TruffleGnocchi
Member
Hello everyone.
I wanted to ask via a reply to this post: If Estrogen Is So Bad, Why Does It Immediately Help but cannot because of new account restriction, so I'm making this, I hope it's in the right topic.
Why is it that a lot of older men just do Testosterone + AI or Testosterone only and that's all they need for their hypogonadal symptoms to resolve and life improvement in general. From reading this forum, I imagine adding at least pregnenolone and maybe DHT and low dose progesterone could make it better but for this example I will assume the men sharing their Testosterone only HRT success experiences are trustworthy and accurate enough.
So Testosterone injection only, brings increased muscle mass, increased strength, increased bone density, improved sex drive, erection quality, improved mental clarity, mental stability or control, motivation, resiliency, decreased anxiety, faster recovery from injury, improved blood sugar control, etc... Impressive for 1 molecule being added exogenously.
Why does HRT for females seem more complicated, much less consistently effective across multiple females, with a single strategy, such as progesterone only. If I remember correctly reading the women's experiences, some improve on progesterone only, some don't, some don't improve on progesterone + pregnenolone combination and only improve when estradiol is added. I wonder if for the women that only improve when E2 is added, is the E2 required only for vaginal dryness, pain and hotflashes? Or is it that E2 for those women is necessary to resolve other issues as well, like skin health, bone density, mental health.. Is it just the female reproductive organs that benefit from or require bigger amounts of E2, or is it that E2 in those cases, is replacing what Testosterone does for men, or women are somehow built different and require different signaling, or men get enough E2 from conversion from Testosterone and that is why Testosterone only HRT is all that is needed for some men?
1)If assuming E2 is required in greater amounts for women to function optimally, maybe adequate pregnenolone + DHEA would provide enough E2 for optimal function, without increasing risk of cancer and other things E2 is correlated with.
2)If assuming E2 does not play a beneficial role in men taking Testosterone only HRT, then that means it is likely the Testosterone itself that causes those effects or downstream mechanisms to provide all those benefits that Testosterone administration creates. If that were true, then maybe T could be the solution for those women that do not improve on Progesterone only protocol. Maybe something like a generous dose of progesterone, with pregnenolone + DHEA, and low/micro dose Testosterone would work for those females? Maybe all females would benefit? Without taking exogenous E2. There are some articles that state vaginal Testosterone reduce vaginal dryness. But the question would remain, why men still only need Testosterone and some women improve on Estradiol, no Testosterone involved.
3)If assuming E2 plays a beneficial role in men taking Testosterone only HRT, then maybe the same Prog + Preg + DHEA + low dose T would also work, and that could also be an explanation why Testosterone only HRT seems to work for some men. By aromatisation to Estrogen/s.
4) Any other possible explanations or theories for the experiences of those women?
Most men on youtube talking about their HRT practices never mention Progesterone at all. Maybe that could be an argument against the Progesterone only female HRT approach. While I personally doubt progesterone does not play some beneficial role, I cannot deny the testimonials of men on T only administration HRT strategy, feeling and performing great.
I think there must be some overlap between T only administration supposedly effective for a lot of men, and the desired female protocol that should be effective. There must be some overlap in the biology of both sexes, if not for vaginal dryness, at least for blood sugar control, sex drive, bone density, muscle mass, anti-obesity, mental benefits, etc..
If the E2 is a beneficial factor in the success of T only administration for male HRT or not, in either case maybe females could resolve their symptoms with just a generous dose Progesterone + low/micro dose Testosterone?
Any women tried testosterone and want to share the experience?
I wanted to ask via a reply to this post: If Estrogen Is So Bad, Why Does It Immediately Help but cannot because of new account restriction, so I'm making this, I hope it's in the right topic.
Why is it that a lot of older men just do Testosterone + AI or Testosterone only and that's all they need for their hypogonadal symptoms to resolve and life improvement in general. From reading this forum, I imagine adding at least pregnenolone and maybe DHT and low dose progesterone could make it better but for this example I will assume the men sharing their Testosterone only HRT success experiences are trustworthy and accurate enough.
So Testosterone injection only, brings increased muscle mass, increased strength, increased bone density, improved sex drive, erection quality, improved mental clarity, mental stability or control, motivation, resiliency, decreased anxiety, faster recovery from injury, improved blood sugar control, etc... Impressive for 1 molecule being added exogenously.
Why does HRT for females seem more complicated, much less consistently effective across multiple females, with a single strategy, such as progesterone only. If I remember correctly reading the women's experiences, some improve on progesterone only, some don't, some don't improve on progesterone + pregnenolone combination and only improve when estradiol is added. I wonder if for the women that only improve when E2 is added, is the E2 required only for vaginal dryness, pain and hotflashes? Or is it that E2 for those women is necessary to resolve other issues as well, like skin health, bone density, mental health.. Is it just the female reproductive organs that benefit from or require bigger amounts of E2, or is it that E2 in those cases, is replacing what Testosterone does for men, or women are somehow built different and require different signaling, or men get enough E2 from conversion from Testosterone and that is why Testosterone only HRT is all that is needed for some men?
1)If assuming E2 is required in greater amounts for women to function optimally, maybe adequate pregnenolone + DHEA would provide enough E2 for optimal function, without increasing risk of cancer and other things E2 is correlated with.
2)If assuming E2 does not play a beneficial role in men taking Testosterone only HRT, then that means it is likely the Testosterone itself that causes those effects or downstream mechanisms to provide all those benefits that Testosterone administration creates. If that were true, then maybe T could be the solution for those women that do not improve on Progesterone only protocol. Maybe something like a generous dose of progesterone, with pregnenolone + DHEA, and low/micro dose Testosterone would work for those females? Maybe all females would benefit? Without taking exogenous E2. There are some articles that state vaginal Testosterone reduce vaginal dryness. But the question would remain, why men still only need Testosterone and some women improve on Estradiol, no Testosterone involved.
3)If assuming E2 plays a beneficial role in men taking Testosterone only HRT, then maybe the same Prog + Preg + DHEA + low dose T would also work, and that could also be an explanation why Testosterone only HRT seems to work for some men. By aromatisation to Estrogen/s.
4) Any other possible explanations or theories for the experiences of those women?
Most men on youtube talking about their HRT practices never mention Progesterone at all. Maybe that could be an argument against the Progesterone only female HRT approach. While I personally doubt progesterone does not play some beneficial role, I cannot deny the testimonials of men on T only administration HRT strategy, feeling and performing great.
I think there must be some overlap between T only administration supposedly effective for a lot of men, and the desired female protocol that should be effective. There must be some overlap in the biology of both sexes, if not for vaginal dryness, at least for blood sugar control, sex drive, bone density, muscle mass, anti-obesity, mental benefits, etc..
If the E2 is a beneficial factor in the success of T only administration for male HRT or not, in either case maybe females could resolve their symptoms with just a generous dose Progesterone + low/micro dose Testosterone?
Any women tried testosterone and want to share the experience?