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Some evidence that saturated fat can help keep you lean.
Good Fats versus Bad Fats: A Comparison of Fatty Acids in the Promotion of Insulin Resistance, Inflammation, and Obesity
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC442768/pdf/jcinvest00103-0090.pdf
"The subjects were put on three different metabolic isocaloric diets: a SFA diet, a w-6 PUFA diet, and a fish oil-enriched diet called the w-3 PUFA diet. Each diet was fed for 25 d."
"Fasting insulin and the incremental two-hour post-prandial insulin over the fasting insulin from lowest (best) to highest (worst) were as follows, SFA diet (8 uU/ml and 10 uU/ml), omega-3 diet (12uU/ml and 14 uU/ml), and omega-6 PUFA diet (14 uU/ml and 25 uU/ml). Although the differences were not statistically significant, the particularly high insulin levels promoted by dietary omega-6 PUFAs suggests that these fatty acids in particular may promote greater fat storage compared to long-chain omega-3s or SFAs when consumed on top of a diet moderately high in carbohydrate.
Mechanisms whereby omega-6 PUFAs may promote fat mass accumulation include inhibition of omega-3s anti-obesogenic effects (such as increased fatty acid oxidation, increased basal metabolic rate, increased protein and muscle synthesis) and promotion of fat-storing prostaglandins, endocannabinoids and increased hunger."
"A randomized parallel controlled-feeding trial was performed in 60 non-diabetics (40–65 years old) with mild abdominal obesity.7 After consuming a two-week run-in diet high in saturated fat (19% energy), patients were placed on a high MUFA diet (20% energy), a Mediterranean diet (MUFA 21% energy) or high SFA diet for 8 weeks (carbohydrate intake was 47.3% energy in SFA, 46.4% in MUFA and 41.1% in Mediterranean diet). The high MUFA diet reduced TC, LDL-C and the TC/HDL compared to the SFA-diet. There was no significant difference in insulin levels or insulin sensitivity between the diets (no difference in C-peptide, HOMA-IR and glucose). The authors concluded, “…in our controlled-feeding trial, a high MUFA-diet and a Mediterranean diet did not affect insulin sensitivity compared to a high SFA-diet.”"
"This result was similar to a paper published by Lovejoy and colleagues comparing diets high in SFA (9%), MUFA (9%) or trans-fat (9%) that found no difference in insulin sensitivity on top of a high carbohydrate intake (57% energy).8 However, insulin sensitivity did worsen by 24% in the SFA versus the MUFA diet in overweight subjects."
So overweight people might benefit more from lower fat diets and maybe a bit higher MUFA. Luckily animal fat is also high in MUFA.
Good Fats versus Bad Fats: A Comparison of Fatty Acids in the Promotion of Insulin Resistance, Inflammation, and Obesity
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC442768/pdf/jcinvest00103-0090.pdf
"The subjects were put on three different metabolic isocaloric diets: a SFA diet, a w-6 PUFA diet, and a fish oil-enriched diet called the w-3 PUFA diet. Each diet was fed for 25 d."
"Fasting insulin and the incremental two-hour post-prandial insulin over the fasting insulin from lowest (best) to highest (worst) were as follows, SFA diet (8 uU/ml and 10 uU/ml), omega-3 diet (12uU/ml and 14 uU/ml), and omega-6 PUFA diet (14 uU/ml and 25 uU/ml). Although the differences were not statistically significant, the particularly high insulin levels promoted by dietary omega-6 PUFAs suggests that these fatty acids in particular may promote greater fat storage compared to long-chain omega-3s or SFAs when consumed on top of a diet moderately high in carbohydrate.
Mechanisms whereby omega-6 PUFAs may promote fat mass accumulation include inhibition of omega-3s anti-obesogenic effects (such as increased fatty acid oxidation, increased basal metabolic rate, increased protein and muscle synthesis) and promotion of fat-storing prostaglandins, endocannabinoids and increased hunger."
"A randomized parallel controlled-feeding trial was performed in 60 non-diabetics (40–65 years old) with mild abdominal obesity.7 After consuming a two-week run-in diet high in saturated fat (19% energy), patients were placed on a high MUFA diet (20% energy), a Mediterranean diet (MUFA 21% energy) or high SFA diet for 8 weeks (carbohydrate intake was 47.3% energy in SFA, 46.4% in MUFA and 41.1% in Mediterranean diet). The high MUFA diet reduced TC, LDL-C and the TC/HDL compared to the SFA-diet. There was no significant difference in insulin levels or insulin sensitivity between the diets (no difference in C-peptide, HOMA-IR and glucose). The authors concluded, “…in our controlled-feeding trial, a high MUFA-diet and a Mediterranean diet did not affect insulin sensitivity compared to a high SFA-diet.”"
"This result was similar to a paper published by Lovejoy and colleagues comparing diets high in SFA (9%), MUFA (9%) or trans-fat (9%) that found no difference in insulin sensitivity on top of a high carbohydrate intake (57% energy).8 However, insulin sensitivity did worsen by 24% in the SFA versus the MUFA diet in overweight subjects."
So overweight people might benefit more from lower fat diets and maybe a bit higher MUFA. Luckily animal fat is also high in MUFA.
