I hope your appointment goes well! Testing can be very informative, it's good you're doing that. I've been meaning to suggest two tests to you, these are very pervasive inflammatory mediator: one is Tumor Necrosis Factor and the other one is Interleukin-6. These tests are highly recommended by a MD (who happens to be a biologist as well, Dr. Theoharides) specializing in crazy illnesses like ours, chronic allergic kinda stuff, hypersensitivity... I'm sharing these with you because doctors usually test for things like C-Reactive protein to check for inflammation, but this test is not always reliable, it very often comes back very nice and you can have a tremendously bad inflammatory degenerative process. They also order histamine, and often comes back nice. So, one ends up not knowing what's going on. You can read more about this issues here Confused by a negative histamine test result?Interesting thought PakPik. My first thought is that it's not the fillers that are a problem though, because I have reacted to many foods and herbs too...not just supplements, just some things from my kitchen that offer good health benefits. I'm not ruling out this idea, of course. Obviously there's some mystery here to solve. It could have to do with my liver, and poor detoxification. Tomorrow I have a MD appointment and I'm going to go for it...liver, pancreas, etc. testing. I'll keep you posted! Thanks Hon!