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Anecdotal Evidence MSM Regrows Hair - Nitric Oxide Antagonist!

Discussion in 'Ask For Help or Advice' started by Joeyd, Jun 12, 2018.

  1. Joeyd

    Joeyd Member

    Joined:
    Jul 13, 2014
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    MSM has been shown to decrease the production of nitric oxide (NO) and mitochondrial ROS, decreasing initial levels of oxidative stress.

    I have long suspected that the root cause of hair loss is high nitric oxide (and estrogen, cortisol), and low CO2.

    I believe Red Light, Methylene Blue and Emodin, which all dissociate Nitric Oxide from Cytochrome C Oxidase are the most effective tools in the fight against hair loss.

    I now suspect that MSM may also possess similar properties due to scientific literature proving that it reduces Nitric Oxide, and the astoundingly large anecdotal evidence that it halts hair loss and stimulates new hair growth.

    STUDIES:

    The anti-inflammatory effects of methylsulfonylmethane on lipopolysaccharide-induced inflammatory responses in murine macrophages. - PubMed - NCBI
    "MSM significantly inhibited the release of nitric oxide and prostaglandin E(2) by alleviating the expression of inducible nitric oxide synthase and cyclooxygenase-2 in LPS-stimulated RAW264.7 cells."

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372953/
    "MSM can also diminish the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) through suppression of NF-κB; thus lessening the production of vasodilating agents such as nitric oxide (NO) and prostanoids [86]. NO not only modulates vascular tone [92] but also regulates mast cell activation [93]; therefore, MSM may indirectly have an inhibitory role on mast cell mediation of inflammation. "
     
  2. benaoao

    benaoao Member

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    Apr 21, 2018
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    You’re suspecting - no anecdotal evidence related to hair growth.

    Let me rephrase this

    Close enough- the root cause of hair loss is whatever is leading to high NO, e2, Cortisol (and prolactin, DHT, adrenaline...) and low CO2. Those are responses and adaptations to a cellular problem. They trigger more dysfunctions, fine, but they wouldn’t be too high (or low for co2) in the first place if the body was healthy. They all have a perfectly physiological function and nuking them is obviously dumb as seen with most drugs

    So fix:
    1) insulin resistance
    2) lifestyle biological nonsense
     
  3. BrianF

    BrianF Member

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    And how would one increase levels of MSM in the body?
     
  4. OP
    Joeyd

    Joeyd Member

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    Take it as a supplement. It's dirt cheap
     
  5. OP
    Joeyd

    Joeyd Member

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    What would you suggest for fixing insulin resistance?
     
  6. BrianF

    BrianF Member

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    Thanks. To be honest, ive always suffered various ailmemts that might be attributed to high NO. Cold sores (herpes simplex) for example.
     
  7. benaoao

    benaoao Member

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    The same dietary fixes that I’ve mentioned to you yesterday.

    And no they don’t come in a pill :)
     
  8. Ras

    Ras Member

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    Sep 12, 2015
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    Right. One must find the root of the disorder.
     
  9. Motif

    Motif Member

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    What thread?

    @benaoao

    And you wrote you get your collagen in Europe. Which one? And will this have the same effect as gelatin?
     
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