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Serotonin Inhibits The Senses

Discussion in 'Scientific Studies' started by haidut, Aug 23, 2014.

  1. haidut

    haidut Member

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    The hallucinogenic effects of LSD are thought to be due to removing of the inhibition of the "thinking" part of the brain over sensory responsivity. This implies that serotonin inhibits that responsivity. This study seems to confirm that view and makes one wonder how something that inhibits the senses like SSRI can be good for depression.

    http://www.plosone.org/article/info%3Ad ... ne.0105941

    "...The inhibition of sensory responsivity is considered a core serotonin function, yet this hypothesis lacks direct support due to methodological obstacles. We adapted an optogenetic approach to induce acute, robust and specific firing of dorsal raphe serotonergic neurons. In vitro, the responsiveness of individual dorsal raphe serotonergic neurons to trains of light pulses varied with frequency and intensity as well as between cells, and the photostimulation protocol was therefore adjusted to maximize their overall output rate. In vivo, the photoactivation of dorsal raphe serotonergic neurons gave rise to a prominent light-evoked field response that displayed some sensitivity to a 5-HT1A agonist, consistent with autoreceptor inhibition of raphe neurons. In behaving mice, the photostimulation of dorsal raphe serotonergic neurons produced a rapid and reversible decrease in the animals' responses to plantar stimulation, providing a new level of evidence that serotonin gates sensory-driven responses."
     
  2. Vinero

    Vinero Member

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    I think that when your health is poor serotonin increases so you don't feel the full extent of how messed up your health really is. Serotonin numbs the senses so you don't have to deal with it. Imagine taking LSD when you are having severe health problems, it would likely be a confronting experience as you become awake to how toxic, fat or catabolic your body really is.
     
  3. Such_Saturation

    Such_Saturation Member

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  4. passivity

    passivity Member

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  5. Such_Saturation

    Such_Saturation Member

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    !!!!!!!!!!!!!!! really? I must inform Rich, man. He'd be ecstatic probably. The man always has something going on.
     
  6. passivity

    passivity Member

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    :ss
     
  7. Such_Saturation

    Such_Saturation Member

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    The guy writes two books at a time. All from superego liberation. Writing some paper about CBD oil currently. Lives in the woods. Very energetic person.
     
  8. passivity

    passivity Member

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    Thats so nice.

    Id love to live in the woods

    Do you think lithium would be more or less safe for bipolar disorder?
     
  9. Regina

    Regina Member

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    Neat.
     
  10. dookie

    dookie Member

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    Can you give a quick summary of his practical recommendations? That document seems massive on philosophy and smart lingo
     
  11. dookie

    dookie Member

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    Just look around at reviews of lithium on the internet. It doesn't seem safe at all.
    Why not just do high dose sodium? At least the risks are much smaller
     
  12. dookie

    dookie Member

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    @haidut

    Does estrogen always equal high serotonin? What would be worse for increasing serotonin, estrogen or cortisol?
     
  13. passivity

    passivity Member

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    I eat a lot of salty food. French fries on butter and chicharrones.

    Maybe a low dose of lithium would be ok?

    Lithium Experiences
     
  14. dookie

    dookie Member

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    @passivity

    I had a horrible experience from a few mg's of lithium carbonate, along with diarrhea and insomnia. Try other things first I would say.
     
  15. passivity

    passivity Member

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    ok thank you.
     
  16. Ideonaut

    Ideonaut Member

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    ? superego liberation is the key to his energeticness? I'd like to learn more.
     
  17. dookie

    dookie Member

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  18. Such_Saturation

    Such_Saturation Member

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    I think he associated certain ideas of Freud with the Default Mode Network, as some neuroscientist has already written about. I quote some paragraphs that contain one practical exercise, but there are plenty of pdf books of his that he can send you if you want more.

     
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