frustrated
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- Aug 30, 2012
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Re: Forums, Websites, Blogs Where They Are Discussing Ray Pe
Enig's response to Peat was poor and obnoxious.
EFA advocates: PUFAs are essential because when animal or humans were deprived they died or had skin issues.
Ray Peat: That's because lack of PUFA increases metabolism and the need for nutrients. In another experiment giving the PUFA-free rats B6 solved the problem.
EFA advocates: Vitamin B6 is promotes synthesis of AA and DHA from LA and LNA, thus it attenuates an EFAD. This an MIT study from 40's that elucidates the issue.
http://www.gwu.edu/~nsarchiv/radiation/ ... br4e1c.txt
RP: Although the 1929 Burr paper is still often cited as proof of the essentiality of PUFA, Burr's younger colleague (at the University of Minnesota Hormel Institute), Ralph Holman, has cited an infant (1970), and a 78 year old woman (in 1969), who developed dermatitis while receiving fat-free intravenous feedings.
EFA advocates: There were also studies with healthy young men showing the emergence of efad on tpn http://www.ncbi.nlm.nih.gov/pmc/articles/PMC436563/
RP: Dermatitis, with dandruff, similar to Burr's disease, has been produced by various nutritional deficiencies besides vitamin B6, including a trace mineral deficiency and a biotin deficiency, so there is no valid reason to associate dermatitis with a fat deficiency.
EFA advocates: This is only a half-truth. With true TPN deficiencies, like zinc, there are a lot more problems that start to develop (http://www.ncbi.nlm.nih.gov/pubmed/413809).
EFA advocates: PUFAs are required to form the cell membrame.
Ray Peat: Human cells can grow and divide in artificial culture solutions which contain none of the polyunsaturated fats, and no one has claimed that they are growing “without membranes.”
EFA advocates: Where is his source for this claim? Cells cultured with no efa fill up with mead acid and die [url=http://www.pnas.org/cgi/content/abstract/92/4/1147]http://www.pnas.org/cgi/content/abstract/92/4/1147
Enig's response to Peat was poor and obnoxious.
EFA advocates: PUFAs are essential because when animal or humans were deprived they died or had skin issues.
Ray Peat: That's because lack of PUFA increases metabolism and the need for nutrients. In another experiment giving the PUFA-free rats B6 solved the problem.
EFA advocates: Vitamin B6 is promotes synthesis of AA and DHA from LA and LNA, thus it attenuates an EFAD. This an MIT study from 40's that elucidates the issue.
http://www.gwu.edu/~nsarchiv/radiation/ ... br4e1c.txt
The dermatitis which developed after two
to four weeks on a fat-free pyridoxine-free diet was partially cured
by feeding pyridoxine, and completely cured when both pyridoxine and
linoleic acid were added. The percentage of arachidonic acid in the
carcass fatty acids was lowest when olive oil and pyridoxine were
present in the diet of the rats. The total amount of arachidonic acid
was greatest in those rats fed pyridoxine in the diet. It is obvious
that pyridoxine and arachidonic acid are interrelated in metabolism.
RP: Although the 1929 Burr paper is still often cited as proof of the essentiality of PUFA, Burr's younger colleague (at the University of Minnesota Hormel Institute), Ralph Holman, has cited an infant (1970), and a 78 year old woman (in 1969), who developed dermatitis while receiving fat-free intravenous feedings.
EFA advocates: There were also studies with healthy young men showing the emergence of efad on tpn http://www.ncbi.nlm.nih.gov/pmc/articles/PMC436563/
RP: Dermatitis, with dandruff, similar to Burr's disease, has been produced by various nutritional deficiencies besides vitamin B6, including a trace mineral deficiency and a biotin deficiency, so there is no valid reason to associate dermatitis with a fat deficiency.
EFA advocates: This is only a half-truth. With true TPN deficiencies, like zinc, there are a lot more problems that start to develop (http://www.ncbi.nlm.nih.gov/pubmed/413809).
EFA advocates: PUFAs are required to form the cell membrame.
Ray Peat: Human cells can grow and divide in artificial culture solutions which contain none of the polyunsaturated fats, and no one has claimed that they are growing “without membranes.”
EFA advocates: Where is his source for this claim? Cells cultured with no efa fill up with mead acid and die [url=http://www.pnas.org/cgi/content/abstract/92/4/1147]http://www.pnas.org/cgi/content/abstract/92/4/1147