Antibiotic Resistance May Be Driven By Pesticides Like RoundUp (glyphosate)

Discussion in 'Scientific Studies' started by haidut, Oct 12, 2018.

  1. haidut

    haidut Member

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    I am sure most people on the forum have seen multiple news items on the topic of rapidly increasing antibiotic resistance of many bacterial strains causing the most common infections in both the general population and hospital patients. The official version is that this increasing resistance is due to doctors overprescribing antibiotics. However, the prescription data does not show an increase antibiotics treatments that could explain both the magnitude and the speed of resistance increase of the most common bacterial strains. One known environmental cause of increasing antibiotics resistance is the environmental pollution by SSRI drugs.
    SSRI Drugs Such As Prozac (fluoxetine) Cause Antibiotic Resistance

    The study below now shows that there is another ubiquitous environmental pollutant that may be contributing to the increasing resistance. The study found that the widely used pesticide RoundUp (gyphosate) by Monsanto, as well as the pesticide known as Kamba may be the driving force behind this rapidly increasing resistance. The study showed that bacteria exposed to both an antibiotic and one of the pesticides developed resistance up to 100,000 faster than when exposed to only the antibiotic. Since RoundUp is present in everything from tap water to commercially prepared/processed food, it is hard to imagine a case where a person prescribed antibiotics won't also be exposed to RoundUp for duration of the antibiotic treatment.

    Agrichemicals and antibiotics in combination increase antibiotic resistance evolution
    New study links common herbicides and antibiotic resistance

    "...A new study finds that bacteria develop antibiotic resistance up to 100,000 times faster when exposed to the world’s most widely used herbicides, Roundup (glyphosate) and Kamba (dicamba) and antibiotics compared to without the herbicide. This study adds to a growing body of evidence that herbicides used on a mass industrial scale, but not intended to be antibiotics, can have profound effects on bacteria, with potentially negative implications for medicine’s ability to treat infectious diseases caused by bacteria, says University of Canterbury scientist Professor Jack Heinemann, one of the study’s authors. “The combination of chemicals to which bacteria are exposed in the modern environment should be addressed alongside antibiotic use if we are to preserve antibiotics in the long-term,” he says. An important finding of the new study was that even in cases where the herbicides increase the toxicity of antibiotics they also significantly increased the rate of antibiotic resistance, which the study’s authors say could be contributing to the greater use of antibiotics in both agriculture and medicine."
     
  2. GAF

    GAF Member

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    I have long wondered if "antibiotic resistance" is real or is just another excuse to raise the prices of "new" drugs.

    Has "antibiotic resistance" actually been proven?
     
  3. Trix

    Trix Member

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    @haidut what are your thoughts on Stephanie Seneff's papers and slide shows. I have listened to her WAPF talks and there is so much that contributes to someone's health if exposed to glyphosate. If your aromatic amino acids become destroyed and the bacteria that is suppose to make your B vitamins are destroyed, the body gets dis-regulated and disease arrives out of nowhere. The doctors have no clue. Saturate the body with glycine and go organic? I have no idea how long it remains in our tissues. What I have read is they (M) stop the study at 3 months and that all the studies are safe, but after 3 months, this is when you see damage to the body. Maybe the reserves the body has, will make a difference as to how long you will notice something is not working correctly.
     
  4. OP
    haidut

    haidut Member

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    Well, if you expose a bacteria to non-lethal levels of antibiotic for hundreds of generations, eventually it will become more resistant to it but I don't think full resistance will develop. There are some strains like MRSA that are resistant from the get go, but those are mutated forms that for some reason thrive in hospitals but cannot survive in the wild like their less resistant cousins. There is a conspiracy theory that MRSA was developed as a bioweapon and got accidentally released and is now everywhere, including public transportation.
    KILLER BUG ON TRAINS AND BUSES
    Contamination of Public Buses with MRSA in Lisbon, Portugal: A Possible Transmission Route of Major MRSA Clones within the Community
     
  5. aguilaroja

    aguilaroja Member

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    Thank you. The Heinemann & Kurenbach group previously reported findings pointing toward similar concerns.
    This work continues to enlarge the picture about the context of antibiotic resistance. Factors are posing dangers to overall metabolism, and widespread overuse of antibiotics, including for animals, continues. SSRI's are another environmental chemical contributing to reduced antibiotic effectiveness, as mentioned here:
    SSRI Drugs Such As Prozac (fluoxetine) Cause Antibiotic Resistance

    Herbicide ingredients change Salmonella enterica sv. Typhimurium and Escherichia coli antibiotic responses
    "glyphosate, dicamba, and 2,4-D, as well as co-formulants in commercial herbicides, induced a change in susceptibility of the potentially pathogenic bacteria E. coli and S. enterica to multiple antibiotics."

    "The efficiency of plating (EOP) was determined for each defined concentration of antibiotic and active ingredient). The EOP is the ratio of the titre (c.f.u. ml−1) of a culture on treatment plates to the titre (c.f.u. ml−1) on LB[the medium]....In most cases the addition of active ingredient led to an increase in survival shown by higher EOP measurements at higher concentrations of antibiotic."

    "Antibiotic resistance is influenced by more factors than just exposure of bacteria to antibiotics. These other factors include manufactured products released into the environment....pure forms of dicamba, 2,4-D, and glyphosate, as well as common surfactants, can change the susceptibility of bacteria to a diverse range of antibiotics upon concurrent exposure. The inducing concentrations were well within the working concentrations of herbicides to which people, pets and farm animals may be exposed."

    "Toxicity data for these co-formulants are not usually required by regulators, and residues of co-formulants left by herbicides are not monitored."

    Sublethal Exposure to Commercial Formulations of the Herbicides Dicamba, 2,4-Dichlorophenoxyacetic Acid, and Glyphosate Cause Changes in Antibiotic Susceptibility in Escherichia coli and Salmonella enterica serovar Typhimurium
    "susceptibility of bacteria to antibiotics can be changed upon simultaneous exposure to herbicides."
    "...herbicide-induced antibiotic response was additive when chemicals that cause similar phenotypic changes were combined, e.g., Kamba and salicylic acid. This enlarges the range of potentially relevant human health or environmental exposures."

    "Killing curves in the presence and absence of sublethal herbicide concentrations showed that the directions and the magnitudes of responses varied by herbicide, antibiotic, and species. When induced, MICs of antibiotics of five different classes changed up to 6-fold. In some cases the MIC increased, and in others it decreased. Herbicide concentrations needed to invoke the maximal response were above current food maximum residue levels but within application levels for all herbicides. Compounds that could cause induction had additive effects in combination."
     
  6. Vinero

    Vinero Member

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    This is highly disturbing. These companies that produce this Glyphosphate might cause the dreaded post-antibiotic era, where people will die again from simple infections because antibiotics are ineffective. I seriously hope the government or medical world will realize how serious this is and step in and stop these companies from using this glyphospate.
     
  7. tankasnowgod

    tankasnowgod Member

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    Any time I hear "Antibiotic Resistance," I always think excess iron should be the first thing suspected. E.D. Weinberg stated at the beginning of his book "Exposing the hidden dangers of Iron" that a simple experiment done in the 1950's showed that iron could completely neutralize the effects of an antibiotic (he used tetracycline). None of the other elements or nutrients he tested at the time could do that.
     
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