anti-aging

This post is a good complement to the recent ones I did on androgens, estrogens and their opposing effects on the expression of the anti-aging gene Klotho. While I was doing research on that gene, I had a "random" thought pop up in my mind. It is well-known that some Caribbean countries have a...

This post has two main messages, based on the studies below. Namely, androgens (and especially DHT) potently increase the expression of the anti-aging gene Klotho while estrogens strikingly decrease its expression. Moreover, the more potent the androgen, in terms of androgen receptor (AR)...

I often get emails in regards to possible interventions with anti-aging effects on skin. The study I usually quote is an old one (circa 1967) that did extensive tests on 200+ people with age range of 57-88 years residing in a retirement home, and demonstrated that topical testosterone (1%) cream...

The topic of using blood from young people to stave off aging and disease is hardly new. Rumors have been circulating for centuries that the old and rich use all kinds of gruesome methods to acquire blood from young people and use that blood for all sorts of bizarre rejuvenating procedures...

As many forum users know, preventing tissue destruction as a result of hypothyroidism and stress is one of the main topics the pro-metabolic approach focuses on. While tissue catabolism can be drive by a number of mediators working in tandem, the main catabolic steriod in the human organism is...

MSM, K2 MK-4, Progesterone, Vitamin A...Anything else?

Just like the other vitamin products we have released, this product does not really need any introduction to anybody familiar with Peat's work. So, unlike other products of ours, there won't be as many references listed in support of this product but I think even the few ones below are enough to...

This product does not really need any introduction to anybody familiar with Peat's work. I have wanted to release it for a long time but over the last few months the studies I found related to the anabolic and anticatabolic effects of progesterone, combined with the fact that Peat has told quite...

Action of topical thyroid hormone analogue, triiodothyroacetic acid in reversing glucocorticoid-induced skin atrophy in humans. - PubMed - NCBI Abstract The present study concerns the effect of topical treatment with a cream formulation of triiodothyroacetic acid (TRIAC) in comparison with a...

Vitamin B3 modulates mitochondrial vulnerability and prevents glaucoma in aged mice. - PubMed - NCBI Glaucomas are neurodegenerative diseases that cause vision loss, especially in the elderly. The mechanisms initiating glaucoma and driving neuronal vulnerability during normal aging are...

A new study (h/t Mike Lustgarten) on methylene blue for skin health: Anti-Aging Potentials of Methylene Blue for Human Skin Longevity

Google is super secretive about its anti-aging research. No one knows why. Thoughts? Speculation?