Natural Progesterone (but Not Synthetic Progestins) Has Potent Anti-hypertensive Effects

haidut

Member
Joined
Mar 18, 2013
Messages
17,613
Location
USA / Europe
As many readers already know, synthetic estrogens and progestins currently dominate the market for female reproductive health. These chemicals are in everything from birth control pills, to drugs for "treating" endometriosis, to drugs for menopausal symptoms, to treating neurodegenerative diseases such as Alzheimer's, etc. The argument for using synthetic version of both hormones has always been the same (scam) - i.e. they are just like the bioidentical steroids, only better...and safer. Of course, none of these claims has ever been tested/proven in human clinical trials. Now, while the dangers of estrogen (both synthetic and natural) have largely been uncovered (yet currently disputed by Big Pharma) as a result of the Women Health Initiative (WHI) studies, the dangers of synthetic progestins are largely kept under wraps. Even when a damning study about them appears in a scientific journal the industry aggressively lobbies the scientific news outlets to write the popular press articles about "progesterone" and avoid mentioning both the synthetic progestins as well as suggesting that there may be any difference between the synthetic and bioidentical version. Thus, over the years, Big Pharma has made sure that natural progesterone got all the negative press while the synthetic progestins remained largely shielded. Here is just a small list of studies that barely begins to expose the giant scam on synthetic progestins.

Natural Progesterone May Help Breast Cancer Treatment: Study
https://medicalxpress.com/news/2016-12-breast-cancer-patients-benefit-controversial.html
The estrogenic activity of synthetic progestins used in oral contraceptives enhances fatty acid synthase-dependent breast cancer cell proliferation... - PubMed - NCBI
Genomic agonism and phenotypic antagonism between estrogen and progesterone receptors in breast cancer

In addition to the breast cancer link to synthetic progestins, and the protective effects of natural progesterone, there are also studies linking the synthetic progestins to heart disease (CVD). Those studies also claim natural progesterone has a protective effect.

Different cardiovascular effects of progestins according to structure and activity. - PubMed - NCBI

I stumbled upon an older study that demonstrates potent antihypertensive effect of natural progesterone, as opposed to synthetic progestins, and states that it is lower progesterone levels in men that may account for their higher risk of CVD, as well as for the equalized CVD risk in women after menopause. Hence, the study makes the call for using only natural progesterone and not the synthetic progestins if proper cardiovascular health is desired.

Natural progesterone and antihypertensive action. - PubMed - NCBI

"...Blood concentrations of progesterone in premenopausal women are high in the luteal phase of each ovulatory menstrual cycle but fall to 30% of the follicular phase in postmenopausal women. Men have similarly low blood concentrations of progesterone. The results of this pilot study suggest that natural progesterone produces a significant reduction in blood pressure at doses which give plasma concentrations that are just above luteal phase concentrations. The physiology of progesterone suggests that its antihypertensive action is peripheral, although an additional central action cannot be excluded. In this study the less predictable reduction of erect blood pressure could have been due to the presumed vasodilation action of natural progesterone being overridden by reflex sympathetic vasoconstrictor activity. We suggest that progesterone is a "protective" female hormone. The low blood progesterone concentrations present after the menopause could account for the finding that the prevalence of high blood pressure and incidence of cardiovascular disease in women tend to catch up with those in men.1 This property would recommend the use of natural progesterone in combined oral contraceptives instead of synthetic gestagens."
 

Trambak

Member
Joined
Jun 19, 2016
Messages
34
@haidut This is very interesting!
How to translate this to a daily supplement dosage of CortiNon, for a man: "The results of this pilot study suggest that natural progesterone produces a significant reduction in blood pressure at doses which give plasma concentrations that are just above luteal phase concentrations." 5 drops daily would cover it? Or, like, 4 drops, 3 times a day?
I sure will try this. I already planned to use CortiNon for anti-aging et c, but wanted to finish my 3 month of Bulgarian Tribulis first (I'm six weeks in). Perhaps it's OK to stack them?
 
Similar threads
Thread starter Title Forum Replies Date
haidut Natural Progesterone Treats Breast Cancer, Synthetic Progestins Promote It Scientific Studies 14
haidut Natural (but Not Synthetic) Progesterone Stops Breast Cancer Scientific Studies 10
ShotTrue Supplements To Increase Natural Progesterone? Progesterone 16
Adnada "Natural Cycles" Birth Control App And Progesterone Use Female Issues 2
M Is This A Natural Progesterone? Progesterone 25
A Natural Progesterone IUD? Progesterone 2
M Natural sources of policosanol: Wheat, sugar cane and beeswax Diet 4
D Any Good "Natural" Shampoos Out There? Hair & Nails 2
W Armour vs Natural Desiccated thyroid Ask For Help or Advice 16
D Where Can I Get Real Whole Cistanche Natural Form >No Powders/Tinctures etc. Supplements, Pharmaceutical Drugs 7
Epistrophy Pregnenolone + Testosterone Base = All natural pain killer Experiments 24
S Increase natural phenylethylamine production? Mental Issues 2
D Any Such Thing As Natural Alternative To Afrin/Flonase >Stuffed Nose - Help Eyes, Ears, Nose and Headaches/Migraines 9
deliciousfruit potent natural antibiotic Digestion 7
S What's "Natural" anyway? - Luke Smith Meditation, Mindfullness, Religion, Spirituality 0
Lenny Are "Crown Prince Natural, Whole Oysters, Packed In Water" Any good and freeze-able? Seafood 5
Vinny It Is IMPOSSIBLE To Distinguish Artificial (false) Honey From Natural One Sugar, Honey 0
wealthofwisdom Refined Oil Vs Natural Substance Hair & Nails 0
johnwester130 Anyone In Terested In Natural Herbs? Do They Work? Things Like Schisandra Etc Supplements 25
md_a Ray Peat's Newsletter - Natural Order And Gilbert Ling - March 2020 Articles & Newsletters 0
Hans Agmatine Is A Natural Amino Acid With Amazing Health Benefits Articles & Scientific Studies 40
Gadreel Natural Thyroid Pills Or Synthyroid Supplements, Pharmaceutical Drugs 0
Lorof March 2020 - Natural Order And Gilbert Ling Articles & Newsletters 9
L March 2020 - "Natural Order And Gilbert Ling" Discussion Articles & Newsletters Discussion 4
Lewis Acid Evaluation Of Natural Products On Inhibition Of (COX-2) & Nitric Oxide Scientific Studies 0
S Effect Of Natural Aromatase Inhibitors On Libido Supplements 48
N Woman's Liver Failed From A Natural Supplement? Supplements, Pharmaceutical Drugs 14
paulwalkerrip Natural Eggshell Membrane - Source Of Calcium? Supplements 2
_lppaiva Got Cascara Sagrada In It's Most "natural" Form. Now What Do I Do? Cascara Sagrada 0
Locutus Crystal Geyser Sparkling Natural Mineral Water, 12oz Glass Bottles, 24 Pack Diet 0
Inaut How Light Governs Physiology: Nutrition, Natural Sunlight And Photobiomodulation With Bart Kay Light 1
bzmazu Google Scrubs Natural Health Sites Breaking News 26
S How Can I Increase My Natural Insulin Synthesis? Blood Sugar 4
Peatogenic Natural Antibiotic/Antiviral Regimen (autoimmune Condition Prevention) Ask For Help or Advice 9
J Does NDT Halt Natural Production Or Does It 'Add' To Natural Production? Natural Dessicated Thyroid 7
bzmazu Natural Environment Lowers Cortisol Levels Stress 0
R Increasing Natural Test Production With Pregnenolone Supplements, Pharmaceutical Drugs 2
Cirion Studies Of Effects Of Natural PUFA's Vs. Vegetable Oils? Polyunsaturated Fats, Seed Oils 27
Momado965 Natural Serotonin Antagonists Supplements, Pharmaceutical Drugs 2
A Antibiotic Drugs Vs Natural Antibiotics Ask For Help or Advice 12
L Pregnenolone, Dependence, Natural Production, Taper Off Pregnenolone 4
Lokzo What Are Some Natural IRON Chelators? Supplements, Pharmaceutical Drugs 23
T Would Dessicated Thyroid Supplementation Hamper Natural T3 Production? Natural Dessicated Thyroid 8
SOMO NATURAL Anti-Histamine Besides Quercetin? TCM Possibly? Supplements 28
T Willow Bark Extract (natural Aspirin) Makes My Stomach Feel Squeezy And Queezy Ask For Help or Advice 4
M Aspirin - A Natural Perspective Aspirin 4
ddjd Orange Peel - Natural Antihistamine Ask For Help or Advice 26
Repas du soir Should Natural Aromatase-inhibitors That Reduce 5α-Reductase Be Avoided? Diet 2
DaveFoster Sedentary Steroid Users Grow Double The Rate Of Natural Bodybuilders Hormones 54
Westside PUFAs Hershey's Busts Out The Natural Chocolate Syrup Sweets, Snacks 67

Similar threads

Top