progesterone

  1. K

    Progesterone Best Practices?

    I've got a bottle of Progest-E in my cart, and before I click buy, I want to clear up some uncertainties I have about progesterone. For some reason I'm a little nervous to use it? 24/F | 5ft.3" | 120 lbs | Eating pretty peaty, while maintaining food freedom / having grace with myself if I eat a...
  2. Jon444

    Spellbreaker’s Ascending Muscle Solitarium - A Peatybuilding Video Log

    Welcome to Spellbreaker’s Ascending Muscle Solitarium (name under construction) In short, this will be a video log on my progress doing bodybuilding while incorporating Ray Peat’s views… mixed with my own. The current goal is to become healthier, more androgenic, feel better and gain muscle...
  3. jpgio

    How much topical progesterone (progest-e) to start with for a man?

    Want to start using progesterone topically just curious to see how much a man should start with. Thank you.
  4. Soren

    Pregnenolone vs Progesterone for Back Pain, Endotoxin, Parkinsons Disease

    As some on this forum might know my mother suffers from Parkinson's disease which I have been attempting to treat with a number of serotonin blocking substances. Circumstances of the Pandemic and her own disposition have made it very difficult to get her into consistently good habits and...
  5. P

    Progesterone feminizing effects?

    I want to start trying progesterone to address some high cortisol/estrogen symptoms I am experiencing (sleep interruptions, digestive issues, low energy/brain fog etc.) but I have read that it may not be a good supplement for men. I have even seen some forum users say it started to physically...
  6. Lejeboca

    Ray Peat Interview July 19, 2021 - One Radio Network

    Don't see it posted yet. Enjoy! Dr. Ray Peat, Ph.D - The Dance with Progesterone & Estrogen; Our Health and Well Being Explained - July 19, 2021 | One Radio Network Detailed information on progesterone for both men and women, dosages of vitamin E and D. Answers to lots of good questions.
  7. U

    Is TSH supposed to be higher or lower during pregnancy?

    I have heard according to Peat that tsh should be less than 1. Tsh was 2.3 at 13 weeks pregnant and was 1.8 while not pregnant.
  8. S

    Pregnenolone vs Progesterone for under developed cognitive function

    I am 23, male. My cognitive function (verbal IQ) is underdeveloped due to my mom being vegan and undereating during pregnancy. I also under eat whilst growing up, was mainly vegetarian. Therefore, I was was wondering if taking for short term either pregnenolone or progesterone would help restore...
  9. Hans

    One of the best TRT alternatives (natural potent stack)

    Going on TRT can be a challenging decision. How long are you going to be on? How are you going to get off? Do you want to get off? What about fertility, risks, success rate, etc? I'm not trying to say TRT shouldn't be an option, but want to give an alternative. Fixing hypogonadism naturally is...
  10. Mauritio

    Long term DHEA supplementation doubles androgens and progesterone in males

    I'm not sure if this study has been posted before , at least I haven found anything under the "DHEA" tag. Anyways, it's always good to have more in vivo evidence for peaty substances and what they do in real life. This study gave aging men with partial androgen deficiency (58-69)the "low dose"...
  11. haidut

    AlloP - Liquid Allopregnanolone For Lab/R&D

    Just a quick announcement that we have replaced the 5α-DHP in our store with allopregnanolone. The main reason for switching over to allopregnanolone is that we always wanted to provide that steroid right from the start, however we could not find a lab willing to synthesize it. Thus, 5α-DHP...
  12. P

    Progesterone Suppresses GAD enzyme MRNA (If progesterone excites you, it may be glutamate)

    Progesterone increases glutamate in the brain via blocking GAD enzyme Progesterone increases glutamate in the brain via blocking GAD enzyme activity, this can lead to overexcitation and depression via glutamate excess. From the start the use of Progesterone felt bad to me and I knew it was...
  13. haidut

    Stress causes/exacerbates allergies, pregnenolone/progesterone therapeutic

    Yet another studies demonstrating the "controversial" link between stress and a condition doctors insist has nothing to do with stress or hormones in general. This time the culprit is CRF/CRH, which is the initial step in the "stress" cascade and is now known to be implicated in conditions such...
  14. haidut

    Endocrine disruptors in cosmetics may cause postpartum depression, premature births

    Hardly a surprising finding, but it will probably come as a shock to most modern women who are the biggest consumers of such products (e.g. nail polish, perfumes, shampoo, etc). One of the reasons for this "controversy" is that doctors continue to insist that using such products during pregnancy...
  15. N

    Progesterone soaking my panties help!

    So started taking progesterone finally . Ordered from ona Naturals and rub 3-4 drops on gums in the am so about 15-20mg. Only been doing this for about 3 days and this is a TMI WARMING but I am so so horny all the time , in fact I have been thinking about sex throughout the day much more often...
  16. Hans

    How to protect yourself against exercise-induced endotoxin absorption

    Endotoxin can significantly negatively affect your health, from chronic low-grade inflammation, joint degeneration, organ inflammation and dysfunction, brain degeneration, insulin resistance, etc. Most people know that gut dysbiosis can increase endotoxin production and absorption into the body...
  17. U

    Maca during early pregnancy?

    I have heard claims that maca boosts progesterone levels and also estrogen (enough progesterone can balance it out) boosts fertility and lowers the rate of pregnancy loss. If a woman is 10 weeks pregnant would this be a thing to try or avoid?
  18. G

    Topicals on Arteries to Maximize Follicle Exposure

    These questions are partially related to my ongoing experiment of applying DHEA and Progesterone to my scalp for hair regrowth. I have an idea about the location of topicals, and I wanted to get some thoughts on it because I am not the most knowledgeable person when it comes to human anatomy...
  19. U

    Progesterone use in pregnancy causes homosexuality?

    I am starting to doubt progesterone supplementing in pregnancy since I know someone who took natural progesterone and it made her spot during early pregnancy. This study claims that adults whose mothers took progesterone in pregnancy are more likely to be gay or bisexual. I was under the...
  20. jzone56

    Progesterone first observations

    27 yr male 185 lbs ~15% bf time of day: 8pm post-workout Method of administration: topical Location: inner wrist Dosage: ~1.7mg Gabaergic effects felt 30-50mins post administration. other observations: 1. testicles retreated closer to the body, sack became tight 2. some sort of tightness...
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