Methylene blue makes hair completely white. Why?

[CheckMate]

Hi guys, i have noticed something strange.
When i use MB directly on my hair (4mg) before shower, keeping it 10 minutes, after 2 days i have some white hair all over my head.
And then they start to fall off, all of them.
Anyone knows why this happen?

Thanks:)

 

[S-VV]

It may be bleaching it. Methylene blue is an oxidizing agent

 

[CheckMate]

It may be bleaching it. Methylene blue is an oxidizing agent

Yes but why only few ones? and they turn completly white while others stays the same

 

[CheckMate]

@Hans, in your newsletter you said that you use mb on you hair... This never happened to you?
Thanks

 

[Hans]

@Hans, in your newsletter you said that you use mb on you hair... This never happened to you?
Thanks

This has never happened to me, but I'm doing much smaller doses than you. I added about 2mg to my spray bottle, and the bottle lasts about 30-40 days, so I'm getting about 50-67mcg per day maybe even less.

Copper is necessary for hair pigment formation, so either methylene blue depletes copper (upregulation of cytochrome c oxide) or inhibits melanogenesis.
Alternatively, serotonin is known to cause gray/white hair and MB is an MAO-A inhibitor, so perhaps that dose increases serotonin too much for you locally, which then results in whitening.
All theories here.

 

[CheckMate]

This has never happened to me, but I'm doing much smaller doses than you. I added about 2mg to my spray bottle, and the bottle lasts about 30-40 days, so I'm getting about 50-67mcg per day maybe even less.

Copper is necessary for hair pigment formation, so either methylene blue depletes copper (upregulation of cytochrome c oxide) or inhibits melanogenesis.
Alternatively, serotonin is known to cause gray/white hair and MB is an MAO-A inhibitor, so perhaps that dose increases serotonin too much for you locally, which then results in whitening.
All theories here.

Thanks so much for the reply, i'll keep doing it with lower dosage and report back.

 

[GenericName86]

This has never happened to me, but I'm doing much smaller doses than you. I added about 2mg to my spray bottle, and the bottle lasts about 30-40 days, so I'm getting about 50-67mcg per day maybe even less.

Copper is necessary for hair pigment formation, so either methylene blue depletes copper (upregulation of cytochrome c oxide) or inhibits melanogenesis.
Alternatively, serotonin is known to cause gray/white hair and MB is an MAO-A inhibitor, so perhaps that dose increases serotonin too much for you locally, which then results in whitening.
All theories here.

I'd never heard this before but this is extremely interesting. If the white/gray hair was caused by serotonin would it revert back to normal when the serotonin issue is resolved?

 

[CheckMate]

I'd never heard this before but this is extremely interesting. If the white/gray hair was caused by serotonin would it revert back to normal when the serotonin issue is resolved?

The problem Is that all the white hair after 2/3 days fall out

 

[PolishSun]

I'd never heard this before but this is extremely interesting. If the white/gray hair was caused by serotonin would it revert back to normal when the serotonin issue is resolved?

my friend's hair turns black after using MB internally, otherwise she has natural grayish brown color. But she uses it on of. Maybe MB lowers serotonin.

 

[yerrag]

Hi guys, i have noticed something strange.
When i use MB directly on my hair (4mg) before shower, keeping it 10 minutes, after 2 days i have some white hair all over my head.
And then they start to fall off, all of them.
Anyone knows why this happen?

Thanks:)

Methylene blue kills catalase-positive bacteria, and that's why it used to be used for UTI conditions (until modern pharma decided it was too cheap and too effective to make a profit off from it).

Without the catalase from such bacteria, hydrogen peroxide isn't turned into water and oxygen. Hydrogen peroxide will then bleach your hair, and it turns white as a result.

That is my guess.

 

[Hans]

I'd never heard this before but this is extremely interesting. If the white/gray hair was caused by serotonin would it revert back to normal when the serotonin issue is resolved?

It might since serotonin inhibits proper energy metabolism and if mitochondria start to work better again, hair color should come back.

 

[Hans]

Methylene blue kills catalase-positive bacteria, and that's why it used to be used for UTI conditions (until modern pharma decided it was too cheap and too effective to make a profit off from it).

Without the catalase from such bacteria, hydrogen peroxide isn't turned into water and oxygen. Hydrogen peroxide will then bleach your hair, and it turns white as a result.

That is my guess.

Interesting theory, where is the excess H2O2 coming from?

 

[yerrag]

Interesting theory, where is the excess H2O2 coming from?

That's a good question and a search tells me that:

Going gray is caused by a massive build up of hydrogen peroxide due to wear and tear of our hair follicles. The peroxide winds up blocking the normal synthesis of melanin, our hair's natural pigment.

No longer a gray area: Our hair bleaches itself as we grow older

Wash away your gray? Maybe. A team of European scientists have solved a mystery that has perplexed humans throughout the ages: why we turn gray. These researchers show in a research report published online in the FASEB Journal that going gray is caused by a massive build up of hydrogen peroxide...

www.eurekalert.org

So, is it possible that around our hair follicles there are commensal bacteria that are catalase-positive, and that these bacteria unbeknownst to us convert hydro peroxide into water and oxygen? And that putting methylene blue killed these bacteria and allowed peroxide to whiten hair and later on destroy the hair?

 

[Hans]

That's a good question and a search tells me that:

Going gray is caused by a massive build up of hydrogen peroxide due to wear and tear of our hair follicles. The peroxide winds up blocking the normal synthesis of melanin, our hair's natural pigment.

No longer a gray area: Our hair bleaches itself as we grow older

Wash away your gray? Maybe. A team of European scientists have solved a mystery that has perplexed humans throughout the ages: why we turn gray. These researchers show in a research report published online in the FASEB Journal that going gray is caused by a massive build up of hydrogen peroxide...

www.eurekalert.org

So, is it possible that around our hair follicles there are commensal bacteria that are catalase-positive, and that these bacteria unbeknownst to us convert hydro peroxide into water and oxygen? And that putting methylene blue killed these bacteria and allowed peroxide to whiten hair and later on destroy the hair?

It's possible, but why is there an excess H2O2 on the scalp. H2O2 is produced inside the cell. How does it end up on the scalp? Unless the mitochondria are damaged in a way that allows it to produce an overabundance of H2O2 or at least there is low catalase inside the cell.

 

[yerrag]

It's possible, but why is there an excess H2O2 on the scalp. H2O2 is produced inside the cell. How does it end up on the scalp? Unless the mitochondria are damaged in a way that allows it to produce an overabundance of H2O2 or at least there is low catalase inside the cell.

I don't think H2O2 ever ends up on the scalp. The mb seeps inside the follicles and the tissues surrounding the follicles. It may well interfere with the production of catalase enzyme within the cell, which you mention is another possibility aside from killing catalase-positive bacteria.

 

[Sam321]

Hi guys, i have noticed something strange.
When i use MB directly on my hair (4mg) before shower, keeping it 10 minutes, after 2 days i have some white hair all over my head.
And then they start to fall off, all of them.
Anyone knows why this happen?

Thanks:)

It turns you super saiyan.

 

[dabdabdab]

wow, thanks for sharing your experience, now we know why mb causes tiredness in a lot of people

 

[yerrag]

wow, thanks for sharing your experience, now we know why mb causes tiredness in a lot of people

I don't know how hair turning gray has a direct connection to mb causing tiredness in people, unless I missed something.

 

[dabdabdab]

I don't know how hair turning gray has a direct connection to mb causing tiredness in people, unless I missed something.

hydrogen peroxide makes you tired. it acts like free radical. it's the same component your immune system produces when you are stressed or have infection.

 

[Blossom]

Hi guys, i have noticed something strange.
When i use MB directly on my hair (4mg) before shower, keeping it 10 minutes, after 2 days i have some white hair all over my head.
And then they start to fall off, all of them.
Anyone knows why this happen?

Thanks:)

Sorry for my ignorance but might I ask what purpose applying it directly to the scalp achieves?