Not really. I found Elixa Probiotic | Ultra High Strength Probiotic to be much better and felt immediate relief and its histamine friendly.Did you find the megasporebiotic to be helpful against candida/overgrowth or gut health in general?
I have read about people getting a histamine reaction on it. I also might think its the spores action against pathogens and in their die-off their is a sort of a herx reactionI only took it few days cause I got my typical histamine symptoms from it pretty bad