hypogonadism

  1. S

    Kiwi modulates my secondary narcolepsy and hypogonadism symptoms

    All my life I have struggled with sleep attacks during the day. Going Peaty helped me avoid these attacks during the day (making me employable), but in the afternoon and evening they occur at least once. They occur enough that I really can't get involved with things outside of family...
  2. haidut

    Oral pregnenolone as hormone replacement therapy (HRT) in humans

    As many of my readers know, the first step in steroid synthesis is the so-called "side-chain cleavage", which converts cholesterol into pregnenolone (P5). That step is known as the rate-limiting step in the steroid cascade, and its function depends on the redox status and ATP levels. In other...
  3. haidut

    Low energy production (glucose metabolism) may cause andropause

    As many of my readers know, aging men can also experience the equivalent of menopause and doctors informally call that state "andropause". Its official name is age-related hypogonadism and most of that hypogonadism is of the "secondary" type - i.e. the gonads appears to be in fine shape but for...
  4. haidut

    Endotoxin Has A G.E.L.D.I.N.G Effect, Causes Obesity And Hypogonadism

    A very interesting study proposing that the decline in gonadal function seen in obese/diabetic men is due to chronically elevated endotoxin levels in such people. The study calls this phenomenon (G)ut (E)dotoxin (L)eading to a (D)ecline (I)n (G)onadal function (GELDING) due to the remarkable...
  5. haidut

    Endocrine Disruptors In Sunscreen Absorb Systemically And Persist For Days

    So much for the safety of sunscreen. Of course, the article immediately goes on the defensive and warns against stopping sunscreen. It even includes gems like "The sun is the real enemy here" and keeps repeating the mantra that it is all about risk-benefits analysis. Yet, even MSM is forced to...
  6. haidut

    CNN News - Running Lowers Testosterone In Males

    When news like this features on CNN, it is becoming obvious that something it not right with the official recommendations for regular (endurance) exercise as the best way to ward off CVD, cancer, brain diseases, osteoporosis, etc. The CNN piece also states that vitamin D supplements, weight...
  7. haidut

    PUFA Inhibit Progesterone Production And Thus Drive/cause Menopause

    Peat wrote in a few of his articles that menopause is largely driven by a deficiency of progesterone and mentioned several anecdotes of women in their 50s and 60s getting their periods back after supplementing with large doses progesterone. In one of his articles he said that PUFA and estrogen...
  8. haidut

    "Normal" TSH Above 2 As A Cause Of Unexplained Infertility

    As most of the people on this forum know, Peat has spoken many times about the optimal values of TSH and has said that its value should be as close to 0 as possible. I posted a study some time ago showing that "normal" TSH levels above 2 are associated with a number of health issues that baffle...
  9. haidut

    Raising Serum Androgens Using DHEA, Pregnenolone, And Vitamin K

    User testimony (4/26/2021): My Experiences With Raising Androgens Log (Pansterone, k2, magnoil) Many people use supplements like DHEA, pregnenolone, and progesterone with the goal of raising their androgens and lowering estrogen. While this approach works for raising tissue levels of steroids...
  10. P

    Premature Ejaculation

    Clomiphene Effects on Idiopathic Premature Ejaculation - Nephro-Urology Monthly - - Kowsar Background: Premature ejaculation (PE) is the inability to delay ejaculation, occurring sooner than they or their partner would like during sexual activities. PE is a challenging problem that can affect...
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