Is There A Medication That Actually Antagonizes Estrogen?

[Opioidus]

I don't mean an aromatase inhibitor, they have severe short and long-term side effects and they merely occupy estrogen receptors, I'm looking for something that removes estrogen from the tissue.

 

[Dobbler]

Cheapish and supposedly effective combo is vitamin E + progesterone.

 

[lampofred]

Also thyroid, especially T3.

 

[Opioidus]

I'm looking for big pharma options since my issue is more serious.

I've tried all of that before to no avail.

 

[Frankdee20]

I'm looking for big pharma options since my issue is more serious.

I've tried all of that before to no avail.

Examastane doesn’t occupy receptors, it kills aroma tase enzymes until the body replaces them upon stopping the meds

 

[Opioidus]

Examastane doesn’t occupy receptors, it kills aroma tase enzymes until the body replaces them upon stopping the meds

Tried that and it was still ineffective. My issue is decreased urine flow and the only thing that helps is letrozole, no other AI or antiestrogen med or supp works. But letrozole is a hellish drug and I have to take at least 1.5 mgs every week to maintain the same flow.

 

[tankasnowgod]

I don't mean an aromatase inhibitor, they have severe short and long-term side effects and they merely occupy estrogen receptors, I'm looking for something that removes estrogen from the tissue.

Peat has said over and over that Progresterone both removes extrogen from the tissue and destroys the receptor proteins.

 

[Opioidus]

Peat has said over and over that Progresterone both removes extrogen from the tissue and destroys the receptor proteins.

I know but it doesn't deliver the desired results in me(increased urine flow). Although I've only used it topically.

 

[Frankdee20]

Tried that and it was still ineffective. My issue is decreased urine flow and the only thing that helps is letrozole, no other AI or antiestrogen med or supp works. But letrozole is a hellish drug and I have to take at least 1.5 mgs every week to maintain the same flow.

This doesn’t prove conclusively that Estrogen causes the issue though .... Low histamine and low acetylcholine can cause this, high aldosterone or high sodium can do that too

 

[Opioidus]

This doesn’t prove conclusively that Estrogen causes the issue though .... Low histamine and low acetylcholine can cause this, high aldosterone or high sodium can do that too

Why would letrozole ameliorate any of those issues?

 

[JKX]

What form of progesterone did you use? Have you tried progest E or progestene?

Pregnenolone and aspirin should also work.

 

[Opioidus]

What form of progesterone did you use? Have you tried progest E or progestene?

Pregnenolone and aspirin should also work.

I'm not sure, Pregnenolone noticeably worsens my symptoms, I haven't tried aspirin for some reason I'm scared of it lol.

 

[Fckingnameless]

Peat has said over and over that Progresterone both removes extrogen from the tissue and destroys the receptor proteins.

progesterone upregulates ER what you talking about??

 

[tankasnowgod]

progesterone upregulates ER what you talking about??

What's your source for this claim?

 

[Deleted member 5487]

Why not just a B complex the b1/2 Will clear out your estrogen at a natural and healthy pace, given the tools it needs.

 

[TheBeard]

they merely occupy estrogen receptors, I'm looking for something that removes estrogen from the tissue.

No, that's not how they work.

AI are the only pharma option that will do what you are after.
Or high dose DHT.