GorillaHead
Member
Androgen Receptor Accelerates Premature Senescence of Human Dermal Papilla Cells in Association with DNA Damage
The study claims that androgens damage dpc of non balding healthy people. It sats it accelerates senescence. So basically its rapid aging caused by androgens on the hair follicle.
before you guys say that androgens cause body hair growth thats actually not 100% true.
Men who have genetic aromatase deficiency have zero body hair. You need aromatase for hair to grow on the body seems.
Yet these men showed zero signs of hairloss on their scalps. So maybe serum estrogen causes body hair and scalp estrogen causes hair growth.
which invalidate the fact that aromatase is needed for body hair.
No one talks about the fact the skin has everything to do steroidgenesis and it works directly with hpa axis.
what if no aromatase in serum causes your skin to compensate by increasing aromatase hence aromatase deficient men have zero hair-loss cause they are only deficient in serum.
So in normal men who get older their aromatase increases which then causes the skin to down regulate aromatase in the skin tissue and up-regulate androgens to compensate. This results in less scalp hair and more body hair.
So genetically its all about your skin and how it responds to serum steroids?
The study claims that androgens damage dpc of non balding healthy people. It sats it accelerates senescence. So basically its rapid aging caused by androgens on the hair follicle.
before you guys say that androgens cause body hair growth thats actually not 100% true.
Men who have genetic aromatase deficiency have zero body hair. You need aromatase for hair to grow on the body seems.
Yet these men showed zero signs of hairloss on their scalps. So maybe serum estrogen causes body hair and scalp estrogen causes hair growth.
which invalidate the fact that aromatase is needed for body hair.
No one talks about the fact the skin has everything to do steroidgenesis and it works directly with hpa axis.
what if no aromatase in serum causes your skin to compensate by increasing aromatase hence aromatase deficient men have zero hair-loss cause they are only deficient in serum.
So in normal men who get older their aromatase increases which then causes the skin to down regulate aromatase in the skin tissue and up-regulate androgens to compensate. This results in less scalp hair and more body hair.
So genetically its all about your skin and how it responds to serum steroids?
Last edited: