You've gone beyond "Nuance" here, and you are just full on trolling at this point. If Saturated Fat can repair and restore the function of seriously damaged livers of alcoholics, why wouldn't it be beneficial for "common people" as well? Especially since NAFLD is fairly "common" in and of itself.
Besides that, there are now several animal studies, and at least two human studies (one of those studies lasting several years), posted to this thread refuting the title of this thread, and answering your initial question. I guess you can keep on shifting the goal post to "yes, okay, but what about Eskimos living in Peru that only consume 4 glasses of gin each week, where are the studies on them?" if you really want to.
Nothing is black and white, again... don't be absolutist. PUFA can have interest also in some cases, just like SFA. They are not fundamentally good or bad.
If SFA can help alcoholic why not, but if it put you at risk for diabetes, endotoxins etc... there is a benefit/risk ratio in EVERYTHING !
NAFLD and NASH are sometimes linked to... ORANGE haha. Does that mean that we should definitively avoid oranges ? Absolutely not, I even have eaten an orange this morning.
Raw orange intake is associated with higher prevalence of non-alcoholic fatty liver disease in an adult population - PubMed
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Abstract
Objectives: Non-alcoholic fatty liver disease (NAFLD) is one of the most common public health issues worldwide. Oranges are the most popular fruit consumed in the world. Admittedly, flavonoids in oranges act as antioxidants and improve liver steatosis. However, oranges also are rich in fructose, which is a risk factor in the progress of NAFLD. Therefore, we hypothesize that orange intake may be a double-edged sword in the development of NAFLD."
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Methods: We randomly recruited 27,214 adults into the Tianjin Chronic Low-Grade Systemic Inflammation and Health Cohort Study. NAFLD was diagnosed by liver ultrasonography. Raw orange intake was assessed by a validated self-administered food frequency questionnaire. Multiple logistic regression analysis was used to evaluate the association between orange intake and the prevalence of NAFLD.
Results: There was a 27.18% prevalence of NAFLD among the participants. Consumption of orange was positively associated with the prevalence of NAFLD after adjustment for all potential confounding factors (Ptrend = 0.04). The odds ratios (95% confidence interval) of the categories of orange intake in the NAFLD were 1.00 (reference) for less than once per week, 1.02 (0.95-1.11) for 1 to 6 times per week, and 1.17 (1.03-1.33) for ≥7 times per week, respectively.
Conclusions: The present study demonstrated that orange intake is positively associated with the prevalence of NAFLD."
Anyway, can we talk about nuts reducing MDA and oxidized LDL in intervention studies on humans or not ??!