"When candida ends up in your bloodstream it's over!"

Sam321

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I wanted to ask about this for a long time but I always forget.
So Georgi said in a podcast with Danny that if candida ends up in your bloodstream "it's over". I wondered what specifically that means. It seems so discouraging and set in stone.

Does that mean that you are screwed for the rest of your life and cannot get rid of it no matter what you do?
I ask this because I do seem to have some systemic things (balanitis-like condition on my penis for a couple of years) and in my early age I always had problem with candida.

So I would really appreciate @haidut to explain in a very short terms what he meant.
I was pretty shook by that took. I think he is mostly talking about extremely immunosuppressed people like HIV/AID folks or what have you.
He totally could have worded that a bit more nicely though to not scare the ***t out of us lol.
 

Sam321

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"When candida ends up in your bloodstream it's over!" is just bull****. If Ray said this I suspect he meant that it can be game over. Candida in the blood can be serious and fatal in severely immuno-compromised persons, but can be amenable to treatment, and it usually doesn't affect normally healthy people. Notice below that mortality is high in people suffering from candida, ie, those who are immuno-compromised. Healthy people don't suffer from it.




I think many people confuse candida in the blood for "D-arabinitol" in the blood, which is the by product some candida can ***t out after eating your carbs or whatever. It sucks and can cause insomnia and anxiety and ***t, but also its far from the the "its over" point.
 

Perry Staltic

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I was pretty shook by that took. I think he is mostly talking about extremely immunosuppressed people like HIV/AID folks or what have you.
He totally could have worded that a bit more nicely though to not scare the ***t out of us lol.

I think we can all trend towards hyperbole at times to get a point across, but when taken at face value it doesn't convey the same meaning.
 

Sam321

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Thanks. It's interesting that Ray talks about fungus entering the bloodstream while dismissing candida?

I think Georgi talked specifically about candida in the bloodstream.

Ray also said "It can linger in your lungs". That one if so intriguing since for years I have these random chest pains.

The pain sometimes feel like a broken ribcage.
SIBO can cause acid reflux and burp up acid to the entery point of your lungs inflaming them. That could be your chest pain if you have stomach issues. I believe that is what is going on with me and I thought for sure I had a massive candida overgrowth.
 

haidut

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I wanted to ask about this for a long time but I always forget.
So Georgi said in a podcast with Danny that if candida ends up in your bloodstream "it's over". I wondered what specifically that means. It seems so discouraging and set in stone.

Does that mean that you are screwed for the rest of your life and cannot get rid of it no matter what you do?
I ask this because I do seem to have some systemic things (balanitis-like condition on my penis for a couple of years) and in my early age I always had problem with candida.

So I would really appreciate @haidut to explain in a very short terms what he meant.

Quite a few sources for those claims. Here are some. Apparently, nitric oxide (NO) is one of the things that plays a key role in turning the Candida infection from gut-localized into systemic/lethal. The mortality figures listed below are actually with the strongest anti-fungal treatments in a hospital ICU. With no anti-fungal treatment, the mortality is much higher.
"...Invasive candidiasis is an infection (candidiasis) that can be caused by various species of Candida yeast. Unlike Candida infections of the mouth and throat (oral candidiasis) or vagina (Candidal vulvovaginitis), invasive candidiasis is a serious, progressive, and potentially fatal infection that can affect the blood (fungemia), heart, brain, eyes, bones, and other parts of the body.[1][2]"

"...Mortality rate (percentage of people who die) in critically ill people who develop systemic candidiasis is estimated to be between 45-50%.[1] Estimates of the mortality rate for candidemia (Candida infection in the blood) range from 19-30%.[2] "


"...Fungal infections, such as those from C. albicans, are a common form of bloodstream infections in hospitals, particularly in very sick or immunocompromised patients. They can also lead to sepsis-like disease. Fungi cause untold harm, largely because they are so similar to mammalian cells that very few antifungal therapies are available. There is no sure-fire way to treat or prevent C. albicans infections."

"...Although C. albicans lives in the gut of about half of all people, it has an ability to transform into a form in which it can invade tissues and also escape from immune cells. In the gut, C. albicans sits in a benign state until the right opportunity occurs, when it can overgrow and also start to form hyphae or filaments. These filaments are elongated, stick-shaped cells that the yeast can use to push through the gut wall and get access to the bloodstream and organs, so that it can spread its infection. Associate Professor Ana Traven, from the Monash Biomedicine Discovery Institute, and her team have shed new light on how C. albicans shape-shifts to the deadly hyphal version. "

"..."We revealed a mechanism that operates in C. albicans cells to promote hyphal switching via a molecule called nitric oxide -- opening a new avenue for understanding this key process and potentially leading to development of new antifungal drugs in the future," Associate Professor Traven said."


@Perry Staltic @Sam321
 
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UG Krishnamurti
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SIBO can cause acid reflux and burp up acid to the entery point of your lungs inflaming them. That could be your chest pain if you have stomach issues. I believe that is what is going on with me and I thought for sure I had a massive candida overgrowth.
Nope. Not in my case for sure. My pain always happens when I eat something which is metabolically on the higher scale. Mixing fried fats and sugars (Eating honey and butter for example) etc.
 

Perry Staltic

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if they aren’t quickly destroyed by white blood cells — they can grow and quickly kill the person. In a typical year, a few people in the world get invasive candida and quickly die..."

Can usually doesn't happen because the if usually does happen, and the few people per year quickly killed are immuno-compromised, usually due to chemotherarpy, or critically ill stuff like sepsis.
 
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UG Krishnamurti
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Quite a few sources for those claims. Here are some. Apparently, nitric oxide (NO) is one of the things that plays a key role in turning the Candida infection from gut-localized into systemic/lethal. The mortality figures listed below are actually with the strongest anti-fungal treatments in a hospital ICU. With no anti-fungal treatment, the mortality is much higher.
"...Invasive candidiasis is an infection (candidiasis) that can be caused by various species of Candida yeast. Unlike Candida infections of the mouth and throat (oral candidiasis) or vagina (Candidal vulvovaginitis), invasive candidiasis is a serious, progressive, and potentially fatal infection that can affect the blood (fungemia), heart, brain, eyes, bones, and other parts of the body.[1][2]"

"...Mortality rate (percentage of people who die) in critically ill people who develop systemic candidiasis is estimated to be between 45-50%.[1] Estimates of the mortality rate for candidemia (Candida infection in the blood) range from 19-30%.[2] "


"...Fungal infections, such as those from C. albicans, are a common form of bloodstream infections in hospitals, particularly in very sick or immunocompromised patients. They can also lead to sepsis-like disease. Fungi cause untold harm, largely because they are so similar to mammalian cells that very few antifungal therapies are available. There is no sure-fire way to treat or prevent C. albicans infections."

"...Although C. albicans lives in the gut of about half of all people, it has an ability to transform into a form in which it can invade tissues and also escape from immune cells. In the gut, C. albicans sits in a benign state until the right opportunity occurs, when it can overgrow and also start to form hyphae or filaments. These filaments are elongated, stick-shaped cells that the yeast can use to push through the gut wall and get access to the bloodstream and organs, so that it can spread its infection. Associate Professor Ana Traven, from the Monash Biomedicine Discovery Institute, and her team have shed new light on how C. albicans shape-shifts to the deadly hyphal version. "

"..."We revealed a mechanism that operates in C. albicans cells to promote hyphal switching via a molecule called nitric oxide -- opening a new avenue for understanding this key process and potentially leading to development of new antifungal drugs in the future," Associate Professor Traven said."


@Perry Staltic @Sam321
Thank you so much @haidut !
Well, that does seem discouraging to be honest xd

Would a simple blood test for candida be enough to know for sure if candida is present in the bloodstream? Would you ever get false positives?

If you were to give advice to a rat that has systemic candidemia what would you suggest? Did we ever witnessed full recovery from patients in these stages?
 
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Perry Staltic

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Quite a few sources for those claims. Here are some. Apparently, nitric oxide (NO) is one of the things that plays a key role in turning the Candida infection from gut-localized into systemic/lethal. The mortality figures listed below are actually with the strongest anti-fungal treatments in a hospital ICU. With no anti-fungal treatment, the mortality is much higher.
"...Invasive candidiasis is an infection (candidiasis) that can be caused by various species of Candida yeast. Unlike Candida infections of the mouth and throat (oral candidiasis) or vagina (Candidal vulvovaginitis), invasive candidiasis is a serious, progressive, and potentially fatal infection that can affect the blood (fungemia), heart, brain, eyes, bones, and other parts of the body.[1][2]"

"...Mortality rate (percentage of people who die) in critically ill people who develop systemic candidiasis is estimated to be between 45-50%.[1] Estimates of the mortality rate for candidemia (Candida infection in the blood) range from 19-30%.[2] "


"...Fungal infections, such as those from C. albicans, are a common form of bloodstream infections in hospitals, particularly in very sick or immunocompromised patients. They can also lead to sepsis-like disease. Fungi cause untold harm, largely because they are so similar to mammalian cells that very few antifungal therapies are available. There is no sure-fire way to treat or prevent C. albicans infections."

"...Although C. albicans lives in the gut of about half of all people, it has an ability to transform into a form in which it can invade tissues and also escape from immune cells. In the gut, C. albicans sits in a benign state until the right opportunity occurs, when it can overgrow and also start to form hyphae or filaments. These filaments are elongated, stick-shaped cells that the yeast can use to push through the gut wall and get access to the bloodstream and organs, so that it can spread its infection. Associate Professor Ana Traven, from the Monash Biomedicine Discovery Institute, and her team have shed new light on how C. albicans shape-shifts to the deadly hyphal version. "

"..."We revealed a mechanism that operates in C. albicans cells to promote hyphal switching via a molecule called nitric oxide -- opening a new avenue for understanding this key process and potentially leading to development of new antifungal drugs in the future," Associate Professor Traven said."


@Perry Staltic @Sam321

A bit of pathogen porn in that sciencedaily.com article, very similar to a lot of covid porn we're seeing now. It mentions the pathology without qualifying it with the requisite context, ie, right opportunity = severely compromised immune system.

Although C. albicans lives in the gut of about half of all people, it has an ability to transform into a form in which it can invade tissues and also escape from immune cells. In the gut, C. albicans sits in a benign state until the right opportunity occurs, when it can overgrow and also start to form hyphae or filaments

However, the article author does indirectly mention the context briefly.

As the population living with weakened immune systems (including HIV and transplant patients, those undergoing chemotherapy and preterm babies) increases, the threat of this fungus is growing.
 
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Sam321

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Quite a few sources for those claims. Here are some. Apparently, nitric oxide (NO) is one of the things that plays a key role in turning the Candida infection from gut-localized into systemic/lethal. The mortality figures listed below are actually with the strongest anti-fungal treatments in a hospital ICU. With no anti-fungal treatment, the mortality is much higher.
"...Invasive candidiasis is an infection (candidiasis) that can be caused by various species of Candida yeast. Unlike Candida infections of the mouth and throat (oral candidiasis) or vagina (Candidal vulvovaginitis), invasive candidiasis is a serious, progressive, and potentially fatal infection that can affect the blood (fungemia), heart, brain, eyes, bones, and other parts of the body.[1][2]"

"...Mortality rate (percentage of people who die) in critically ill people who develop systemic candidiasis is estimated to be between 45-50%.[1] Estimates of the mortality rate for candidemia (Candida infection in the blood) range from 19-30%.[2] "


"...Fungal infections, such as those from C. albicans, are a common form of bloodstream infections in hospitals, particularly in very sick or immunocompromised patients. They can also lead to sepsis-like disease. Fungi cause untold harm, largely because they are so similar to mammalian cells that very few antifungal therapies are available. There is no sure-fire way to treat or prevent C. albicans infections."

"...Although C. albicans lives in the gut of about half of all people, it has an ability to transform into a form in which it can invade tissues and also escape from immune cells. In the gut, C. albicans sits in a benign state until the right opportunity occurs, when it can overgrow and also start to form hyphae or filaments. These filaments are elongated, stick-shaped cells that the yeast can use to push through the gut wall and get access to the bloodstream and organs, so that it can spread its infection. Associate Professor Ana Traven, from the Monash Biomedicine Discovery Institute, and her team have shed new light on how C. albicans shape-shifts to the deadly hyphal version. "

"..."We revealed a mechanism that operates in C. albicans cells to promote hyphal switching via a molecule called nitric oxide -- opening a new avenue for understanding this key process and potentially leading to development of new antifungal drugs in the future," Associate Professor Traven said."


@Perry Staltic @Sam321
In your opinion, does having candida albicans present in your stool in small amounts suggest that it is an over growth or causing an issue? Also, if both SIBO and candida is present, is there a pecking order for dealing with this scenario or do you try to hit them both at the same time?
 

Lonewolfx

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Maybe ten years ago, a friend of a friend of mine, who lived in a black mold infested apartment got very seriously ill and was told by his doctor that he won’t have much longer to live.

My friend suggested to him to take chlorine dioxide, which he did and he recovered after a couple of months. He had tears in eyes when he told my friend that his doctor gave him a clean bill of health!

So I think that also in the case of candida in the blood stream, the chlorine dioxide should kill the candida and the person suffering from it should be able to recover.
Any idea of the sourcing and dosing of the chlorine dioxide? I lived in a black mold infested home for a couple decades when I was younger.
 
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Travis was a fan of boron for Candida, and he subscribed to the theory that joint issues could be caused by the candida yeast living in them. When a person takes boron and their joint issues get worse initially, it may mean that the candida is dying off( the boron is binding to their chitin structure I believe). If this happens in the gut, the feeling can be similar to taking an antibiotic( in bacterial die off, there can be a surge of endotoxins, for fungal die off, I think it's beta- glucans which are released).

Niacinamide is also good for fungal issues, but the doses have to be a bit high. Boron+ niacinamide+ oregano oil could be a nice stack.
 
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Travis was a fan of boron for Candida, and he subscribed to the theory that joint issues could be caused by the candida yeast living in them. When a person takes boron and their joint issues get worse initially, it may mean that the candida is dying off( the boron is binding to their chitin structure I believe). If this happens in the gut, the feeling can be similar to taking an antibiotic( in bacterial die off, there can be a surge of endotoxins, for fungal die off, I think it's beta- glucans which are released).

Niacinamide is also good for fungal issues, but the doses have to be a bit high. Boron+ niacinamide+ oregano oil could be a nice stack.
Tried it. Didn't work for me.
 

StephanF

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Any idea of the sourcing and dosing of the chlorine dioxide? I lived in a black mold infested home for a couple decades when I was younger.
You could consult this website:


The ‘Protocol 1000’ calls for three activated drops (three drops of NaClO2 plus three drops of 4%-5% HCl) every hour for 8 hours. But best to start slowly with one activated drop.
 
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Vitamin D3 a new drug against Candida albicans​

 

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