Dietary Nitrate Inhibits Iodide Uptake

[Kasper]

Perchlorate competitively blocks iodide from entering the thyroid. Those thyroid-related effects of environmental perchlorate have created great health concerns. However, nitrate, found in spinach, beets and other vegetables, seem to have similar or worse effects than perchlorate, as this study shows. This may also a reason to not eat carrots in too high quantities, as carrots also contain nitrates.

Perchlorate versus other environmental sodium/iodide symporter inhibitors: potential thyroid-related health effects.
Perchlorate is a known competitive inhibitor of the sodium/iodide symporter (NIS). Possible thyroid-related effects of environmental perchlorate have created great health concerns, especially in the US, resulting in a debated reference dose (RfD) of 0.0007 mg/kg per day in drinking water recommended by the National Academy of Sciences (NAS). However, the impact of other environmental NIS inhibitors and the role of iodine seem to have received little attention in the whole debate.

The relative potencies of prevalent environmental NIS inhibitors (nitrate, thiocyanate and perchlorate) to inhibit iodine uptake have been estimated repeatedly with robust results. Our calculations show that nitrate and thiocyanate, acquired through drinking water or food, account for a much larger proportion of iodine uptake inhibition than perchlorate. Furthermore, the iodine uptake inhibitory effects of nitrate and thiocyanate - as defined by their legally accepted maximal contaminant levels in drinking water - exceed the potential effect of the proposed RfD for perchlorate by far.

 

[Sunrise]

May thjre be some food or environmental elemenet tjat reduce nitrates ? For example uv light exposure or other? For spinachs, does only consuming its broth and not the leef may reduce nitrate content?

 

[Mauritio]

Wow this another peace of the puzzle and a good reason to take iodine.

Just an example from germany:
The waste that is a result from cleaning in the purification plant is used as fertilizer on the fields , there is too much waste that's why they must put more and more on the fields lol , i think 3x as much as its allowed, that's the same for decades.
Germany even has to pay fees to the EU , but rather pay those fees than really do something for the environment . This mud is very high in nitrates and think about where it goes when they use it in the fields : in the ground, food and water . That's a fukking scandal but nobody gives a damn ,these lobby workers do their business.
And simultaneously every german thinks they have the best rap water in the world , I mean that's where the nitrates go...

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