Chamomille Reduces Nitric Oxide

jyb

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Nov 9, 2012
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Not sure if its as significant as carrot or cascara in reducing nitric oxide, but I just came across this study. I also need to get my hands on the full study to know more about their Chamomille source and treatment.


http://www.ncbi.nlm.nih.gov/pubmed/21042790

Chamomile: an anti-inflammatory agent inhibits inducible nitric oxide synthase expression by blocking RelA/p65 activity.


Chamomile has long been used in traditional medicine for the treatment of inflammation-related disorders. In this study we investigated the inhibitory effects of chamomile on nitric oxide (NO) production and inducible nitric oxide synthase (iNOS) expression, and explored its potential anti-inflammatory mechanisms using RAW 264.7 macrophages. Chamomile treatment inhibited LPS-induced NO production and significantly blocked IL-1β, IL-6 and TNFα-induced NO levels in RAW 264.7 macrophages. Chamomile caused reduction in LPS-induced iNOS mRNA and protein expression. In RAW 264.7 macrophages, LPS-induced DNA binding activity of RelA/p65 was significantly inhibited by chamomile, an effect that was mediated through the inhibition of IKKβ, the upstream kinase regulating NF-κB/Rel activity, and degradation of inhibitory factor-κB. These results demonstrate that chamomile inhibits NO production and iNOS gene expression by inhibiting RelA/p65 activation and supports the utilization of chamomile as an effective anti-inflammatory agent.
 

SOMO

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Mar 27, 2018
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Love chamomile tea.
 

jamies33

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Nov 14, 2017
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chamomile + honey + salt + gelatin -> most "dreamy" sleep tonic :cat::cat:
 

D Man

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Mar 5, 2018
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That’s a great idea - I usually drink it alone and it knocks me for 6

Honey and salt will put me away for days
 
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