly reversed by micro-dosing regimens using lithium salts such as...

As it seems, not all hope is lost when it comes to mainstream medicine. Just a few days ago I posted about a landmark human study with AD demonstrating that the a low daily dose of the cheap, unpatentable chemical methylene blue (MB) may stop AD. LSD may do the same, and both MB and LSD likely...

Yet another study demonstrating the remarkable parallels between the decline in function (metabolism) and the structural abnormalities that occur not only in specific pathologies such as AD but also in the generalized degradation known as "aging". FDA currently does not recognize aging as a...