NO Erection VS CO2 Erection

[Coderr]

Drinking sparkling water will help erection?

 

[Aries]

There is ample evidence of erectile pathways that have nothing to do with NO.

Do you have studies?

Also on the notion of nitric oxide causing excessive libido and premature ejaculation. PDE5 inhibitors certainly don't which takes a lot away from that theory.

 

[Kunstruct]

PDE5 inhibitors certainly don't which takes a lot away from that theory.

Actually some guys take it just to delay ejaculation, just ask someone who takes it and they'll tell you.

 

[Kunstruct]

Drinking sparkling water will help erection?

What is stopping someone from drinking sparkling water to find out?

 

[ecstatichamster]

Do you have studies?

Also on the notion of nitric oxide causing excessive libido and premature ejaculation. PDE5 inhibitors certainly don't which takes a lot away from that theory.

Androgenic maintenance of the rat erectile response via a non-nitric-oxide-dependent pathway. - PubMed - NCBI
Abstract
Prior studies have demonstrated that the erectile response in the rat penis is androgen dependent and is mediated by nitric oxide (NO), the neurotransmitter synthesized by the enzyme nitric oxide synthase (NOS). The present studies used L-nitro-L-arginine methyl ester (L-NAME), an inhibitor of NOS, to determine if androgens also regulate alternative pathways leading to the erectile response but not mediated by NO. Castrated rats that were treated with L-NAME (L-NAME CASTRATE) exhibited little or no increase in intracavernosal pressure in response to stimulation of the major pelvic ganglion. This ganglion controls blood flow into the penis and, when stimulated, normally leads to erection. However, when castrated animals were treated with testosterone along with L-NAME (L-NAME TESTO), the animals responded to the ganglionic stimulation with increased intracavernosal pressure. This finding suggests that there are other androgen-dependent pathways that lead to penile erection but are not mediated by NO. Erection occurred in both L-NAME CASTRATE and L-NAME TESTO rats in response to intracavernosal injection of sodium nitroprusside (an NO donor drug), proving that the NO responsive mechanisms were unaffected by the inhibition of NOS activity. To investigate further the nature of this NO independent pathway, L-NAME CASTRATE and L-NAME TESTO rats were treated with either zaprinast (a specific phosphodiesterase 5 inhibitor), which would block the breakdown of cGMP to 5'GMP, or methylene blue (an inhibitor of guanylate cyclase) to prevent the synthesis of cGMP. Zaprinast treatment led to increased erectile response in L-NAME TESTO rats but not in L-NAME CASTRATE rats, demonstrating that androgen-sensitive alternative pathways increased guanylate cyclase activity. Methylene blue inhibited the erectile response in all treatment groups, showing that cyclic GMP is critical to the NO-independent pathway as well as the NO-dependent pathway. Taken together, these results support the hypothesis that androgens maintain the erectile response by alternate pathways, including one that is independent of NO but involves the synthesis of cyclic GMP.

 

[vulture]

Do you have studies?

Also on the notion of nitric oxide causing excessive libido and premature ejaculation. PDE5 inhibitors certainly don't which takes a lot away from that theory.

I second that. I have had lots of athletic sex sessions on Viagra, no premature ejaculation on most of them, maybe even in all of them

 

[Scenes]

Reviving this thread to say I still get ED issues whenever I use methylene blue (oxidal) or use redlight. They both lower nitric oxide. Does my body rely far too much on NO to perform?

Would love to know how to get this magical co2 erection the gurus speak of.

Things that help a bit include pregnenolone, b1, sunlight.

Things that help a lot are magnesium and stopping redlight and MB.

Any thoughts?

 

[TheCalciumCad]

High metabolism, Androgens and Low estrogens Erections!

Also Dopamine (sunlight in the retina/tyrosine/T3) and avoid porn

 

[redsun]

Reviving this thread to say I still get ED issues whenever I use methylene blue (oxidal) or use redlight. They both lower nitric oxide. Does my body rely far too much on NO to perform?

Would love to know how to get this magical co2 erection the gurus speak of.

Things that help a bit include pregnenolone, b1, sunlight.

Things that help a lot are magnesium and stopping redlight and MB.

Any thoughts?

Magical CO2 erection? There is no such thing.

 

[lvysaur]

Things I've noticed about "CO2" erection (which coincides with a flat occiput for me)

- longer to come online (or more foreplay, is another way of looking at it)
- lasts longer
- much less compulsion to orgasm
- less compulsion to watch porn
- change in sexual preference (attracted to more "modest" sexual features, less desire to be "rough", rather "gentle")
- not fixated on certain body parts (butt or breasts for example)
- in the instant before orgasm, no compulsion to flex the pubococcygeal muscle (normally I flex the PC muscle before orgasm).
- no exhaustion, fatigue, or anhedonia after orgasm
- sometimes have spontaneous "dry mini orgasms" (simply thinking about sex results in small orgasm, without ejaculate, within a few minutes. No orgasm-associated exhaustion or fatigue here either.)

Other non-sexual things that coincide with this mode:

- hunger is similar in quality to sex drive (deeper, more consistent, yet can be ignored easily)
- flat occiput, already mentioned
- torso is wider/fuller in the left-to-right direction
- face is fuller
- mental and physical activity (chores, errands, surfing internet, typing) is very deliberate
- no compulsion to play video games, check social media

Just to be clear, I put "CO2" in quotes because I have no idea what is going on wrt CO2. All I know is that this is a desirable mode to be in, so I am betting that it's associated with CO2 as opposed to Nitric Oxide.

I mentioned this last year but I'll link it here: Libido. A Good Or Bad Sympton
From @Glassy

The desire for sex is there every second day (by the 3rd day is quite strong) and I’m starting to enjoy the feeling of walking around with a loaded weapon. The need for relief has largely gone and has been replaced with a sense of ‘I’m locked and loaded’. It’s taken me a while to appreciate this change as initially I thought it was a drop in libido.

People always rave about No-Fap, and in my opinion this is why. I don't think that No-Fap does anything. Rather, being in a healthy state makes one able to maintain No-Fap--many subsequently end up thinking that No-Fap was responsible for the benefits (reverse causation).

 

[frankmp0]

I’ve taken methylene blue in 10mg quantities and it doesn’t hurt erections at all. I’ve mistakenly put a bunch of MB on my penis and it didn’t hurt my erections at all.

There is ample evidence of erectile pathways that have nothing to do with NO.

I laughed out loud from this, thank you. Can you bless me with this story?

 

[ecstatichamster]

I laughed out loud from this, thank you. Can you bless me with this story?

not sure I understand. Just what I stated.

 

[olowshinenine]

I find my erections are much better after using co2 (bagging legs and torso). Red light sometimes weakens my erections if I overexpose nuts but I’ve begun limiting exposure to gonads and finding erections are.....A1.

I thought red and infrared light was good for gonads and boosting testosterones. ??

 

[olowshinenine]

There are a lot of concepts on this forum that are new to me especially this talk of CO2 can someone please point me to a beginner guide about the basic principles? I have problems with my libido and erections and I would like to know more. I have been chasing NO for several years now thinking this is the best thing for blood pressure and erections.

 

[frankmp0]

not sure I understand. Just what I stated.

How you got methylene blue on your penis

 

[ecstatichamster]

How you got methylene blue on your penis

I was using it (diluted well) to treat balanitis. It actually worked.