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Sounds similar to me then in some ways, we'll keep in touch and first one to start to see some weight loss can holler and instill some hope in the other.
Agreed!Well it will be interesting
Sounds similar to me then in some ways, we'll keep in touch and first one to start to see some weight loss can holler and instill some hope in the other.
Well at first it was a one-liner, but... I thought it made me come off as a **** so hence the added fluff. :p
Yeah I've heard about the questionable uptake of it so who knows what the actual dose was that I absorbed? But I did feel it though. I was going to try and order some Progest-E but held off since I started to notice the weight gain quite early, and my wife was not very interested to try some herself. At the moment I can't say I feel very inclined to try any form of progesterone again, but maybe some day down the road when the dust has settled. I hear you though and appreciate the advice. :)
Yeah the intestines and liver needs to be addressed for sure and they could at least in part be responsible for the weight gain. But I agree that I think they are the main suspects when it comes to the migraines, depressive tendencies and low energy. I continue to explore ways to make it better. I think the hormones, perhaps even the thyroid in my case, are but band aids at best. I've tried the others but not biotin except for as part of a B-complex so quite low dose I guess.
Yes I must admit I have gained a new level of awe and respect for my body and God's/nature's amazing wisdom and balance. Wish I could say I'd gained a bigger hunger but that is a "problem" of many years, that I don't really get hungry much, but that's back to my problems with the stomach (acid - lack of?) and liver I think. But I hear you and... Well it's never too late to say we were "wrong", been there many times myself of course.
Well in my case I started to have outbreaks on my chest during the autumn, acne and eczema. I've sort of always had a little acne every now and then but now it's just more. I've eaten my fair share of liver during this time, as well as milk products, but the vitamin D3 I actually put away earlier this winter. Eaten it more or less during the no sun on my skin-phase of the year for many years. I remember when it started to get pushed in the "alternative media" many years ago, and now it's just mainstream. So I don't know... Which is probably the wisest thing I can say, once again. Appreciate all you good people's input though, I'm sure some seeds have been planted in me, so... Time will tell. Uhm, I will just try to stop writing now!
with what you have written, I suspect you may have SLEEP APNEA, which causes so many problems, hypthyroidism, even when treated with hormones, is linked to sleep apnea. Progesterone at very high doses causes Insulin resistance, you are on a regular dose, but as we age insulin resistance is almost inevitable when our hormones dwindle. high as well as low testosterone increase risk for sleep apnea. Furthermore, Progesterone helps with respiration due to the metabolite allopregnanolone. HOWEVER,,,,Progesterone also causes muscle LAXITY, meaning it makes you "looser", think about pregnancy and females making tons of Progesterone especially last month before birth, where it aids her body to widen and be looser to allow baby out of birth canal.Hello there all you good people on this forum! :)
I've been lurking for perhaps two years or more and finally managed to sign up this winter, and this will be my first post. It's been long in the making but finally I caved in since I don't really know what to do about my situation.
In short I'm a man in my mid 40’s from Sweden. For those with better memory than me who listens to Ray Peat interviews with Patrick Timpone, I’ve sent in a question or two over the years. Then like now my main concern has been my ever increasing migraines.
I’ve been on thyroid for over two years in various doses but besides bringing my temps up and getting the warmth back in my extremities, no small feat I guess, it hasn’t really done anything else. I’ve always been skinny and could eat anything without my weight even blinking. I added some DHEA and pregnenolone and it also didn’t do much, although the DHEA helped my libido that had been tanking after 40 or so, but at least my weight and migraines were the same. This was early last year.
Enter this summer and me getting my hands on some Progesterone cream (Source Naturals). Finally I felt I’d found something that helped at least a little with my migraines - less and not as strong and I was thrilled! In the end of August I took a course of penicillin after a summer cold that never seemed to want to give up (I supposedly had “Covid” in December of 2020 and life somehow hasn’t been the same, at least my immune system), and this really wrecked my stomach which hasn’t really recovered fully yet despite all the probiotics, home made kefir or whatever I’ve thrown at it, as well as strong essential oils like oregano on the other side to try to kill of something nasty. Before this I had also started to sleep quite bad and for this reason started low dose Mirtazapine which will knock out most people with it’s antihistamine effect. I had to stop it though in November since I got some strange joint pains which I’ve never felt before (yes it wasn’t the first time with Mirtazapine).
And at least somewhere there in November at least I had to realize that I was really starting to be quite fat, especially around my belly (but it’s really all over). From always weighing under 70 kg (about 155 lbs) for 20+ years, and wanting to gain weight, I was now like 80+ kg (175 lbs). This would be more normal for a guy about 1.80m tall (5’11”) but since I’m anything but muscular still and it’s all just fat, it’s not funny and has gotten quite unpractical. I never though a big belly could get in the way so much…! And I don’t think it’s water since I don’t see any signs of edema in my feet and ankles (been there at times) and the fat has sort of a cellulite tendency.
So I didn’t know what was the culprit but being afraid to stop the progesterone I continued. After the holidays I had gained a few more kilos and sometime in January I stopped the pregnenolone. 3-4 weeks ago I finally had to try and cut the progesterone, then two weeks after or so I also stopped the DHEA. I have slowly gained another kilo or so after this and am now around 86 kg (190 lbs).
So during all this time I was taking about:
5-10mg progesterone in the evening as a cream, applied to the back of my neck always since that’s where my migraine sort of starts.
10-25mg of pregnenolone orally in the evening.
5-12,5mg of DHEA orally in the morning.
I know this has already gotten way too long, but what the heck should I do at this point? I think it must be the progesterone since everything else has never touched my weight before, including the very few antibiotics I have taken through the years. Could it be enough to just stop all and hope things might balance out with time, or should I perhaps try the approach that at least some women do and take a much higher dose of progesterone (and I would then like to finally try to get me some Progest-E) for a while? As for libido and so on I can’t say it really has become worse during my time with progesterone, maybe even a little better.
If anyone has made it this far I would surely appreciate any input you might have or gladly answer any questions. Sorry to be “another train wreck” on here but if nothing else maybe it could be a cautionary tale or something. It all just became a sort of perfect storm where I didn’t know what was doing what. If I’d been more energetic and alive I would have stopped earlier I guess but there is quite a bit of anhedonia and barely making it through the day energetically, so… Just turning myself into another lab rat I guess.
Sorry for the late response, but yes. I don't always measure it out perfectly, but I shoot for something that would be much closer to this than the lower limit described in the previously mentioned article. It may not be an ideal dose for many, but my experiences have led me to err on the side of possibly too much rather than not enough as when I get migraines they can last several days.
This has been my experience, ive always been effortlessly ripped and skinny, could never gain fat whatsoever even when eating mass amounts of pufa in the past, ive always had a 6 pack, and i still do, but ever since trying progesterone in the past i just gain all this aboyying persistant fat around my lower abdomen, i can still see my 6 pack, but whenever i bend over i got these like inflated rolls its strange, no matter how much exercise i do, what i eat it still persists and its been maybe 2 or 3 years since i touched progesterone, im not sure what happened but i think i seriously messed something up, i think progesterones anti androgenic effects have something to do with it and i think it does something long term to adrogens that we need to figure out how to reverse, im probably never gonna touch that stuff again, and its just iritating because its this extremely persistant belly fat only that just wont **** off, i cant say forsure it was progesterone but all i know was i was absolutely shredded all my life before taking it and ever since taking it now ive been fluffy ever since, like i said i can still see my 6 pack but theres this anoyying layer of fluff that just wont **** off, i went up to 190 pounds at my max, down to 175 now but still with this anoyying layer of abdomen fat that i need to find out some way to send it to the underworld,Hello there all you good people on this forum! :)
I've been lurking for perhaps two years or more and finally managed to sign up this winter, and this will be my first post. It's been long in the making but finally I caved in since I don't really know what to do about my situation.
In short I'm a man in my mid 40’s from Sweden. For those with better memory than me who listens to Ray Peat interviews with Patrick Timpone, I’ve sent in a question or two over the years. Then like now my main concern has been my ever increasing migraines.
I’ve been on thyroid for over two years in various doses but besides bringing my temps up and getting the warmth back in my extremities, no small feat I guess, it hasn’t really done anything else. I’ve always been skinny and could eat anything without my weight even blinking. I added some DHEA and pregnenolone and it also didn’t do much, although the DHEA helped my libido that had been tanking after 40 or so, but at least my weight and migraines were the same. This was early last year.
Enter this summer and me getting my hands on some Progesterone cream (Source Naturals). Finally I felt I’d found something that helped at least a little with my migraines - less and not as strong and I was thrilled! In the end of August I took a course of penicillin after a summer cold that never seemed to want to give up (I supposedly had “Covid” in December of 2020 and life somehow hasn’t been the same, at least my immune system), and this really wrecked my stomach which hasn’t really recovered fully yet despite all the probiotics, home made kefir or whatever I’ve thrown at it, as well as strong essential oils like oregano on the other side to try to kill of something nasty. Before this I had also started to sleep quite bad and for this reason started low dose Mirtazapine which will knock out most people with it’s antihistamine effect. I had to stop it though in November since I got some strange joint pains which I’ve never felt before (yes it wasn’t the first time with Mirtazapine).
And at least somewhere there in November at least I had to realize that I was really starting to be quite fat, especially around my belly (but it’s really all over). From always weighing under 70 kg (about 155 lbs) for 20+ years, and wanting to gain weight, I was now like 80+ kg (175 lbs). This would be more normal for a guy about 1.80m tall (5’11”) but since I’m anything but muscular still and it’s all just fat, it’s not funny and has gotten quite unpractical. I never though a big belly could get in the way so much…! And I don’t think it’s water since I don’t see any signs of edema in my feet and ankles (been there at times) and the fat has sort of a cellulite tendency.
So I didn’t know what was the culprit but being afraid to stop the progesterone I continued. After the holidays I had gained a few more kilos and sometime in January I stopped the pregnenolone. 3-4 weeks ago I finally had to try and cut the progesterone, then two weeks after or so I also stopped the DHEA. I have slowly gained another kilo or so after this and am now around 86 kg (190 lbs).
So during all this time I was taking about:
5-10mg progesterone in the evening as a cream, applied to the back of my neck always since that’s where my migraine sort of starts.
10-25mg of pregnenolone orally in the evening.
5-12,5mg of DHEA orally in the morning.
I know this has already gotten way too long, but what the heck should I do at this point? I think it must be the progesterone since everything else has never touched my weight before, including the very few antibiotics I have taken through the years. Could it be enough to just stop all and hope things might balance out with time, or should I perhaps try the approach that at least some women do and take a much higher dose of progesterone (and I would then like to finally try to get me some Progest-E) for a while? As for libido and so on I can’t say it really has become worse during my time with progesterone, maybe even a little better.
If anyone has made it this far I would surely appreciate any input you might have or gladly answer any questions. Sorry to be “another train wreck” on here but if nothing else maybe it could be a cautionary tale or something. It all just became a sort of perfect storm where I didn’t know what was doing what. If I’d been more energetic and alive I would have stopped earlier I guess but there is quite a bit of anhedonia and barely making it through the day energetically, so… Just turning myself into another lab rat I guess.
