General Orange
Member
I dont care if that dr Sam is the king of my country.no he's a doc take him literaly for his word he is not being abstract or cryptic in any way
cortisol is anti inflammatory not anti stress...it is THE STRESS HORMONE
dopamine would get rid of serotonin faster...than cortsiol...DO SOME COCAINE BOOM serotonin gone.
mic drop and out the door....peace
Cortisol is released as anti stress mechanism with feedback loop:
Relationships between inflammatory cytokine and cortisol responses in firefighters exposed to simulated wildfire suppression work and sleep restriction
A fundamental relationship exists between the immune and endocrine systems to modulate an adequate response to physiological and psychological stressors (Mcewen et al. 1997; Turnbull and Rivier 1999; Elenkov and Chrousos 2002; Elenkov 2008). The precise physiological mechanisms underlying this relationship are not fully understood. Evidence does suggest that activation of a bidirectional feedback loop between the end-products, cytokines and cortisol, is central to the appropriate functioning of the hypothalamic–pituitary–adrenal (HPA) axis, while maintaining homeostasis of the immune system (Turnbull and Rivier 1999; Petrovsky 2001). For example, exposure to a stressor and the subsequent release of certain inflammatory cytokines such as tumor necrosis factor-alpha (TNF-α), interleukin (IL)-10, and IL-6 activate the HPA axis and cause the release of cortisol (Turnbull and Rivier 1999; Steensberg et al. 2003). The anti-inflammatory effects of cortisol then feedback and suppress further release of cytokines (Riechlin 1993; Chrousos 1995; Elenkov and Chrousos 1999; Turnbull and Rivier 1999).