inflammation

The study actually used the now-banned NAD+ precursor known as nicotinamide mononucleotide (NMN), but, as I keep reminding people, multiple studies have demonstrated statistically equivalent rise in NAD+ levels from equal doses of any of the known NAD+ precursors such as niacin, niacinamide...

Not sure if my readers have noticed it, but Big Pharma has drastically increased their bashing of aspirin since the pandemic started. Those attacks began when a few studies published back in 2020 demonstrated that aspirin users had a much lower risk of both contracting and dying from COVID-19...

I (late 20s Male) was diagnosed with adult ADHD last year and prescribed Adderall. I have currently been taking 10mg-30mg near daily for almost a year. I am prescribed 20mg 2x/day which I usually only do 10mg 2x/day or 20mg AM-10mg PM or even just 20mg AM, depending on what I have going on. I...

Almost a decade ago I posted about a "rogue" study which had the audacity to suggest that most of so-called viral infections (including HIV) produce most of their most severe symptoms not through the virus or its direct effects, but through synergism with the bacterial endotoxin (LPS) that we...

The rates of IBD have truly skyrocketed over the last 10-15 years, significantly surpassing the general increase seen in most chronic conditions, especially in people younger than 40. Over the last couple of years, I posted about studies showing artificial colors (e.g. Red 40), silicon dioxide...

Nothing much to add here and the article title is essentially identical to my post. I am mostly posting this as a possible "remedy" for the many people who engage in endurance exercise, usually with the (misguided) goal to lose weight. As the study says, the effects of vitamin E are most...

I did not think we will ever see such a headline in a major news outlet, but here is is. And in The Guardian of all places, which is a newspaper that rarely deviates from the official medical narrative on any condition, especially obesity and diabetes. The official narrative for those conditions...

This is one of those studies where the most important finding is not directly stated, but implied. Namely, if healing the gut barrier, as the study says, may prevent/treat RA then the condition is most likely tied to the microbiome in our GI tract. More specifically, to the byproducts of the...

I am posting this study not so much because of the link between chronic low-grade inflammation and neurological conditions it demonstrates. That link is by now well-known even in mainstream medical circles. The main reason this study/article caught by eye is that the experiment mimicked the...

It looks like vitamin D may be the "vitamin" (actually, seco-steroid) analog of aspirin - i.e. there is hardly a condition where this humble "vitamin" has not demonstrated beneficial effects. The new study now adds asthma to the list of chronic, debilitating (and potentially lethal) conditions...

I mentioned in several of my latest podcast appearances that Pfizer is running clinical trials with a serotonin antagonist to reverse/treat several lethal conditions, for which medicine claims there is no cure. Those conditions include heart fibrosis / heart failure, pulmonary hypertension...

Summary of studies: Endotoxin tolerance (ET) is a reduced responsiveness to a LPS challenge following a first encounter with endotoxin. Chronically, this may lead to local or systemic immunosuppression. Despite ongoing low-grade tissue irritation, only a blunted immune response is mounted. On...

Yet another study demonstrating that the "villain of all males around the world" - the dastardly androgen dihydrotestosterone (DHT) - actually is, in all likelihood, beneficial for males, at least when it comes to their cardiovascular health. However, since CVD is one of the risk factors for...

It looks like the interest in gut-derived pathogenic substances is steadily increasing in the medical field. After claiming for decades (and still doing so) that liver disease is either genetic in origin or driven mostly by sugar (especially fructose) consumption, now studies like the one below...

Another article demonstrating that a ubiquitous chemical, widely used in both industrial and household settings, has very toxic effects on the GI tract of humans and can directly cause a number of GI and neurological diseases, as well as cancer. While the study only looked at the so-called...

Changes in Gut Microbiota Induced by Doxycycline Influence in Vascular Function and Development of Hypertension in DOCA-Salt Rats DOX decreased lactate-producing bacterial population and plasma lactate levels, improved gut barrier integrity, normalized endotoxemia, plasma noradrenaline levels...

At a first glance, mitochondrial dysfunction (a "functional" problem) has little in common with the build-up of plaque on arterial walls (a "structural" problem). However, as my readers know quite well, structure and function cannot be separated and a functional pathology is perfectly capable...

A very interesting study, which adds more evidence in favor of the recent hypothesis that glycine (just as taurine) is in fact an essential amino acid. Namely, despite our ability to synthesize glycine, as needed, from the truly essential amino acids, its absence in the diet leads to pathologies...

The disease ALS needs no introduction. It is perhaps the most dreaded disease in current/former athletes as it is currently considered incurable, invariably lethal, and is known to strike athletes in much higher rates than the general population. Medicine claims that about 10% of the ALS cases...

I don't think the topic needs much of an introduction. At this point, the only people who deny the causal link between SSRI use by pregnant or soon-to-become pregnant women and autism in their children are either pharma employees...or doctors who receive so much money from pharma companies to...