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nitric oxide

  1. Mauritio

    1 dose of endotoxin causes endothelial dysfunction for up to 1 week

    In this study they injected endotoxin into the hand of healthy volunteers. As it turned out, one dose of endotoxin lead to persistent constriction of the blood vessel that took up to 1 week to recover! There's molecules like nitric oxide, serotonin , bradikinin ,arachidonic acid or CO2 that...
    • Mauritio
    • Thread
    • blood vessels endothelial dysfunction endotoxin nitric oxide no
    • Replies: 8
    • Forum: Scientific Studies
  2. D

    Is it safe to take agmatine with herpes?

    I have been found to have an active herpes virus and I have neurological symptoms and ADHD. But I also have migraines sometimes, and I would like to take agmatine to reduce nitric oxide. Is it safe?
    • Daniil
    • Thread
    • adhd agmatine herpes nitric oxide
    • Replies: 1
    • Forum: Additives
  3. Mauritio

    Cistanche increases steroidogenic enzymes, lowers NO, helps osteoporosis and Alzheimer's

    I posted these studies in another thread, but I feel they deserve their own thread as they show that cistanche is helping the body on a systemic level. A few new studies on cistanche tubulosa: This one shows that cistanche increases biosynthesis of testosterone by increasing important...
    • Mauritio
    • Thread
    • alzheimer's cistanche cistanche tubulosa enzymes nitric oxide no osteoporosis steroids testosterone
    • Replies: 186
    • Forum: Scientific Studies
  4. NodeCerebri

    Methylene Blue lowering nitric oxide too much?

    I want to add methylene blue to my daily stack, currently at about 300 mcg. It is bearable right now, but I think the nitric oxide lowering effects are increasing my blood pressure. -I want to up the dose, but scared of too high BP then. -I also want to up the dose, but everything above 400 mcg...
    • NodeCerebri
    • Thread
    • blood pressure methylene blue nitric oxide serotonin
    • Replies: 1
    • Forum: Supplements
  5. K

    Lack of optimism, enthusiasm, excitement and also ED

    Hi, despite being a fit and active 39-year-old, I've had a few issues that have plagued much of my adult life, namely: -erectile dysfunction (I've tested my NO levels, using strips and they are constantly low, despite taking L-arginine/Citrulline, which I've come to realise is unlikely to help...
    • K2000
    • Thread
    • comt epigenetics genetics mthfr nitric oxide nos3
    • Replies: 8
    • Forum: Mental Issues
  6. Mauritio

    Serotonin Causes Obesity, Diabetes, Fibrosis,liver Damage ,increases Endotoxin And NO

    Inspired by this thread Serotonin/endotoxin/PUFA As Primary Causes Of Depression And Diabetes; Can Be Easily Blocked I was reading a few more recent studies on the detrimental effect of serotonin on ones health. It seems clear that by now it is known in medicine, that blocking it is highly...
    • Mauritio
    • Thread
    • diabetes endotoxin fibrosis nitric oxide no obesity serotonin tlr4 tph tph inhibitor
    • Replies: 4
    • Forum: Scientific Studies
  7. haidut

    Drop In Androgen Levels Causes Parkinson Disease (PD), DHT Reverses It

    Yet another study demonstrating that many of the so-called chronic, degenerative and above all "mysterious" conditions often have quite a simple cause and, potentially, treatment. There is no need for mutated genes or complex interactions of genes with environment that nobody can decipher...
    • haidut
    • Thread
    • 5α-dihydrotestosterone androgen brain castration cns dht dopamine gdnf inos neurodegeneration neurodegenerative neuroinflammation nitric oxide no parkinson parkinson's disease testosterone α-synuclein
    • Replies: 39
    • Forum: Scientific Studies
  8. haidut

    Arginine / Glutamine Depletion May Treat Cancer By Blocking The Warburg "Effect"

    As my readers have noticed, I started putting quotes around the "effect" part of the infamous observation made by Otto Warburg himself. Over the last 3-4 years, even mainstream medicine has started to publish studies acknowledging that the "effect" is very much a cause as well. In other words...
    • haidut
    • Thread
    • arginine cancer cure depletion fatty acid oxidation glutamine nitric oxide treat tumor warburg effect
    • Replies: 13
    • Forum: Scientific Studies
  9. haidut

    Nitrates In Tap Water May Cause 12,500+ Cancer Cases Annually

    Despite the billions of dollars poured into advertising by municipal water authorities trying to convince people, the evidence for the negative effects of drinking such water just keeps piling on. Fluoride has been added for decades, despite the constant stream of research demonstrating its ill...
    • haidut
    • Thread
    • cancer cause epa nitrate nitrates nitric oxide no tap water
    • Replies: 6
    • Forum: Scientific Studies
  10. haidut

    Osteoporosis Is Caused By Mitochondrial Dysfunction Driven By Nitric Oxide (NO)

    Let’s repeat the mantra one more time – structure and function cannot be separated, they are mutually dependent at every level of reality/life. As such, it is little surprise (to us) that a structural disorder like osteoporosis may be caused by a deficiency in energy production. Yet, despite...
    • haidut
    • Thread
    • bone breakdown cause cytochrome c cytochrome c oxidase damage dysfunction energetic inflammation metabolic mitochondria nitric oxide no osteoclasts osteoporosis rankl resorption stress
    • Replies: 10
    • Forum: Scientific Studies
  11. haidut

    Low-dose Aspirin Blocks Multiple Sclerosis (MS) And Reverses Its Damage

    A few years ago I posted a study showing that 1.2g aspirin daily greatly ameliorated fatigue in MS patients and was considered safe enough even at that high dose to be recommended for daily use. Sunlight And Aspirin Can Treat Multiple Sclerosis (MS) However, those studies did not look at...
    • haidut
    • Thread
    • aspirin baby aspirin blocks cures inflammation inos low-dose ms multiple sclerosis myelin nitric oxide no stops treats
    • Replies: 45
    • Forum: Scientific Studies
  12. P

    “NO” To Autophagy: Fat Does The Trick For Diabetes

    “NO” to Autophagy: Fat Does the Trick for Diabetes During the progression from obesity to diabetes, a critical attribute is inability to maintain metabolic homeostasis under excessive energy and nutrient exposure, which triggers insulin resistance. Intensive research efforts have linked chronic...
    • paymanz
    • Thread
    • autophagy diabetes hyperinsulinemia inflammation insulin insulin sensitivity mitophagy nitric oxide obesity tlr4
    • Replies: 0
    • Forum: Articles & Scientific Studies
  13. P

    Interstitial Sodium

    I highlighted some parts but other parts are interesting too https://www.sciencedirect.com/science/article/pii/S0735109714071782 Consequently, a large amount of Na+ is bound to GAGs, creating a microenvironment of hypertonic Na+concentration (19). However, the dense network exhibits a low...
    • paymanz
    • Thread
    • extracellular matrix glycoproteins glycosaminoglycans interstitial fluid lymphatic nitric oxide salt sodium vasopressin
    • Replies: 4
    • Forum: Articles & Scientific Studies
  14. haidut

    Breaking News: Viagra Given To Pregnant Women Is Lethal For The Babies

    As horrifying as it sounds, prescribing NO-boosting drugs to pregnant women is apparently perfectly acceptable in the search of more profit. The doctors probably got misled by the common practice in NICU of giving babies with pulmonary hypertension (or other breathing problems) an inhalation...
    • haidut
    • Thread
    • babies fetus lethal lung damage lung disease nitric oxide no pah poison pregnancy pregnant pulmonary arterial hypertension pulmonary fibrosis sildenafil toxic unborn viagra
    • Replies: 4
    • Forum: Scientific Studies
  15. haidut

    Dietary Nitrates Can Cause Mania After Just Two Weeks Of Consumption

    As many forum users already know dietary nitrates are an effective precursor to nitric oxide (NO). NO has been reliably linked to mania in humans, and mania is a known side effect of drugslike Viagra or nitroglycerin, but so far the official claim is that dietary nitrate intake does not cause...
    • haidut
    • Thread
    • diet humans mania mental health mental illness microbiome nitrate nitrates nitric oxide no
    • Replies: 41
    • Forum: Scientific Studies
  16. ddjd

    Nitric Oxide Isoforms - Information Needed!

    If you have any conflicting or supporting studies or information perhaps you could contribute! Aspirin (lowers ALL - eNOS, iNOS, nNOS conflicting - possibly raises eNOS) Arginine (raises eNOS, nNOS, iNOS) Agmatine (raises eNOS lowers nNOS, iNOS) Caffeine (lowers eNOS iNOS? nNOS?) Iodine...
  17. ddjd

    Taurine Increases Nitric Oxide

    Not very Peaty after all... Here's some studies: "taurine caused elevated concentration of 3-NT and NOx" Effects of taurine on nitric oxide and 3-nitrotyrosine levels in spleen during endotoxemia. - PubMed - NCBI "The results showed that taurine increasedserum levels of nitric oxide and...
  18. haidut

    Schizophrenia Treatment Could Be As Simple As Reducing Ammonia

    I posted a number of studies on Ceylon cinnamon and its metabolite sodium benzoate, showing their benefit in Parkinson disease, depression and anxiety. While all of those studies were on animal models, the toxicity of ammonia in the brain is undisputed and its role in all of these disease has...
    • haidut
    • Thread
    • ammonia ceylon cinnamon nitric oxide psychosis schizophrenia serine sodium benzoate treatment-resistant
    • Replies: 37
    • Forum: Scientific Studies
  19. haidut

    Methylene Blue Is A Potent Anti-inflammatory, With Possibly The Broadest Spectrum

    Some bold statements in this study, which combined both in vitro and in vivo models. The HED for methylene blue (MB) was just 0.15mg/kg, which is in the range of 10mg-15mg doses that showed great effectiveness in treating mental disorders like depression and psychosis. As you can see from the...
    • haidut
    • Thread
    • anti-inflammatory endotoxin inflammation lps metabolism methylene blue mitochondria mitochondrial respiration nitric oxide
    • Replies: 17
    • Forum: Scientific Studies
  20. haidut

    Plain (unmodified) Adamantane Is A Powerful Inhibitor Of NO Synthesis

    Many people on the forum are familiar with the beneficial properties of adamantane and its derivatives. However, most of the research conducted on the beneficial effects of these chemicals has been with adamantane derivatives such as amantadine, memantine, rimantadine, bromantane, etc. When we...
    • haidut
    • Thread
    • adamantane endotoxin inhibitor inos lps nitric oxide no synthesis
    • Replies: 11
    • Forum: Scientific Studies
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