^ Looks useful for people who get fatty stools / problems with low bile. Taurine conjugates fat soluable bile acids produced by the liver & gives them an added water soluble property which helps in the process of fat absorption through some mechanism
Conjugated bile acids are the major components of human bile, with their total concentration exceeding that of any other metabolite in bile. Taurine-conjugated bile acids can also inhibit biofilm formation of bacteria.
also Is taurine good for the gut? 10 reasons why it may... - Hack your gut
Effects of taurine on gut microbiota and metabolism in mice - PubMed may help with h.pylori
When H. Pylori breaks down urea, it releases ammonia and carbon dioxide. This ammonia neutralizes stomach acid and provides an environment where H. Pylori can colonize. It also has the unfortunate side effect of causing major bloating in the stomach and damage to the lining.
The release of ammonia also has another effect: it causes ulcers. When H. Pylori colonizes the stomach, it attracts neutrophils. Neutrophils are immune cells sent to contain the colonization. They enter the stomach and secrete hypochlorous acid to kill invaders. When hypochlorous acid reacts with ammonia, it creates monochloramine. Monochloramine irritates the stomach and impairs ulcer healing.
Taurine scavenges monochloramine by binding to it. This prevents the damage caused by monochloramine and speeds up the healing of ulcers(20). Unfortunately, it also means that a person with an active H. Pylori problem likely needs more taurine. When taurine binds to monochloramine, it isn’t absorbed. This means it isn’t used to conjugate bile acids or for any of the other systems that rely on it
https://journals.sagepub.com/doi/abs/10.3181/00379727-100-24741 -< 3x 500mg Taurine daily markedly increased the proportion of taurine conjugated bile acids
The only problem is the GABA receptor downregulation from day to day use so potential to cause anxiety over time. so i'm wondering
1. how much taurine it takes to cause that and
2. if taking smaller doses through the day for smaller spikes in activation would lessen this downregulation effect or if it would be worse more frequently?
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