absorption

Hey all, I take my vitamin E softgels orally because they're too hard to squeeze when cut open, but I take them with meals and I drink coffee a lot with my meals. Does coffee interfere with oral vitamin E absorption? Thank you

One of the most common questions I get from my readers is "What is the topical absorption rate of your products?" There are a number of studies demonstrating that a solvent mixture of DMSO/ethanol achieves close to 100% absorption no matter where on the skin it is applied. However, we stopped...

As many forum users know, magnesium (Mg) is one of the most important minerals for proper metabolic function. It is a required cofactor for hundreds of metabolic enzymes, including the crucial mitochondrial enzyme pyruvate dehydrogenase (PDH), ATP synthesis, and ATP transport in the bloodstream...

High dietary fat is one of the primary factors for increased endotoxin load, especially if the fat is PUFA. This is probably one of the main reasons Peat prefers lower fat diets. However, most of the studies on the fat-endotoxin link so far have been on animal models. This new human study...

This claims has been made many times, and is even listed on the Wikipedia page. However, I have not been able to find the actual reference to back this up even though I have been looking for a long time. Now, thanks to @Wagner83 and his link to the "Cornell Vet" book, I found that study and I am...

The other day I checked the label on the salt which we use at the restaurant I work in and discovered it contained sodium aluminosilicate, an anti-caking agent.I scoured the web searching for other unexpected routes of exposure and must now conclude that virtually every processed food available...

As discussed in another thread related to DHEA, subcutaneous administration of steroids is considered the golden standard for bioavailability and systemic effects. That same study showed that topical application of DHEA dissolved in popylene glycol is only 33% as bioavailable as through...

Ray Peat takes his vitamin E with olive oil. He rubs it on his wrists probably. He also applies vitamin D3 mixed in olive oil transdermally. This probably aids in the absorption of those fat-soluble vitamins. But maybe there is more to it. Most vitamin E supplements are derived from soya oil...

There have been a couple of posts recently along the lines that "the Peat diet" was low in zinc and that high calcium intake would deplete zinc. So I decided to check what information I could find about it. My conclusion: A diet that contains adequate animal proteins from milk, eggs, and...

and lowers homocysteine and therefore atherosclerosis Sounds like it might be worth taking if eating out along with your vitamin E and tryptophan transport blockers Taurine and Homocysteine Reduction Taurine can protect against coronary artery disease by favorably modulating blood levels of...

Just a note for those using the two nutrients together. http://www.ncbi.nlm.nih.gov/pubmed/3720797 "...The effects of caffeine on the pharmacokinetics and bioavailability of aspirin were studied in 12 healthy adult male volunteers. The subjects received 650 mg of aspirin or 650 mg of aspirin...

Calcium and Iron Interactions Inhibition of haem-iron absorption in man by calcium http://journals.cambridge.org/action/di ... 4593000546 Calcium: effect of different amounts on nonheme- and heme-iron absorption in humans. http://ajcn.nutrition.org/content/53/1/112.short...

For those asking about my steroid supplements, and why use DMSO as a carrier (questions mostly coming from the Facebook RP groups). The studies below show that transdermal application of steroids (including progesterone, estrogen, and testosterone) dissolved in DMSO achieved the same...

Peat has written about the benefits of tryptophan restriction for overall health and metabolism. Unfortunately, there are few reliable methods of reducing tryptophan absorption and most people have to resort to simply limiting consumption of foods high in tryptophan. It would be nice if there...

I think it was BigPapaChakra who found this: http://ajcn.nutrition.org/content/37/3/416.long The relevant part to coffee-timing is study 3:

Given how similar taurine is structurally to glycine, this is not surprising but I wanted to post it anyways as an extra option for people who do not have access to glycine powder/tablets but have taurine. http://www.ncbi.nlm.nih.gov/pubmed/7277191 "...Aspirin absorption from the stomach or...

Glycine is known to protect the gastric mucosa against any potential irritation by aspirin and other known irritants like alcohol and phosphoric acid. According to this study, glycine increases aspirin absorption 3-fold and as such people having issues with high doses aspirin can reduce their...

Influence of seven beverages on salicylate disposition in humans

I wonder how do coffee and cacao reduce iron absorption, is it selectively just targeting iron or is it reducing absorption of all minerals like zinc or selenium?

Ray hinted in some of his email correspondence that BCAA competes with tryptophan for uptake not only in the brain but in cells throughout the body. I have been searching for studies confirming that and it seems I found some. They are attached to this email. Long story short - for every unit...