metabolism

  1. rothko

    Recommendations for Books on Evolution of Metabolism

    Hello! Im interested in the evolution of metabolic processes. I have found academic books which are focused on the very minute, but nothing that would be useful to me. Does anyone have any recommendations? I was looking at Nick Lane's vital question. Mae-Won Ho? Gerald Pollack? Ling? I am...
  2. haidut

    Reduced pyruvate and/or increased lactate drive heart failure

    I just did a post on the role of reduced glucose metabolism, lower pyruvate/NAM/NAD and elevated lactate in the pathogenesis of glaucoma. Just minutes later, another study popped up in my newsfeed. Namely, a study that demonstrates the exact same metabolic disturbances as the main drivers of...
  3. haidut

    Low energy production (glucose metabolism) may cause andropause

    As many of my readers know, aging men can also experience the equivalent of menopause and doctors informally call that state "andropause". Its official name is age-related hypogonadism and most of that hypogonadism is of the "secondary" type - i.e. the gonads appears to be in fine shape but for...
  4. haidut

    The Cure For Aging Might Be The Cure For Alzheimer’s

    Almost 25 years ago, Dr. Peat himself wrote a 2-article series in which he outlined arguments in favor of the hypothesis that aging and Alzheimer Disease (AD) are just examples of a more and less systemic sign respectively of declining energy production, and that curing one would lead to a cure...
  5. haidut

    Low, Not High, Metabolism Creates Oxidative Stress

    A hugely popular tenet of the "rate of living" theory is that the higher the metabolic rate the more reactive oxygen species (ROS) an organism produces. ROS elevation has already been implicated in a host of chronic disease including diabetes, CVD, cancer, neurological conditions and even mental...
  6. haidut

    Red Light Therapy For Parkinson Disease (PD) Begins Human Trials

    A few weeks ago, I posted about a human study demonstrating reversal of age-related vision decline by staring at a red light for just a few minutes a day. The mechanism of action proposed in that study had to do with improved mitochondrial function and energy production. Now, it seems another...
  7. J

    Eating Liver Makes Me Feel Cold More Often And Faster, Why?

    On a low A diet I have less energy, can't sleep, have oily and worse skin, but my temps are higher between meals. I found I have to eat liver daily. I get great energy from it, sleep perfectly and have much better skin. But I always find it makes my temps drop faster between meals. Is this...
  8. haidut

    Progesterone - Not A Sex Hormone, But A Systemic Health Hormone

    An older study, but some great information in there. Not only does it call attention to the fallacy of progesterone being nothing more than a "sex" hormone, but it also warns about the fallacy of equating the synthetic progestins with bioidentical progesterone. At least, when it comes to...
  9. JazTee

    Ehlers-Danlos Syndrome Help?

    Hi all, I recently posted a thread here: (Feeling Terrible at 22) where I basically listed all my symptoms and recieved some amazing advice for my metabolism, overall dietary health etc. I suggest reading this post first to get an insight into my lifestyle and health. (TL-DR; I basically...
  10. Scott Andrew

    Ultrasound Therapy Device?

    Anybody have a good source for a personal Ultrasound Therapy Device? I have a minor bone bruise that I want to give one a shot on.
  11. Harryedgar

    Fat Loss, PUFA, Estrogen Detox And Increased Metabolism

    So dear all - questions questions questions....theories theories theories....don't we all just love em!!! Would really appreciate any help and input here from any and all who find the topics around Peat, Fat gain, and metabolism interesting. A bit of background. I come from a varied past of...
  12. haidut

    Low Metabolism, Cellular Debris May Cause Huntington Disease (HD)

    Yet another study demonstrating the crucial role of oxidative metabolism (OXPHOS) in a chronic degenerative condition considered largely genetic in origin. Just as importantly, the study corroborates findings from other recent reports/experiments demonstrating that the presence of cellular...
  13. Mauritio

    High Altitude Benefits

    Live high:train low increases muscle buffer capacity and submaximal cycling efficiency - PubMed Showing intermittent time in altitude around 3000m having benefits ,e.g. less oxygen consumption . So even just a few hours every day at high altitude can have a good effect. Metabolic and work...
  14. S

    My Taste In Music Changes With Metabolic State

    I had had health issues before and I found Ray Peat's works. And ever since I started implementing anything that is pro metabolic, my physiology and mental state have been improving. Beside that, I noticed my test in music changed drastically. Before, I was more into modern musics that are...
  15. haidut

    Cardiolipin Supplementation May Reverse Signs Of Aging

    One of the key features of aging is the decline in mitochondrial function (metabolism), and that fact is widely recognized even by mainstream medicine. However, doctors still claim that the relationship between metabolic decline and aging has not be elucidated and a causative link cannot be...
  16. haidut

    Restoring Energy Production In Immune Cells Is Therapeutic In Cancer

    The title of the popular press article is kind of the reverse of mine - i.e. cancer cells evade treatment by blocking energy production in immune cells (T-cells). However, my title still holds since the actual study did show that restoring energy production in T-cells restores the effectiveness...
  17. Tarmander

    Gut Protocol For Insulin Resistance, Metabolism, And Energy

    I wanted to share this amazing gut protocol that I have been on for the last few months (results below) I am in a unique position as a type 1 diabetic in that my pancreas produces little to no insulin on its own. This gives me an insight into what supplements and herbs do to insulin needs in...
  18. haidut

    Low Dose Lithium May Stop Alzheimer’s Disease (AD) In Its Tracks

    This study was sent to me by one of my Twitter followers. In some of my past interviews/podcasts, I did mention isolated published case studies, as well as anecdotal medical reports of even advanced cases of AD getting rapidly reversed by micro-dosing regimens using lithium salts such as...
  19. haidut

    Metabolic Dysfunction Is A Primary Cause Of Aging And Its Symptom Alzheimer Disease (AD)

    As it seems, not all hope is lost when it comes to mainstream medicine. Just a few days ago I posted about a landmark human study with AD demonstrating that the a low daily dose of the cheap, unpatentable chemical methylene blue (MB) may stop AD. LSD may do the same, and both MB and LSD likely...
  20. haidut

    Increasing Metabolism May Reverse Alzheimer Disease (AD) And General Aging

    Yet another study demonstrating the remarkable parallels between the decline in function (metabolism) and the structural abnormalities that occur not only in specific pathologies such as AD but also in the generalized degradation known as "aging". FDA currently does not recognize aging as a...
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