inflammation

  1. FallingApart?

    Covid Vaccine may be neurologically/cognitively breaking me. How do I fix it?

    A Bit of Backstory Info [You can skip this if you want]: Spent early years in a catholic private school, if I'm not mistaken, they tended to make joke(s) that the public school was one year behind them and if I'm not mistaken, in the 4th grade (maybe it was 3rd - idrk) I think I tested 8th...
  2. haidut

    Chronic pain due to mitochondrial dysfunction, niacinamide can treat it

    As many of my readers know, there is an epidemic of chronic pain disorders in Western countries, which has subsequently led to over-prescription and (ab)use of opioid medication, which has then acted as a gateway drug and fueled a massive and deadly opioid epidemic in those countries. In order...
  3. haidut

    Aspirin may reverse NAFLD/fibrosis by reducing fat accumulation, inflammation

    Another great win for aspirin, especially considering the prevalence of NAFLD, NASH, fibrosis/cirrhosis and even liver cancer. This post comes mere minutes after the post on a single tablet aspirin (300mg) daily putting a terminal liver cancer in remission. This study below used a low-dose...
  4. haidut

    Just one aspirin (300mg) daily stops a patient's terminal liver cancer

    While the evidence for aspirin's preventive effects on numerous cancer types is extensive and even mainstream medicine has begrudgingly acknowledged aspirin's prophylactic potential, studies on the therapeutic effects of aspirin in already established cancers are very few, and most of them are...
  5. haidut

    Optimal vitamin D intake may be at least 2,000 IU daily

    As most people supplementing with vitamins know, the daily RDA for vitamin D has been set at 400 IU (in some countries up to 800 IU) daily, despite no evidence that such doses do anything beneficial, including even the basic target - preventing rickets. More recent studies have argues that the...
  6. Mauritio

    Narirutin + Didymin

    Narirutin is the secon most common flavonoid in orange juice, but is little talked about. Here are some interesting studies: 1. Anti-depressant effect - Narirutin produces antidepressant-like effects in a chronic unpredictable mild stress mouse model - PubMed 2. Lowers inflammation via...
  7. haidut

    LipOdd - Liquid Product With Odd-Chain Saturated Fats (SFA)

    More than a decade ago, when I was just beginning my exploration of bioenergetics, one of the first indications that Ray's writings were onto something when it came to SFA vs. PUFA was the fact that while mainstream medicine ruthlessly bashed SFA in general and promoted PUFA, virtually very...
  8. cs3000

    Daily omega 3 EPA DHA sustains inflammation response (and slightly delays skin wound healing) in human study

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967211/
  9. haidut

    PARADOX: Cortisol promotes inflammation, drives Alzheimer's Disease (AD)

    It looks like serotonin (5-HT), commonly known as the "happy hormone" has a serious competitor for the title of the most grossly mischaracterized substance in medicine. That serious competitor is cortisol, in both its synthetic and bioidentical forms, commonly known as the "master of...
  10. cs3000

    Low Copper & Lung function (shortness of breath, copd)

    inflammation / infection lowers copper in lungs through TNF-a Copper Deficiency in the Lungs of TNF-α Transgenic Mice copper depletion can cause emphysema , lung damage Copper Deficiency Induced Emphysema Is Associated with Focal Adhesion Kinase Inactivation (copper is critical for proper...
  11. haidut

    Increasing serotonin (5-HT) breakdown delays/prevents aging

    The naked mole rat (NMR) is one of the most fascinating species. Despite being a humble rodent, much smaller than a regular house/city rat, the NMR has an exceptionally long life-span of 35+ years (compared to 2-3 years for the common rat) and on top of that is remarkably resistant to the...
  12. haidut

    Blocking prostaglandins restores (glucose) metabolism, reverses brain aging

    It is rare to find a study like the one below that combines so many crucial topics into a unified message. Namely, the role of energy in aging and disease, the role of oxidative glucose metabolism in aging and health, the pathological role of PUFA as a negative (glucose) metabolic regulator and...
  13. haidut

    Aversion to bitter taste may be a sign of endotoxin/LPS overload, chronic disease

    Just a few days ago I did a post about a study, which showed that endotoxin (LPS) makes body odor unpleasant and leads to both self-isolation and shunning from others. The study below adds more evidence to the LPS puzzle by showing that exposure to LPS strongly increased aversion to bitter...
  14. haidut

    Another "paradox" - elevated cortisol, from high-fat diet, increases inflammation

    Over the last year or so I posted about several studies demonstrating that even short-term usage of glucocorticoids may be a double-edged sword. Namely, while it is beyond doubt that, acutely, glucocorticoids suppress inflammation, those studies demonstrated that the glucocorticoids upregulated...
  15. haidut

    Raising DHT levels even only in the brain reverses systemic atherosclerosis

    As my readers know, I have been a fan of the strong, non-aromatizable androgen DHT for a long time. One of the first signs for me that DHT is beneficial was the uniform and relentless propaganda against that steroid by mainstream medical publications, despite the obvious (and increasing)...
  16. haidut

    Serotonin (5-HT) drives diabetes and liver disease, blocking it is therapeutic

    After more than a decade of doing research in bioenergetics, I have come to the conclusion that there is hardly a disease (both acute and chronic) where 5-HT is not involved as a causal factor. Out of all those conditions, the ones with the biggest public health impacts are probably obesity...
  17. haidut

    Inhibiting oxidative metabolism can cause inflammation, aggressive cancer

    Despite medicine's rabid defense of the "cancerous mutation" origin theory of cancer, it looks like evidence for the metabolic origins of cancer has always been around and hiding in "plain sight". The study below cites the apparently well-known causal link between accumulation of fumarate (a...
  18. haidut

    Illness (endotoxin) makes body odor unpleasant, may lead to social shunning

    The study below demonstrated something most of us have known intuitively since childhood. Namely, sick people not only look sick, but they also smell "sick". While this has already been established scientifically for people with terminal diseases (e.g. cancer, which increases body levels of...
  19. haidut

    Niacinamide may lower blood pressure in humans by raising NAD+

    The study actually used the now-banned NAD+ precursor known as nicotinamide mononucleotide (NMN), but, as I keep reminding people, multiple studies have demonstrated statistically equivalent rise in NAD+ levels from equal doses of any of the known NAD+ precursors such as niacin, niacinamide...
  20. haidut

    Aspirin reduces risk of developing diabetes

    Not sure if my readers have noticed it, but Big Pharma has drastically increased their bashing of aspirin since the pandemic started. Those attacks began when a few studies published back in 2020 demonstrated that aspirin users had a much lower risk of both contracting and dying from COVID-19...
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