What's the relationship between adrenaline, thyroid and estrogen? Do estrogen surges create thyroid drops, then adrenaline kicks in to create energy? Here's why I'm asking. I'm menopausing hard -- insane adrenaline surges with hot flashes, and a constant low-grade hyper-adrenaline state. I'm eating tons (including sugar), but that's not really helping. And weirdly, my thyroid is lower now than it's ever been, which makes me think that's a factor, too. But I don't know how to conceptualize what's happening -- I just know I have high adrenaline, low thyroid, and my estrogen is doing what estrogen does at menopause that whacks people out. BTW, I was taking bioidentical estrogen along with progesterone until 10 weeks ago, but about a month after I stopped the estrogen and just stuck with progesterone, the hot flashes/adrenaline surges started.