• Due to excessive bot signups along with nefarious actors we are limiting forum registration. Keep checking back for the register link to appear. Please do not send emails or have someone post to the forum asking for a signup link. Until the current climate changes we do not see a change of this policy. To join the forum you must have a compelling reason. Letting us know what skills/knowledge you will bring to the community along with the intent of your stay here will help in getting you approved.

anti-aging

  1. PeskyPeater

    Wheat bran- but not oat bran-enriched diets increase the mucosal height of the cecum and colon of newly weaned and aged rats

    "In spite of the reports mentioned above, it is not known whether the effect of a water-soluble fiber-enriched diet (the main source of SCFA) on the mucosa of the large bowel is more pronounced than that of an insoluble fiber-enriched diet. In the present study, we determined the effect of...
  2. Sefton10

    Vitamin D supplementation is associated with slower epigenetic aging

    Adverse effects of low vitamin D level on mortality and morbidity are controversially discussed. Especially older people are at risk for vitamin D deficiency and therefore exposed to its potentially harmful consequences. A way of measuring differences in the biological age is through DNA...
    • Sefton10
    • Thread
    • aging anti-aging epigenetic vitamin d
    • Replies: 13
    • Forum: Vitamins
  3. A

    Hypercapnia-inducible factor: a hypothesis | Aging and longevity

    Abstract Cells and tissues sense and respond to hypercapnia by global activation or down-regulation of hundreds of genes and switching on/off a number of signaling and metabolic pathways. We hypothesize for the first time that such complex rearrangements are hardly possible without subtle...
  4. youngsinatra

    Rate My Anti-Aging Stack

    Hello everyone, I am personally very interested in longevity and extending healthy lifespan. I am curious if some of you are also into this field of interest and could give me some advice for what you would change/add/remove. My supplement stack: 1. Fat-solubles: (All dissolved in MCT-oil...
  5. P

    55 year-old looks like 25

    Interesting video about a 55 year-old photographer who looks like an elite 25 year-old fitness model. He's 55 Years Old But Looks 25... Reacting To Chuando Tan Reveal His Secrets Summary: He looks the same as he did in the late 1980s, in his 20s. He doesn't drink or smoke, doesn't drink coffee...
  6. haidut

    Policosanol Is Antiviral And A Potent Inducer Of Anti-aging Gene Klotho

    This post is a good complement to the recent ones I did on androgens, estrogens and their opposing effects on the expression of the anti-aging gene Klotho. While I was doing research on that gene, I had a "random" thought pop up in my mind. It is well-known that some Caribbean countries have a...
    • haidut
    • Thread
    • aging anti-aging covid-19 klotho octacosanol policosanol sars-cov-2 sfa
    • Replies: 47
    • Forum: Scientific Studies
  7. haidut

    Androgens Boost, Estrogen Inhibits, Anti-aging Gene Klotho

    This post has two main messages, based on the studies below. Namely, androgens (and especially DHT) potently increase the expression of the anti-aging gene Klotho while estrogens strikingly decrease its expression. Moreover, the more potent the androgen, in terms of androgen receptor (AR)...
    • haidut
    • Thread
    • aging androgen anti-aging dht espression estrogen gene klotho
    • Replies: 1
    • Forum: Scientific Studies
  8. haidut

    Topical DHEA Has Potent Anti-aging Effects On Human Skin

    I often get emails in regards to possible interventions with anti-aging effects on skin. The study I usually quote is an old one (circa 1967) that did extensive tests on 200+ people with age range of 57-88 years residing in a retirement home, and demonstrated that topical testosterone (1%) cream...
    • haidut
    • Thread
    • androgen anti-aging dhea dht pregnenolone progesterone rejuvenate skin
    • Replies: 21
    • Forum: Scientific Studies
  9. haidut

    Simply Diluting "old Blood" Has The Same Anti-aging Effects As Parabiosis

    The topic of using blood from young people to stave off aging and disease is hardly new. Rumors have been circulating for centuries that the old and rich use all kinds of gruesome methods to acquire blood from young people and use that blood for all sorts of bizarre rejuvenating procedures...
    • haidut
    • Thread
    • anti-aging blood debris dilultion ffa health mechanism parabiosis
    • Replies: 43
    • Forum: Scientific Studies
  10. L

    Deprenyl – Peatarian-Safe?

    Has anyone asked Ray Peat his opinion about this drug? Would he think it is safe for long term usage? Do you think it is safe, and good to use as a nootropic?
    • Logan-
    • Thread
    • anti-aging brain deprenyl dopamine dopaminergic longevity mao-b nootropic selegiline
    • Replies: 21
    • Forum: Pharmaceutical Drugs
  11. haidut

    6-keto P4 - Liquid 6-ketoprogesterone For Lab/R&D

    As many forum users know, preventing tissue destruction as a result of hypothyroidism and stress is one of the main topics the pro-metabolic approach focuses on. While tissue catabolism can be drive by a number of mediators working in tandem, the main catabolic steriod in the human organism is...
    • haidut
    • Thread
    • 6-keto p4 6-keto progesterone 6-keto-progesterone 6-ketoprogesterone anti-aging anti-cortisol anticatabolic glucocorticoid glucocorticoid antagonist glucocorticoid receptor gr hypertrophic muscle pregn-4-ene-3;6;20-trione
    • Replies: 402
    • Forum: IdeaLabs
  12. H

    Best Anti-Wrinkle Supplements For Men?

    MSM, K2 MK-4, Progesterone, Vitamin A...Anything else?
    • hotte
    • Thread
    • anti-aging skills wrinkles
    • Replies: 31
    • Forum: Supplements
  13. haidut

    Calcirol - Liquid Vitamin D3

    Just like the other vitamin products we have released, this product does not really need any introduction to anybody familiar with Peat's work. So, unlike other products of ours, there won't be as many references listed in support of this product but I think even the few ones below are enough to...
    • haidut
    • Thread
    • anabolic androgens anti-aging anti-estrogen anticortisol calcirol calcium cholecalciferol klotho secosteroid vitamin d vitamin d3
    • Replies: 355
    • Forum: IdeaLabs
  14. haidut

    CortiNon - Liquid Progesterone/DHEA Mix

    This product does not really need any introduction to anybody familiar with Peat's work. I have wanted to release it for a long time but over the last few months the studies I found related to the anabolic and anticatabolic effects of progesterone, combined with the fact that Peat has told quite...
    • haidut
    • Thread
    • anabolic androgenic anti-adrenaline anti-aging anti-anxiety anti-catabolic anti-cortisol anti-endotoxin anti-inflammatory cortinon dhea progesterone
    • Replies: 354
    • Forum: IdeaLabs
  15. P

    Action Of Topical Thyroid Hormone Analogue In Reversing Glucocorticoid-induced Skin Atrophy

    Action of topical thyroid hormone analogue, triiodothyroacetic acid in reversing glucocorticoid-induced skin atrophy in humans. - PubMed - NCBI Abstract The present study concerns the effect of topical treatment with a cream formulation of triiodothyroacetic acid (TRIAC) in comparison with a...
  16. P

    Vitamin B3 Modulates Mitochondrial Vulnerability And Prevents Glaucoma In Aged Mice

    Vitamin B3 modulates mitochondrial vulnerability and prevents glaucoma in aged mice. - PubMed - NCBI Glaucomas are neurodegenerative diseases that cause vision loss, especially in the elderly. The mechanisms initiating glaucoma and driving neuronal vulnerability during normal aging are...
  17. Dan W

    Methylene Blue For Skin Health

    A new study (h/t Mike Lustgarten) on methylene blue for skin health: Anti-Aging Potentials of Methylene Blue for Human Skin Longevity
    • Dan W
    • Thread
    • aging anti-aging antioxidant methylene blue ros skin study
    • Replies: 3
    • Forum: Methylene Blue
  18. Dessert_All_Day

    Google Is Super Secretive About Its Anti-aging Research. No One Knows Why

    Google is super secretive about its anti-aging research. No one knows why. Thoughts? Speculation?
Top