Treatment for COVID-19 using Methylene Blue

md_a

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Joined
Aug 31, 2015
Messages
298
Using Methylene Blue in nebulized form for treating patients with Coronavirus (Covid-19)

As COVID-19(Coronavirus) ravages the world, a quick, novel, cost effective cure for this malaise needs to be found.

Being a pulmonologist (lung specialist) in India, I have been treating pneumonia, other respiratory ailments and Tuberculosis patients (with XDR & MDR TB) for more than 42 years.

I’ve achieved remarkable success in treating my patients with Methylene Blue and with documented evidence. When used in sub lingual and nebulised form M.B. helps remarkably in clearing alveolar capillary block.

Covid causes a silent hypoxia wherein patients despite having acute hypoxia (low oxygen saturation spO2) show no clinical symptoms. Patient is not dyspnoeic in spite of having very low oxygen saturation. These soon escalate to a cytokine storm and patient goes in the irreversible phase of the respiratory distress.

Covid patients show resemblance to methemoglobinemia. MB is considered an approved drug of choice for methemoglobinemia. Additionally, M.B. has a strong antifibrotic action and is very fast acting.

Given the above presentations, Methylene Blue can be used as a treatment to all Coronavirus symptomatic patients & as a prophylactic drug to all vulnerable population. Used in low dosage (as prescribed below) it shows no significant side effects (less than 2% of patients complained of irritation in the nose/nausea for a day which subsided on its own). Given its low cost, it is also a viable regime for poorer countries like India. A number of patients(with varying levels of respiratory distress) have been treated using MB in nebulised/sub-lingual for over the course of my years of practice.

Potential Treatment regime for the novel Coronavirus (Covid-19)

Primary course of administration is in Nebulized form and Sublingually together. For patients with severe Cyanosis (oxygen levels less than 85%), IV may be required based on the clinical condition of the patient.

Administration steps as below (under medical supervision only as MB is known to be toxic in incorrect dosages)

  • 0.1% Methylene Blue to be administered as inhalation through a nebulizer (Primary line of treatment)
  • Nebulization to be given through a nasal mask
  • Sublingual administration will be as a supportive line of treatment
Administration of Methylene Blue in nebulized form

Administration of Methylene Blue in nebulized form

A person wearing a nebulizer and ideal way
Post my recommendations, a hospital in Mumbai started administering Methylene Blue through Nebulizer as well as sublingually on COVID-19 confirmed patients with positive results.

Methylene blue (Methylthioninium Chloride) is a thiazine dye & a medication. It is easily available in drug stores across India. It is safe to consume in low dosage (0.1 mg/kg in IV form) under proper medical supervision. It was the first antiseptic dye to be used therapeutically and it is present on WHO Model List of Essential Medicines. In fact, its use was widespread even before the advent of sulphonamides and penicillin. Its benefit is it rapidly arrests fibrosis which proves beneficial against virulent strains.

[Update: on why MB works]

There are multiple reasons why MB is effective; the chief is Nitric Oxide mediated reduction in inflammatory cascades in addition to inhibiting canonical inflammasomes.

Radiologically (i.e. X Ray) Covid/Swine Flu are similar & resemble any acute viral/fungal loefflers or aspiration pneumonia. Clinical distinction can be made by giving intranasal oxygen — you’d notice an improvement in normal pneumonia but not for Swine Flu or Covid-19 as these viruses would lead to alveolar capillary blockage (i.e. block ability of the lungs to operate in simple words). MB clears the blockage within 24 hours and O2 levels start improving. Covid-19 is a more virulent strain compared to H1N1 and a fast acting drug is necessitated.

Due to the clinico/pathological resemblance between H1N1 & Covid-19 — final outcome is expected to be similar post administration of MB.



(The above comparative X Rays are a part of a series. X Rays shared post consent from the patient)

Note : Some readers have questioned why it took 4 year to clear the lesions — given the state of the patient when he came to me, the chances of survival more than 6 months were less than 10% as his lung was severely damaged(X ray 1). In medical parlance, the above X Ray (X Ray 2) progress is considered a miracle.

(Will post more details about this as and when I get time — for queries please email me)

The detailed treatment regimen can be found by clicking here.

Edit 1
Note :
We continue to see very good results with Methylene Blue nebulization/sublingual administration. Given the positive results we see, we firmly believe that Methylene Blue is the cost effective treatment of choice in these trying times.
We have received complaints that some organizations/people are using Dr Golwalkars’ name to discredit Methylene Blue for their own benefits. Please note that we continue to see very good results with Methylene Blue and continue to advise its administration.
Comment below or mail me @ dr.deepak.golwalkar@gmail.com

View: https://dr-deepak-golwalkar.medium.com/treatment-for-covid-19-using-methylene-blue-d23fc5a31a4d
 

Blossom

Moderator
Joined
Nov 23, 2013
Messages
8,607
This is awesome! Thank you so much.
 

AndrewGesell

Member
Joined
Jan 13, 2021
Messages
47
Using Methylene Blue in nebulized form for treating patients with Coronavirus (Covid-19)

As COVID-19(Coronavirus) ravages the world, a quick, novel, cost effective cure for this malaise needs to be found.

Being a pulmonologist (lung specialist) in India, I have been treating pneumonia, other respiratory ailments and Tuberculosis patients (with XDR & MDR TB) for more than 42 years.

I’ve achieved remarkable success in treating my patients with Methylene Blue and with documented evidence. When used in sub lingual and nebulised form M.B. helps remarkably in clearing alveolar capillary block.

Covid causes a silent hypoxia wherein patients despite having acute hypoxia (low oxygen saturation spO2) show no clinical symptoms. Patient is not dyspnoeic in spite of having very low oxygen saturation. These soon escalate to a cytokine storm and patient goes in the irreversible phase of the respiratory distress.

Covid patients show resemblance to methemoglobinemia. MB is considered an approved drug of choice for methemoglobinemia. Additionally, M.B. has a strong antifibrotic action and is very fast acting.

Given the above presentations, Methylene Blue can be used as a treatment to all Coronavirus symptomatic patients & as a prophylactic drug to all vulnerable population. Used in low dosage (as prescribed below) it shows no significant side effects (less than 2% of patients complained of irritation in the nose/nausea for a day which subsided on its own). Given its low cost, it is also a viable regime for poorer countries like India. A number of patients(with varying levels of respiratory distress) have been treated using MB in nebulised/sub-lingual for over the course of my years of practice.

Potential Treatment regime for the novel Coronavirus (Covid-19)

Primary course of administration is in Nebulized form and Sublingually together. For patients with severe Cyanosis (oxygen levels less than 85%), IV may be required based on the clinical condition of the patient.

Administration steps as below (under medical supervision only as MB is known to be toxic in incorrect dosages)

  • 0.1% Methylene Blue to be administered as inhalation through a nebulizer (Primary line of treatment)
  • Nebulization to be given through a nasal mask
  • Sublingual administration will be as a supportive line of treatment
Administration of Methylene Blue in nebulized form

Administration of Methylene Blue in nebulized form

A person wearing a nebulizer and ideal way
Post my recommendations, a hospital in Mumbai started administering Methylene Blue through Nebulizer as well as sublingually on COVID-19 confirmed patients with positive results.

Methylene blue (Methylthioninium Chloride) is a thiazine dye & a medication. It is easily available in drug stores across India. It is safe to consume in low dosage (0.1 mg/kg in IV form) under proper medical supervision. It was the first antiseptic dye to be used therapeutically and it is present on WHO Model List of Essential Medicines. In fact, its use was widespread even before the advent of sulphonamides and penicillin. Its benefit is it rapidly arrests fibrosis which proves beneficial against virulent strains.

[Update: on why MB works]

There are multiple reasons why MB is effective; the chief is Nitric Oxide mediated reduction in inflammatory cascades in addition to inhibiting canonical inflammasomes.

Radiologically (i.e. X Ray) Covid/Swine Flu are similar & resemble any acute viral/fungal loefflers or aspiration pneumonia. Clinical distinction can be made by giving intranasal oxygen — you’d notice an improvement in normal pneumonia but not for Swine Flu or Covid-19 as these viruses would lead to alveolar capillary blockage (i.e. block ability of the lungs to operate in simple words). MB clears the blockage within 24 hours and O2 levels start improving. Covid-19 is a more virulent strain compared to H1N1 and a fast acting drug is necessitated.

Due to the clinico/pathological resemblance between H1N1 & Covid-19 — final outcome is expected to be similar post administration of MB.



(The above comparative X Rays are a part of a series. X Rays shared post consent from the patient)

Note : Some readers have questioned why it took 4 year to clear the lesions — given the state of the patient when he came to me, the chances of survival more than 6 months were less than 10% as his lung was severely damaged(X ray 1). In medical parlance, the above X Ray (X Ray 2) progress is considered a miracle.

(Will post more details about this as and when I get time — for queries please email me)

The detailed treatment regimen can be found by clicking here.


Comment below or mail me @ dr.deepak.golwalkar@gmail.com

View: https://dr-deepak-golwalkar.medium.com/treatment-for-covid-19-using-methylene-blue-d23fc5a31a4d
That's incredible, such amazing work. Thank you so much for sharing. I need to find a nebulizer then.

Does the article imply that O2 does not work on covid pneumonia patients at all?
 

md_a

Member
Thread starter
Joined
Aug 31, 2015
Messages
298
That's incredible, such amazing work. Thank you so much for sharing. I need to find a nebulizer then.

Does the article imply that O2 does not work on covid pneumonia patients at all?
BW: Now I remember you once telling me that at one point there was something called "firemen's oxygen" in which they had about 6 - 8 % carbon dioxide in the oxygen.
RP: Yeah, Yandell Henderson was the physiologist who got that popular to the point that fire departments all over the country started using it because the carbon dioxide at that very high concentration is extremely effective for restoring respiration to suffocated people, and for babies too that don't breathe properly.
BW: Is anyone still using carbon dioxide. Isn't it used or was used at some points in operation rooms?
RP: Oh, every now and then there is some person who says that hospitals are killing patients by giving them pure oxygen and say they would wish that hospitals switch, start using 5-8 % carbon dioxide whenever they give oxygen because it's basically stress inducing and toxic to give people oxygen in excess. At sea level we really have an excess of oxygen.
The Treatment of Pneumonia by Inhalation of Carbon Dioxide (Yandell Henderson)

"Nature has provided the lungs with several protective devices and reactions. The most obvious is the cough reflex by which irritating foreign bodies are removed. Less obvious, but more constantly acting, are the movements of respiration which are probably accompanied by peristaltic contractions and relaxations of the air tubes. The mucosa lining these tubes bears cilia which produce a continual flow of secretion from the depths of the lungs outward."

"Occlusion of an air tube puts all of these mechanisms for the clearing of the lungs out of action. The air in the occluded portion of the lung is soon absorbed, and the alveoli are deflated and collapsed. They are then gradually filled by accumulation of secretion. The conditions resulting are in all respects favorable to the development of microorganisms and, correspondingly, unfavorable both to the general defenses of the body and the special defenses of the lungs. It is a highly significant fact, as revealed by experiment, that in order to induce pneumonia in dogs it is not enough merely to introduce the pathogenic organisms into the lungs ; it is essential also to narcotize the animals so deeply that the cough reflex is abolished and respiration is depressed. In general, depressed or shallow breathing tends to permit the development of pneumonia, and deep breathing with full ventilation of the lungs tends strongly to inhibit it."

"In pneumonia it is the blocking of the lung airways, bronchi or bronchioli, by plugs of thick and sticky secretion which is the critical morbidic factor producing atelectasis [= collapse or closure of a lung resulting in reduced or absent gas exchange] and the conditions characteristic of an undrained infection." Inhalation of carbon dioxide results in opening up of pneumonic lungs."



158193817_1141212112974329_4360876660794958114_n.jpg
 

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  • Yandell Henderson -- The Treatment of Pneumonia by Inhalation of Carbon Dioxide.pdf
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